Models for Meibomian gland dysfunction: In vivo and in vitro

Bu, Jinghua, Guo, Yuli, Wu, Yang, Zhang, Rongrong, Zhuang, Jingbin, Zhao, Jiankai, Sun, Le, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Liu, Zuguo and Li, Wei 2024. Models for Meibomian gland dysfunction: In vivo and in vitro. The Ocular Surface 32 , pp. 154-165. 10.1016/j.jtos.2024.03.003

Full text not available from this repository.

Abstract

Meibomian gland dysfunction (MGD) is a chronic abnormality of the Meibomian glands (MGs) that is recognized as the leading cause of evaporative dry eye worldwide. Despite its prevalence, however, the pathophysiology of MGD remains elusive, and effective disease management continues to be a challenge. In the past 50 years, different models have been developed to illustrate the pathophysiological nature of MGD and the underlying disease mechanisms. An understanding of these models is crucial if researchers are to select an appropriate model to address specific questions related to MGD and to develop new treatments. Here, we summarize the various models of MGD, discuss their applications and limitations, and provide perspectives for future studies in the field.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Optometry and Vision Sciences
Additional Information:	License information from Publisher: LICENSE 1: Title: This article is under embargo with an end date yet to be finalised.
Publisher:	Elsevier
ISSN:	1542-0124
Date of Acceptance:	12 March 2024
Last Modified:	18 Mar 2024 10:45
URI:	https://orca.cardiff.ac.uk/id/eprint/167309

Actions (repository staff only)

Edit Item