Hutter, Jana, Slator, Paddy J. ![]() |
Abstract
Purpose To investigate, visualize and quantify the physiology of the human placenta in several dimensions - functional, temporal over gestation, and spatial over the whole organ. Methods Bespoke MRI techniques, combining a rich diffusion protocol, anatomical data and T2* mapping together with a multi-modal pipeline including motion correction and extracted quantitative features were developed and employed on pregnant women between 22 and 38 weeks gestational age including two pregnancies diagnosed with pre-eclampsia. Results A multi-faceted assessment was demonstrated showing trends of increasing lacunarity, and decreasing T2* and diffusivity over gestation. Conclusions The obtained multi-modal acquisition and quantification shows promising opportunities for studying evolution, adaptation and compensation processes.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Computer Science & Informatics |
Publisher: | Wiley |
ISSN: | 0740-3194 |
Date of Acceptance: | 12 June 2018 |
Last Modified: | 06 Jul 2023 10:00 |
URI: | https://orca.cardiff.ac.uk/id/eprint/160733 |
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