Mohapatra, Debendra K., Pattanayak, Manas R., Das, Pragna P., Pradhan, Tapas R.  ORCID: https://orcid.org/0000-0003-1480-7799 and Yadav, J. S.
2011.
Ring-closing metathesis (RCM) based synthesis of the macrolactone core of amphidinolactone A.
Organic and Biomolecular Chemistry
9
(16)
, pp. 5630-5632.
10.1039/c1ob05335c
|
Official URL: https://doi.org/10.1039/C1OB05335C
Abstract
A convergent synthesis of the macrolactone core of amphidinolactone A has been achieved, in a 10 step linear sequence with 32% overall yield, through a ring-closing metathesis reaction as the macrolactonization step. The RCM precursor was obtained by the union of acid and alcohol fragments derived from (R)-epichlorohydrin and (R)-2,3-O-isopropylidene glyceraldehyde, respectively.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Chemistry |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1477-0520 |
| Date of Acceptance: | 11 May 2011 |
| Last Modified: | 16 May 2024 01:40 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/165587 |
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