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Polio returns to the USA: An epidemiological alert

Rai, Anushree, Uwishema, Olivier, Uweis, Lama, El Saleh, Rayyan, Arab, Sara, Abbass, Mortada, Wellington, Jack, Musabirema, Felix, Adanur, Irem and Patrick Onyeaka, Chinyere Vivian 2022. Polio returns to the USA: An epidemiological alert. Annals of Medicine and Surgery 82 , 104563. 10.1016/j.amsu.2022.104563

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License URL: http://creativecommons.org/licenses/by/4.0/
License Start date: 28 August 2022

Abstract

On July 21, 2022, the USA witnessed the first case of poliomyelitis after 3 decades of its eradication. Poliomyelitis is a crippling disease that results from infection with any one of the three related poliovirus types (referred to as types P1, P2, and P3), members of the enterovirus (picornavirus) family. The New York State Department of Health confirmed that a case of paralytic poliomyelitis was reported from a 20-year-old Hungarian traveller residing in Rockland County. The detected viral sequence has been found to have vaccine-derived poliovirus type 2 (VDPV2) suggesting an origin from the live attenuated oral polio vaccine (OPV). Since immunisation remains the only preventable measure, this article explores suggestions from the Centers for Disease Control and Prevention on reliable Inactivated (killed) polio vaccination in high-risk patients along with early case detection and treatment. In light of the above-mentioned findings, this research further details future recommendations like cessation of the OPV, encouragement of inactivated polio vaccine (IPV) in vaccination schedules, sensitive epidemiological surveillance system and appropriate training for healthcare providers. The affected countries have been further advised to have effective outbreak response strategy plans in place so that they can respond and stay prepared for such outbreaks in the future.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Additional Information: License information from Publisher: LICENSE 1: URL: http://creativecommons.org/licenses/by/4.0/, Start Date: 2022-08-28
Publisher: Elsevier
ISSN: 2049-0801
Date of First Compliant Deposit: 9 September 2022
Date of Acceptance: 28 August 2022
Last Modified: 10 Feb 2024 02:20
URI: https://orca.cardiff.ac.uk/id/eprint/152440

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