Mohapatra, Debendra K., Pattanayak, Manas R., Das, Pragna P., Pradhan, Tapas R. ![]() |
Official URL: https://doi.org/10.1039/C1OB05335C
Abstract
A convergent synthesis of the macrolactone core of amphidinolactone A has been achieved, in a 10 step linear sequence with 32% overall yield, through a ring-closing metathesis reaction as the macrolactonization step. The RCM precursor was obtained by the union of acid and alcohol fragments derived from (R)-epichlorohydrin and (R)-2,3-O-isopropylidene glyceraldehyde, respectively.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Chemistry |
Publisher: | Royal Society of Chemistry |
ISSN: | 1477-0520 |
Date of Acceptance: | 11 May 2011 |
Last Modified: | 16 May 2024 01:40 |
URI: | https://orca.cardiff.ac.uk/id/eprint/165587 |
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