Herpes Zoster and vaccination strategies in inflammatory bowel diseases: a practical guide

Guillo, Lucas, Rabaud, Christian, Choy, Ernest H. ORCID: https://orcid.org/0000-0003-4459-8609, D'Amico, Ferdinando, Danese, Silvio, Ng, Siew C. and Peyrin-Biroulet, Laurent 2022. Herpes Zoster and vaccination strategies in inflammatory bowel diseases: a practical guide. Clinical Gastroenterology and Hepatology 20 (3) , pp. 481-490. 10.1016/j.cgh.2020.10.027

Preview

PDF - Accepted Post-Print Version Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (248kB) | Preview

Abstract

Herpes zoster is a painful dermatomal cutaneous eruption resulting from reactivation of the latent varicella–zoster virus. Patients with inflammatory bowel diseases have an increased risk of shingles compared with the general population and this risk can be increased with the use of immunosuppressive therapy. Live zoster vaccine and recombinant zoster vaccine have shown efficacy for the prevention of herpes zoster. The recombinant zoster vaccine seems to offer greater efficacy and long-term protection profile compared with the life zoster vaccine. However, their use in clinical practice still is unclear and updated vaccination recommendations are lacking. This review discusses the risk for shingles in patients with inflammatory bowel diseases, available vaccines, and their efficacy and safety profiles. We also provide guidance on who, when, and how to vaccinate for herpes zoster in routine clinical practice among patients with inflammatory bowel diseases.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	Elsevier
ISSN:	1542-3565
Date of First Compliant Deposit:	29 June 2022
Date of Acceptance:	9 October 2020
Last Modified:	27 Nov 2024 05:45
URI:	https://orca.cardiff.ac.uk/id/eprint/150856

Citation Data

Cited 4 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item