British Society for Immunology & United Kingdom Primary Immunodeficiency Network (UKPIN) consensus guideline for the management of immunoglobulin replacement therapy

Grigoriadou, S., Clubbe, R., Garcez, T., Huissoon, A., Grosse-Kreul, D., Jolles, S., Henderson, K., Edmonds, J., Lowe, D. and Bethune, C. 2022. British Society for Immunology & United Kingdom Primary Immunodeficiency Network (UKPIN) consensus guideline for the management of immunoglobulin replacement therapy. Clinical and Experimental Immunology 210 (1) , pp. 1-13. 10.1093/cei/uxac070

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Abstract

Currently there is no guideline to support the use of immunoglobulin replacement therapy (IgRT) in primary and secondary immunodeficiency disorders in UK. The UK Primary Immunodeficiency Network (UK-PIN) and the British Society of Immunology (BSI) joined forces to address this need. Given the paucity of evidence a modified Delphi approach was employed covering statements for the initiation, monitoring, discontinuation of IgRT as well as home therapy programme. A group of 6 consultant immunologists and 3 nurse specialists created the statements, reviewed responses and feedback and agreed on final recommendations. This guideline includes 22 statements for initiation, 22 statements for monitoring, 11 statement for home therapy and 19 statements for discontinuation of IgRT. Further areas of research are proposed to improve future delivery of care.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	Oxford University Press
ISSN:	0009-9104
Funders:	N/A
Date of First Compliant Deposit:	11 August 2022
Date of Acceptance:	3 August 2022
Last Modified:	09 May 2023 09:32
URI:	https://orca.cardiff.ac.uk/id/eprint/151796

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