Synthesis, crystal structure and in vitro anti-proliferative activity of 2-[(4-acetylphenyl)carbamoyl]phenyl acetate

Mohamed-Ezzat, Reham A., Kariuki, Benson M. ORCID: https://orcid.org/0000-0002-8658-3897 and Srour, Aladdin M. 2023. Synthesis, crystal structure and in vitro anti-proliferative activity of 2-[(4-acetylphenyl)carbamoyl]phenyl acetate. Acta Crystallographica Section E: Crystallographic Communications 79 (11) , pp. 999-1002. 10.1107/S2056989023008526

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Abstract

2-[(4-Acetyl­phen­yl)carbamo­yl]phenyl acetate, C17H15NO4, has been synthesized and structurally characterized. In the structure, N—H...O hydrogen-bonding inter­actions form chains of mol­ecules aligned along the [101] direction. The chains are linked by π–π and C—H...π inter­actions, forming a three dimensional network. The compound has been screened for in vitro anti-proliferative activity revealing considerable activity.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry
Publisher:	International Union of Crystallography
ISSN:	2056-9890
Date of First Compliant Deposit:	11 December 2023
Date of Acceptance:	27 September 2023
Last Modified:	12 Dec 2023 11:15
URI:	https://orca.cardiff.ac.uk/id/eprint/164676

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