Molecular insights into high altitude adaption and acclimatisation of Aporrectodea caliginosa

Perry, Iain, Balazs Hernadi, Szabolcs, Cunha, Luis, Short, Stephen, Marchbank, Angela, Spurgeon, David, Orozco Ter Wengel, Pablo ORCID: https://orcid.org/0000-0002-7951-4148 and Kille, Peter ORCID: https://orcid.org/0000-0001-6023-5221 2022. Molecular insights into high altitude adaption and acclimatisation of Aporrectodea caliginosa. Life Science Alliance 5 (11) , e202201513. 10.26508/lsa.202201513

PDF - Published Version Available under License Creative Commons Attribution. Download (2MB)

Abstract

Here, we explore the high-altitude adaptions and acclimatisation of Aporrectodea caliginosa. Population diversity is assessed through mitochondrial barcoding, identifying closely related populations across the island of Pico (Azores). We present the first megabase N50 assembly size (1.2 Mbp) genome for A. caliginosa. High- and low-altitude populations were exposed experimentally to a range of oxygen and temperature conditions, simulating altitudinal conditions, and the transcriptomic responses explored. SNP densities are assessed to identify signatures of selective pressure and their link to differentially expressed genes. The high-altitude A. caliginosa population had lower differential expression and fewer co-expressed genes between conditions, indicating a more condition-refined epigenetic response. Genes identified as under adaptive pressure through Fst and nucleotide diversity in the high-altitude population clustered around the differentially expressed an upstream environmental response control gene, HMGB1. The high-altitude population of A. caliginosa indicated adaption and acclimatisation to high-altitude conditions and suggested resilience to extreme weather events. This mechanistic understanding could help offer a strategy in further identifying other species capable of maintaining soil fertility in extreme environments.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Advanced Research Computing @ Cardiff (ARCCA) Biosciences Medicine
Additional Information:	This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).
Publisher:	Rockefeller University Press
ISSN:	2575-1077
Funders:	NERC
Date of First Compliant Deposit:	18 August 2022
Date of Acceptance:	29 July 2022
Last Modified:	22 Jul 2024 16:14
URI:	https://orca.cardiff.ac.uk/id/eprint/151860

Citation Data

Cited 1 time in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item