The Action of Methylmagnesioum Iodide on 6-Bromo-2-Phenyl-4H-3,l-Benzoxazinone and its 4(3H)-Quinazolinones

Abdel-Megeed, Mohamed F., El-Hiti, Gamal A. and Teniou, Abdel-Rahman 1999. The Action of Methylmagnesioum Iodide on 6-Bromo-2-Phenyl-4H-3,l-Benzoxazinone and its 4(3H)-Quinazolinones. Delta Journal of Science 23 (1) , pp. 131-137.

Full text not available from this repository.

Abstract

6-Bromo-2-phenyl-4H-3,l-benzoxazinone (7) reacted with methylmagnesium iodide to give 2-benzoylamino-5- bromophenyldimethylcarbinol (8) in 54% purified yield. Similarly, 3-anilino-6-bromo-2-phenyl-4(3H)-quinazolinone (9) afforded the corresponding dimethylcarbinol 10 in 65% yield after crystallization on its reaction with methylmagnesium iodide. However, reaction of methylmagnesium iodide with 6-bromo-3-(4-chloro-phenylidene)-2-phenyl- 4(3H)-quinazolinone (11) gave 6-bromo-3-[l-(4-chlorophenyl) ethylamino]-4(3H)-quinazolinone (12) in 48% yield after purification.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry
Subjects:	Q Science > QD Chemistry
Publisher:	Faculty of Science, University of Tanta
ISSN:	1012-5965
Last Modified:	19 Mar 2016 22:26
URI:	https://orca.cardiff.ac.uk/id/eprint/16377

Actions (repository staff only)

Edit Item