Browse by Current Cardiff authors

Lewis, Philip N., Young, Robert D., Souza, R. B., Quantock, Andrew J. and Meek, Keith M. 2021. Contrast-enhanced tissue processing of fibrillin-rich elastic fibres for 3D visualization by volume scanning electron microscopy. Methods and Protocols 4 (3) , 56. 10.3390/mps4030056

Ashworth, Sean, Harrington, Jodie, Hammond, Greg M., Bains, Kiranjit K., Koudouna, Elena, Hayes, Anthony J., Ralphs, James R., Regini, Justyn W., Young, Robert D., Hayashi, Ryuhei, Nishida, Kohji, Hughes, Clare E. and Quantock, Andrew J. 2021. Chondroitin sulfate as a potential modulator of the stem cell niche in cornea. Frontiers in Cell and Developmental Biology 8 , 567358. 10.3389/fcell.2020.567358

Young, Robert D., Knupp, Carlo, Koudouna, Elena, Ralphs, James R., Ma, Yanhui, Lwigale, Peter Y., Jester, James V. and Quantock, Andrew J. 2020. Observations on nascent matrix structures in embryonic cornea: Important in cell interactions, or merely vestiges of the lens surface? Archives of Clinical and Experimental Ophthalmology 2 (2) , pp. 67-72. 10.46439/ophthalmology.2.014

Hammond, Greg M., Young, Robert D., Muir, Duncan D. and Quantock, Andrew J. 2020. The microanatomy of Bowman’s layer in the cornea of the pig: changes in collagen fibril architecture at the corneoscleral limbus. European Journal of Anatomy 24 (5) , pp. 399-406.

Wang, Kehao, Hoshino, Masato, Uesugi, Kentaro, Yagi, Naoto, Young, Robert D., Frost, Bethany E., Regini, Justyn W., Quantock, Andrew J. and Pierscionek, Barbara K. 2020. Cell compaction is not required for the development of gradient refractive index profiles in the embryonic chick lens. Experimental Eye Research 197 , 108112. 10.1016/j.exer.2020.108112

Kobayashi, Yuki, Hayashi, Ryuhei, Shibata, Shun, Quantock, Andrew J. and Nishida, Kohji 2020. Ocular surface ectoderm instigated by WNT inhibition and BMP4. Stem Cell Research 46 , 101868. 10.1016/j.scr.2020.101868

Meek, Keith M., Quantock, Andrew J., Hayes, Sally and Bell, James 2020. X-ray diffraction imaging of corneal ultrastructure. In: Ahearne, Mark ed. Corneal Regeneration: Methods and Protocols, Vol. 2145. Methods in Molecular Biology, New York, NY, USA: Humana, pp. 231-247. (10.1007/978-1-0716-0599-8_16)

Baba, Koichi, Sasaki, Kei, Morita, Mio, Tanaka, Tomoyo, Teranishi, Yosuke, Ogasawara, Takahiro, Oie, Yoshinori, Kusumi, Izumi, Inoie, Masukazu, Hata, Ken-ichiro, Quantock, Andrew J., Kino-oka, Masahiro and Nishida, Kohji 2020. Cell jamming, stratification and p63 expression in cultivated human corneal epithelial cell sheets. Scientific Reports 10 (1) , 9282. 10.1038/s41598-020-64394-6

Morgan, Sian R., Pilia, Nicole, Hewitt, Melissa, Moses, Rachael L., Moseley, Ryan, Lewis, Philip N., Morrison, Peter W. J., Kelly, Steven L., Parker, Josie E., Whitaker, David, Quantock, Andrew J. and Heard, Charles M. 2020. Controlled in vitro delivery of voriconazole and diclofenac to the cornea using contact lenses for the treatment of Acanthamoeba keratitis. International Journal of Pharmaceutics 579 , 119102. 10.1016/j.ijpharm.2020.119102

Hewitt, Melissa G., Morrison, Peter W. J., Boostrom, Hannah M., Morgan, Siân R., Fallon, Melissa, Lewis, Philip N., Whitaker, David, Brancale, Andrea, Varricchio, Carmine, Quantock, Andrew J., Burton, Matthew J. and Heard, Charles M. 2020. In Vitro Topical Delivery of Chlorhexidine to the Cornea: Enhancement Using Drug-Loaded Contact Lenses and β-Cyclodextrin Complexation, and the Importance of Simulating Tear Irrigation. Molecular Pharmaceutics 17 (4) , pp. 1428-1441. 10.1021/acs.molpharmaceut.0c00140

Matsushita, Kenji, Kawashima, Rumi, Uesugi, Koji, Okada, Haruka, Sakaguchi, Hirokazu, Quantock, Andrew J. and Nishida, Kohji 2020. Assessment of a self-assembling peptide gel, SPG-178, in providing a clear operative field for trabeculectomy surgery for glaucoma in an animal model. Scientific Reports 10 (1) , 11326. 10.1038/s41598-020-68171-3

Young, Robert D., Knupp, Carlo, Koudouna, Elena, Ralphs, James R., Ma, Yanhui, Lwigale, Peter Y., Jester, James V. and Quantock, Andrew J. 2019. Cell-independent matrix configuration in early corneal development. Experimental Eye Research 187 , 107772. 10.1016/j.exer.2019.107772

Bains, Kiranjit Kaur, Fukuoka, Hideki, Hammond, Greg M., Sotozono, Chie and Quantock, Andrew J. 2019. Recovering vision in corneal epithelial stem cell deficient eyes. Contact Lens and Anterior Eye 42 (4) , pp. 350-358. 10.1016/j.clae.2019.04.006

Hayashi, Ryuhei, Ishikawa, Yuki, Katayama, Tomohiko, Quantock, Andrew J. and Nishida, Kohji 2018. CD200 facilitates the isolation of corneal epithelial cells derived from human pluripotent stem cells. Scientific Reports 8 (1) , 16550. 10.1038/s41598-018-34845-2

Shibata, Shun, Hayashi, Ryuhei, Okubo, Toru, Kudo, Yuji, Katayama, Tomohiko, Ishikawa, Yuki, Toga, Junko, Yagi, Emiko, Honma, Yoichi, Quantock, Andrew J., Sekiguchi, Kiyotoshi and Nishida, Kohji 2018. Selective laminin-directed differentiation of human induced pluripotent stem cells into distinct ocular lineages. Cell Reports 25 (6) , pp. 1668-1679. 10.1016/j.celrep.2018.10.032

Koudouna, Elena, Mikula, Eric, Brown, Donald J., Young, Robert D., Quantock, Andrew J. and Jester, James V. 2018. Cell regulation of collagen fibril macrostructure during corneal morphogenesis. Acta Biomaterialia 79 , pp. 96-112. 10.1016/j.actbio.2018.08.017

Morgan, Sian, Hieda, O., Nakai, Y., Boote, Craig, Hayes, Sally, Kinoshita, S., Meek, Keith and Quantock, Andrew 2018. Microwave treatment of the cornea leads to localised disruption of the extracellular matrix. Scientific Reports 8 , 13742. 10.1038/s41598-018-32110-0

Littlechild, Stacy, Young, Robert D., Caterson, Bruce, Yoshida, H., Yamazaki, M., Sakimura, K., Quantock, Andrew J. and Akama, T.O. 2018. Keratan sulfate phenotype in the β-1,3-N-acetylglucosaminyltransferase-7-null mouse cornea. Investigative Ophthalmology and Visual Science 59 , pp. 1641-1651. 10.1167/iovs.17-22716

Kobayashi, Y., Hayashi, R., Quantock, Andrew J. and Nishida, K. 2017. Generation of a TALEN-mediated, p63 knock-in in human induced pluripotent stem cells. Stem Cell Research 25 , pp. 256-265. 10.1016/j.scr.2017.10.015

Soma, T., Koh, S., Maeda, N., Mitomo, K., Quantock, Andrew J. and Nishida, K. 2017. A new graft insertion device for descemet stripping automated endothelial keratoplasty. Cornea 36 (11) , pp. 1432-1436. 10.1097/ICO.0000000000001302

Okumura, Naoki, Kitahara, Miu, Okuda, Hirokazu, Hashimoto, Keisuke, Ueda, Emi, Nakahara, Makiko, Kinoshita, Shigeru, Young, Robert D., Quantock, Andrew J., Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich and Koizumi, Noriko 2017. Sustained activation of the unfolded protein response induces cell death in Fuchs' endothelial corneal dystrophy. Investigative Ophthalmology & Visual Science 58 (9) , pp. 3697-3707. 10.1167/iovs.16-21023

Akhbanbetova, Alina, Nakano, Shinichiro, Littlechild, Stacy, Young, Robert, Zvirgzdina, Madara, Fullwood, Nigel J., Weston, Ian, Weston, Philip, Kinoshita, Shigeru, Okumura, Naoki, Koizumi, Noriko and Quantock, Andrew 2017. A surgical cryoprobe for targeted transcorneal freezing and endothelial cell removal. Journal of Ophthalmology 2017 , 5614089. 10.1155/2017/5614089

Hayashi, Ryuhei, Ishikawa, Yuki, Katori, Ryousuke, Sasamoto, Yuzuru, Taniwaki, Yuki, Takayanagi, Hiroshi, Tsujikawa, Motokazu, Sekiguchi, Kiyotoshi, Quantock, Andrew J. and Nishida, Kohji 2017. Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells. Nature Protocols 12 (4) , pp. 683-696. 10.1038/nprot.2017.007

Chan, Wendy, Akhbanbetova, Alina, Quantock, Andrew J. and Heard, Charles M. 2016. Topical delivery of a Rho-kinase inhibitor to the cornea via mucoadhesive film. European Journal of Pharmaceutical Sciences 91 , pp. 256-264. 10.1016/j.ejps.2016.05.016

Hayashi, Ryuhei, Ishikawa, Yuki, Sasamoto, Yuzuru, Katori, Ryosuke, Nomura, Naoki, Ichikawa, Tatsuya, Araki, Saori, Soma, Takeshi, Kawasaki, Satoshi, Sekiguchi, Kiyotoshi, Quantock, Andrew J., Tsujikawa, Motokazu and Nishida, Kohji 2016. Co-ordinated ocular development from human iPS cells and recovery of corneal function. Nature 531 , pp. 376-380. 10.1038/nature17000

Sasamoto, Yuzuru, Hayashi, Ryuhei, Park, Sung-Joon, Saito-Adachi, Mihoko, Suzuki, Yutaka, Kawasaki, Satoshi, Quantock, Andrew J, Nakai, Kenta, Tsujikawa, Motokazu and Nishida, Kohji 2016. PAX6 isoforms, along with reprogramming factors, differentially regulate the induction of cornea-specific genes. Scientific Reports 6 , 20807. 10.1038/srep20807

Yamada, Keiko, Young, Robert David, Lewis, Philip, Shinomiya, Katsuhiko, Meek, Keith Michael Andrew, Kinoshita, S., Caterson, Bruce and Quantock, Andrew James 2015. Mesenchymal-epithelial cell interactions and proteoglycan matrix composition in the presumptive stem cell niche of the rabbit corneal limbus. Molecular Vision 21 , pp. 1328-1329.

Okumura, Naoki, Minamiyama, Ryuki, Ho, Leona TY, Kay, EunDuck P., Kawasaki, Satoshi, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich E., Young, Robert D., Quantock, Andrew J., Kinoshita, Shigeru and Koizumi, Noriko 2015. Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy. Laboratory Investigation 95 , pp. 1291-1304. 10.1038/labinvest.2015.111

Quantock, Andrew James, Winkler, Moritz, Parfitt, Geraint J, Young, Robert David, Brown, Donald J., Boote, Craig and Jester, James V. 2015. From nano to macro: Studying the hierarchical structure of the corneal extracellular matrix. Experimental Eye Research 133 , pp. 81-99. 10.1016/j.exer.2014.07.018

Ho, Leona T. Y., Harris, Anthony M., Tanioka, Hidetoshi, Yagi, Naoto, Kinoshita, Shigeru, Caterson, Bruce, Quantock, Andrew James, Young, Robert David and Meek, Keith Michael Andrew 2014. A comparison of glycosaminoglycan distributions, keratan sulphate sulphation patterns and collagen fibril architecture from central to peripheral regions of the bovine cornea. Matrix Biology 38 , pp. 59-68. 10.1016/j.matbio.2014.06.004

Forrest, Marc, Hill, Matthew J., Quantock, Andrew James, Martin-Rendon, Enca and Blake, Derek J. 2014. The emerging roles of TCF4 in disease and development. Trends in Molecular Medicine 20 (6) , pp. 322-331. 10.1016/j.molmed.2014.01.010

Young, Robert D., Knupp, Carlo, Pinali, Christian, Png, Kenneth M. Y., Ralphs, James R., Bushby, Andrew J., Starborg, Tobias, Kadler, Karl E. and Quantock, Andrew J. 2014. Three-dimensional aspects of matrix assembly by cells in the developing cornea. Proceedings of the National Academy of Sciences 111 (2) , pp. 687-692. 10.1073/pnas.1313561110

Hayes, Sally, Kamma-Lorger, Christina S., Boote, Craig, Young, Robert David, Quantock, Andrew James, Rost, Anika, Khatib, Yasmeen, Harris, Jonathan, Yagi, Naoto, Terrill, Nicholas and Meek, Keith Michael Andrew 2013. The effect of Riboflavin/UVA collagen cross-linking therapy on the structure and hydrodynamic behaviour of the ungulate and rabbit corneal stroma. PLoS ONE 8 (1) , e52860. 10.1371/journal.pone.0052860

Doutch, James J., Quantock, Andrew James, Joyce, Nancy C. and Meek, Keith Michael Andrew 2012. Ultraviolet transmission through the human corneal stroma. Biophysical Journal 102 (6) , pp. 1258-1264. 10.1016/j.bpj.2012.02.023

Koudouna, Elena, Pinali, Cristian, Young, Robert David, Palka, Barbara, Ueno, Morio, Boote, Craig, Knupp, Carlo and Quantock, Andrew James 2011. Preliminary electron microscopical studies of connective tissue in the human lamina cribrosa [Abstract]. International Journal of Experimental Pathology 92 (6) , A26. 10.1111/j.1365-2613.2011.00780.x

Khan, Ilyas Mahmood, Evans, Samuel Lewin, Young, Robert David, Blain, Emma Jane, Quantock, Andrew James, Avery, Nick and Archer, Charles William 2011. Fibroblast growth factor 2 and transforming growth factor β1 induce precocious maturation of articular cartilage. Arthritis & Rheumatism 63 (11) , pp. 3417-3427. 10.1002/art.30543

Veronesi, G., Salome, M., Fayard, B., Castillo-Michel, H., Koudouna, Elena, Quantock, Andrew James and Cotte, M. 2011. X-ray spectro-microscopy at ID21: mapping of elements and chemical states at subcellular level [Abstract]. European Biophysics Journal 40 (S1) , S130-S131. 10.1007/s00249-011-0734-z

Bushby, Andrew J., P'ng, Kenneth M. Y., Young, Robert David, Pinali, Christian, Knupp, Carlo and Quantock, Andrew James 2011. Imaging three-dimensional tissue architectures by focused ion beam scanning electron microscopy. Nature Protocols 6 (6) , pp. 845-858. 10.1038/nprot.2011.332

Parfitt, Geraint, Pinali, Christian, Akama, Tomoya O., Young, Robert David, Nishida, Kohji, Quantock, Andrew James and Knupp, Carlo 2011. Electron tomography reveals multiple self-association of chondroitin sulphate/dermatan sulphate proteoglycans in Chst5-null mouse corneas. Journal of Structural Biology 174 (3) , pp. 536-541. 10.1016/j.jsb.2011.03.015

Jones, Frances E., Hatanaka, H., Young, Robert David, Koizumi, N., Kinoshita, S., Okumura, N. and Quantock, Andrew James 2011. Investigation into endothelial cell morphology following new methods of posterior corneal surgery [Abstract]. International Journal of Experimental Pathology 92 (3) , A24. 10.1111/j.1365-2613.2010.00759.x

Tanaka, Yuji, Babac, Koichi, Duncan, Thomas, Kubota, Akira, Asahif, Toru, Quantock, Andrew, Yamatob, Masayuki, Okanob, Teruo and Nishida, Kohji 2011. Transparent, tough collagen laminates prepared by oriented flow casting, multi-cyclic vitrification and chemical cross-linking. Biomaterials 32 (13) , pp. 3358-3366. 10.1016/j.biomaterials.2010.11.011

Hayes, Sally, Boote, Craig, Kamma-Lorger, Christina S., Rajan, Madhavan S., Harris, Jonathan L., Dooley, Erin Patricia, Hawksworth, Nicholas, Hiller, Jennifer, Terill, Nick J., Hafezi, Farhad, Brahma, Arun K., Quantock, Andrew James and Meek, Keith Michael Andrew 2011. Riboflavin/UVA Collagen Cross-Linking-Induced Changes in Normal and Keratoconus Corneal Stroma. PLoS ONE 6 (8) , e22405. 10.1371/journal.pone.0022405

Young, Robert David, Liskova, P., Pinali, Cristian, Palka, Barbara Paulina, Palos, M., Jirsova, K., Hrdlickova, E., Tesarova, M., Elleder, M., Zeman, J., Meek, Keith Michael Andrew, Knupp, Carlo and Quantock, Andrew James 2011. Large Proteoglycan Complexes and Disturbed Collagen Architecture in the Corneal Extracellular Matrix of Mucopolysaccharidosis Type VII (Sly Syndrome). Investigative Ophthalmology & Visual Science 52 (9) , pp. 6720-6728. 10.1167/iovs.11-7377

Tanaka, Yuji, Kubota, Akira, Matsusaki, Michiyra, Duncan, Thomas, Hatakeyama, Yoshikiyo, Fukuyama, Katsuya, Quantock, Andrew, Yamato, Masayuki, Akashi, Mitsuru and Nishida, Kohji 2011. Anisotropic mechanical properties of collagen hydrogels induced by uniaxial-flow for ocular applications. Journal of Biomaterials Science. Polymer Edition 22 (11) , pp. 1427-1442. 10.1163/092050610X510542

Duncan, Thomas, Tanaka, Yuji, Shi, Dong, Kubota, Akira, Quantock, Andrew James and Nishida, Kohji 2010. Flow-manipulated, crosslinked collagen gels for use as corneal equivalents. Biomaterials 31 (34) , pp. 8996-9005. 10.1016/j.biomaterials.2010.08.042

Parfitt, Geraint John, Pinali, Cristian, Young, Robert David, Quantock, Andrew James and Knupp, Carlo 2010. Three-dimensional reconstruction of collagen-proteoglycan interactions in the mouse corneal stroma by electron tomography. Journal of Structural Biology 170 (2) , pp. 392-397. 10.1016/j.jsb.2010.01.019

Liles, Melody, Palka, Barbara Paulina, Harris, Anthony, Kerr, Briedgeen, Hughes, Clare Elizabeth, Young, Robert David, Meek, Keith Michael Andrew, Caterson, Bruce and Quantock, Andrew James 2010. Differential relative sulfation of keratan sulfate glycosaminoglycan in the chick cornea during embryonic development. Investigative Ophthalmology and Visual Science 51 (3) , pp. 1365-1372. 10.1167/iovs.09-4004

Lewis, Philip, Pinali, Christian, Young, Robert David, Meek, Keith Michael Andrew, Quantock, Andrew James and Knupp, Carlo 2010. Structural interactions between collagen and proteoglycans are elucidated by three-dimensional electron tomography of bovine cornea. Structure 18 (2) , pp. 239-245. 10.1016/j.str.2009.11.013

Quantock, Andrew James, Young, Robert David and Akama, Tomoya O. 2010. Structural and biochemical aspects of keratan sulphate in the cornea. Cellular and Molecular Life Sciences 67 (6) , pp. 891-906. 10.1007/s00018-009-0228-7

Palka, Barbara Paulina, Sotozono, Chie, Tanioka, Hidetoshi, Akama, Tomoya O., Yagi, Naoto, Boote, Craig, Young, Robert David, Meek, Keith Michael Andrew, Kinoshita, Shigeru and Quantock, Andrew James 2010. Structural Collagen Alterations in Macular Corneal Dystrophy Occur Mainly in the Posterior Stroma. Current Eye Research 35 (7) , pp. 580-586. 10.3109/02713681003760150

Kamma-Lorger, Christina S., Boote, Craig, Hayes, Sally, Moger, Julian, Burghammer, Manfred, Knupp, Carlo, Quantock, Andrew James, Sorensen, Thomas, Di Cola, Emanuela, White, Nicholas, Young, Robert David and Meek, Keith Michael Andrew 2010. Collagen and mature elastic fibre organisation as a function of depth in the human cornea and limbus. Journal of Structural Biology 169 (3) , pp. 424-430. 10.1016/j.jsb.2009.11.004

Palka, Barbara P., Young, Robert David, Meek, Keith Michael Andrew, Tanioka, H., Kinoshita, S., Yagi, N. and Quantock, Andrew James 2009. Depth-profiled synchrotron microbeam analysis of collagen fibril ultrastructure in the developing chick cornea [Abstract]. International Journal of Experimental Pathology 90 (2) , A126. 10.1111/j.1365-2613.2009.00644.x

Gealy, Elizabeth Claire, Hayes, Anthony Joseph, Buckwell, Rebecca, Young, Robert David, Caterson, Bruce, Quantock, Andrew James and Ralphs, James Robert 2009. Actin and type I collagen propeptide distribution in the developing chick cornea. Investigative Ophthalmology & Visual Science 50 (4) , 1653 -1658. 10.1167/iovs.08-2554

Young, Robert David, Swamynathan, S. K., Boote, Craig, Mann, M., Quantock, Andrew James, Piatigorsky, J., Funderburgh, J. L. and Meek, Keith Michael Andrew 2009. Stromal Edema in Klf4 Conditional Null Mouse Cornea Is Associated with Altered Collagen Fibril Organization and Reduced Proteoglycans. Investigative Ophthalmology & Visual Science 50 (9) , pp. 4155-4161. 10.1167/iovs.09-3561

Knupp, Carlo, Pinali, Christian, Lewis, Philip, Parfitt, Geraint John, Young, Robert David, Meek, Keith Michael Andrew and Quantock, Andrew James 2009. The architecture of the cornea and structural basis of its transparency. In: McPherson, A. ed. Advances in Protein Chemistry and Structural Biology, Vol. 78. London: Academic Press, pp. 25-49. (10.1016/S1876-1623(08)78002-7)

Doutch, James John, Quantock, Andrew James, Smith, Valerie A. and Meek, Keith Michael Andrew 2008. Light transmission in the human cornea as a function of position across the ocular surface: theoretical and experimental aspects. Biophysical Journal 95 (11) , pp. 5092-5099. 10.1529/biophysj.108.132316

Boote, Craig, Hayes, Sally, Jones, Simon, Quantock, Andrew James, Hocking, Paul M., Inglehearn, Chris F., Ali, Manir and Meek, Keith Michael Andrew 2008. Collagen organization in the chicken cornea and structural alterations in the retinopathy, globe enlarged (rge) phenotype - An X-ray diffraction study. Journal of Structural Biology 161 (1) , pp. 1-8. 10.1016/j.jsb.2007.08.015

Yamasaki, K., Kawasaki, S., Young, Robert David, Fukuoka, H., Tanioka, H., Nakatsukasa, M., Quantock, Andrew James and Kinoshita, S. 2008. Genomic Aberrations and Cellular Heterogeneity in SV40-Immortalized Human Corneal Epithelial Cells. Investigative Ophthalmology & Visual Science 50 (2) , pp. 604-613. 10.1167/iovs.08-2239

Saito, T., Nishida, K., Nakayama, J., Akama, T. O., Fukuda, M. N., Watanabe, K., Quantock, Andrew James, Maeda, N., Watanabe, H. and Tano, Y. 2008. Sulfation patterns of keratan sulfate in different macular corneal dystrophy immunophenotypes using three different probes [Letter]. British Journal of Ophthalmology 92 (10) , pp. 1434-1436. 10.1136/bjo.2008.139527

Quantock, Andrew James and Young, Robert David 2008. Development of the corneal stroma, and the collagen-proteoglycan associations that help define its structure and function. Developmental Dynamics 237 (10) , pp. 2607-2621. 10.1002/dvdy.21579

Connon, Che J., Nakamura, T., Hopkinson, A., Quantock, Andrew James, Yagi, N., Doutch, James J. and Meek, Keith Michael Andrew 2007. The biomechanics of amnion rupture: An X-Ray diffraction study. PLoS ONE 2 (11) , e1147. 10.1371/journal.pone.0001147

Young, Robert David, Gealy, Elizabeth Claire, Liles, M., Caterson, Bruce, Ralphs, James Robert and Quantock, Andrew James 2007. Keratan sulfate glycosaminoglycan and the association with collagen fibrils in rudimentary lamellae in the developing avian cornea. Investigative Ophthalmology and Visual Science 48 (7) , pp. 3083-3088. 10.1167/iovs.06-1323

Regini, Justyn Wiktor, Grossmann, J. Gunter, Timmins, Peter, Harding, John J., Quantock, Andrew James, Hodson, Stuart Arthur and Elliott, Gerald 2007. X-Ray- and Neutron-Scattering Studies of α-Crystallin and Evidence That the Target Protein Sits in the Fenestrations of the α-Crystallin Shell. Investigative Ophthalmology & Visual Science 48 (6) , pp. 2695-2700. 10.1167/iovs.06-0559

Hayes, Sally, Boote, Craig, Lewis, Jennifer, Sheppard, Jack, Abahussin, Mohammad, Quantock, Andrew James, Purslow, Christine, Votruba, Marcela and Meek, Keith Michael Andrew 2007. Comparative Study of Fibrillar Collagen Arrangement in the Corneas of Primates and Other Mammals. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology 290 (12) , pp. 1542-1550. 10.1002/ar.20613

Young, Robert David, Akama, T. O., Liskova, P., Ebenezer, N. D., Allan, B., Kerr, Briedgeen, Caterson, Bruce, Fukuda, M. N. and Quantock, Andrew James 2007. Differential immunogold localisation of sulphated and unsulphated keratan sulphate proteoglycans in normal and macular dystrophy cornea using sulphation motif-specific antibodies. Histochemistry and Cell Biology 127 (1) , pp. 115-120. 10.1007/s00418-006-0228-8

Hayes, Sally, Boote, Craig, Tuft, Stephen J., Quantock, Andrew James and Meek, Keith Michael Andrew 2007. A study of corneal thickness, shape and collagen organisation in keratoconus using videokeratography and X-ray scattering techniques. Experimental Eye Research 84 (3) , pp. 423-434. 10.1016/j.exer.2006.10.014

Doutch, James John, Quantock, Andrew James and Meek, Keith Michael Andrew 2007. Changes in visible light transmission across the corneal stroma - art. no. 65350Q. Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII 6535 , Q5350-Q5350.

Quantock, Andrew James, Boote, Craig, Young, Robert David, Hayes, Sally, Tanioka, H., Kawasaki, S., Ohta, N., Iida, T., Yagi, N., Kinoshita, S. and Meek, Keith Michael Andrew 2007. Small-angle fibre diffraction studies of corneal matrix structure: a depth profiled investigation of the human eye-bank cornea. Journal of Applied Crystallography 40 (S1) , S335-S340. 10.1107/S0021889807005523

Gealy, Elizabeth Claire, Kerr, Briedgeen, Young, Robert David, Tudor, Debbie, Hayes, Anthony Joseph, Hughes, Clare Elizabeth, Caterson, Bruce, Quantock, Andrew James and Ralphs, James Robert 2007. Differential expression of the keratan sulphate proteoglycan, keratocan, during chick corneal embryogenesis. Histochemistry and Cell Biology 128 (6) , pp. 551-555. 10.1007/s00418-007-0332-4

Hayashida, Yasutaka, Akama, Tomoya O., Beecher, Nicola, Lewis, Philip, Young, Robert David, Meek, Keith Michael Andrew, Kerr, Briedgeen, Hughes, Clare Elizabeth, Caterson, Bruce, Tanigami, Akira, Nakayama, Jun, Fukada, Michiko N., Tano, Yasuo, Nishida, Kohji and Quantock, Andrew James 2006. Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase. PNAS 103 (36) , pp. 13333-13338. 10.1073/pnas.0605441103

Young, Robert David, Quantock, Andrew James, Sotozono, C., Koizumi, N. and Kinoshita, S. 2006. Sulphation patterns of keratan sulphate proteoglycan in sclerocornea resemble cornea rather than sclera [Letter]. British Journal of Ophthalmology 90 (3) , pp. 391-393. 10.1136/bjo.2005.085803

Young, Robert David, Akama, T. O., Liskova, P., Ebenezer, N. O., Allan, B., Kerr, Briedgeen, Caterson, Bruce, Fukuda, M. N. and Quantock, Andrew James 2006. Immunogold localization of keratan sulphate in macular corneal dystrophy using monoclonal antibodies to specific sulphation motifs [Abstract]. International Journal of Experimental Pathology 87 (1) , A49-A50. 10.1111/j.0959-9673.2006.00458.x

Gealy, Elizabeth Claire, Buckwell, B., Caterson, Bruce, Quantock, Andrew James and Ralphs, James Robert 2006. Association between the cytoskeleton and collagen secretion in the developing cornea [Abstract]. International Journal of Experimental Pathology 87 (1) , A43-A44. 10.1111/j.0959-9673.2006.00458.x

Doutch, James J., Tucker, Carole, Quantock, Andrew James, Ade, Peter A. R. and Meek, Keith Michael Andrew 2006. Propagation of infrared wavelengths through the corneal stroma with reference to hydration changes. Presented at: Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII, Saratov, Russia, 26-29 September 2006. Published in: Tuchin, Valery V. ed. Saratov Fall Meeting 2006: optical technologies in biophysics and medicine VIII. Proceedings of the SPIE , vol. 6535. Bellingham, WA: SPIE, 10.1117/12.740963

Beecher, Nicola, Chakravarti, S., Joyce, S., Meek, Keith Michael Andrew and Quantock, Andrew James 2006. Neonatal development of the corneal stroma in wild-type and lumican-null mice. Investigative Ophthalmology and Visual Science 47 (1) , pp. 146-150. 10.1167/iovs.05-0907

Assiri, Abdullah Ali, Yousuf, B. I., Quantock, Andrew James and Murphy, Paul James 2005. Incidence and severity of keratoconus in Asir province, Saudi Arabia. British Journal of Ophthalmology 89 (11) , pp. 1403-1406. 10.1136/bjo.2005.074955

Beecher, N., Carlson, C., Allen, Bridget, Kipchumba, R., Conrad, G. W., Meek, Keith Michael Andrew and Quantock, Andrew James 2005. An x-ray diffraction study of corneal structure in mimecan-deficient mice. Investigative Ophthalmology and Visual Science 46 (11) , pp. 4046-4049. 10.1167/iovs.05-0325

Quantock, Andrew James, Sano, Y., Young, Robert David and Kinoshita, S. 2005. Stromal architecture and immune tolerance in additive corneal xenografts in rodents. Acta Ophthalmologica Scandinavica 83 (4) , pp. 462-466. 10.1111/j.1600-0420.2005.00509.x

Young, Robert David, Tudor, D., Hayes, Anthony Joseph, Kerr, Briedgeen, Hayashida, Y., Nishida, K., Meek, Keith Michael Andrew, Caterson, Bruce and Quantock, Andrew James 2005. Atypical composition and ultrastructure of proteoglycans in the mouse corneal stroma. Investigative Ophthalmology and Visual Science 46 (6) , pp. 1973-1978. 10.1167/iovs.04-1309

Boote, Craig, Hayes, Sally, Huang, Yifei, Quantock, Andrew James and Meek, Keith Michael Andrew 2005. Lamellar orientation in human cornea in relation to mechanical properties. Journal of Structural Biology 149 (1) , pp. 1-6. 10.1016/j.jsb.2004.08.009

Connon, Che J., Meek, Keith Michael Andrew, Kinoshita, S. and Quantock, Andrew James 2004. Spatial and temporal alterations in the collagen fibrillar array during the onset of transparency in the avian cornea. Experimental Eye Research 78 (5) , pp. 909-915. 10.1016/j.exer.2004.01.005

Connon, C. J., Kawasaki, S., Yamasaki, K., Quantock, Andrew James and Kinoshita, S. 2004. Understanding the function and location of a calcium activated chloride channel in ocular surface epithelium [Abstract]. Investigative Ophthalmology and Visual Science 45 , U388-U388.

Connon, Che J., Siegler, V., Meek, Keith Michael Andrew, Hodson, Stuart Arthur, Caterson, Bruce, Kinoshita, S. and Quantock, Andrew James 2003. Proteoglycan alterations and collagen reorganisation in the secondary avian cornea during development. Ophthalmic Research 35 (4) , pp. 177-184. 10.1159/000071168

Meek, Keith Michael Andrew, Quantock, Andrew James, Akhtar, S., Liu, C. Y. and Kao, W. 2003. Collagen fibril disorganisation in the corneas of keratocan-deficient mice as revealed by synchrotron X-ray diffraction [Abstract]. Investigative Ophthalmology and Visual Science 44 , U245-U245.

Hayes, Sally, Adachi, Wakako, Matsushima, Yoshibumi, Tachibana, Masayoshi, Boote, Craig, Meek, Keith Michael Andrew, Kinoshita, Shigeru and Quantock, Andrew James 2003. Ultrastructural Changes in Keratoconic-like Mice Corneas [Abstract]. Fibre Diffraction Review 11 , p. 135.

Quantock, Andrew James, Hayes, Sally, Adachi, Wakako, Kinoshita, Shigeru, Boote, Craig, Meek, Keith Michael Andrew, Matsushima, Yoshibumi and Tachibana, Masayoshi 2003. Annulus of collagen fibrils in mouse cornea and structural matrix alterations in a murine-specific keratopathy. Investigative Ophthalmology & Visual Science 44 (5) , pp. 1906-1911. 10.1167/iovs.02-0884

Quantock, Andrew J., Boote, Craig, Siegler, Veronique and Meek, Keith Michael Andrew 2003. Collagen organization in the secondary chick cornea during development. Investigative Ophthalmology and Visual Science 44 (1) , pp. 130-136.

Boote, Craig, Siegler, Veronique, Meek, Keith and Quantock, Andrew 2003. Collagen orientation during development of the embryonic avian cornea. Fibre Diffraction Review 11 (1) , p. 130.

Boote, Craig, Siegler, Veronique, Meek, Keith and Quantock, Andrew 2003. A wide-angle x-ray diffraction study of the developing embryonic chicken cornea. Fibre Diffraction Review 11 (1) , pp. 123-129.

Quantock, Andrew James, Boote, Craig, Siegler, Veronique and Meek, Keith Michael Andrew 2003. Collagen Organization in the Secondary Chick Cornea during Development. Investigative Ophthalmology & Visual Science 44 (1) , pp. 130-136. 10.1167/iovs.02-0544

Kostyuk, O., Nalovina, O., Mubard, T. M., Regini, Justyn Wiktor, Meek, Keith Michael Andrew, Quantock, Andrew James, Elliott, Gerald and Hodson, Stuart Arthur 2002. Transparency of the bovine corneal stroma at physiological hydration and its dependence on concentration of the ambient anion. The Journal of Physiology 543 (2) , pp. 633-642. 10.1113/jphysiol.2002.021527

Quantock, Andrew, Koizumi, Noriko and Kinoshita, Shigeru 2002. Limbal stem cell deficiencies and ocular surface reconstruction. Optometry Today 30 , pp. 27-30.

Boote, Craig, Siegler, Veronique, Meek, Keith Michael Andrew and Quantock, Andrew James 2002. Collagen orientation during development of the embryonic avian cornea [Abstract]. Investigative Ophthalmology and Visual Science 43 , E-Abstract 3214.

Quantock, Andrew James, Siegler, Veronique, Hughes, Clare Elizabeth and Caterson, Bruce 2002. Keratan sulphate levels during development of the embryonic avian cornea. Investigative Ophthalmology and Visual Science 43 (E-Abst)

Kinoshita, S., Adachi, W., Sotozono, C., Nishida, K., Yokoi, N., Quantock, Andrew James and Okubo, K. 2001. Characteristics of the human ocular surface epithelium. Progress in Retinal and Eye Research 20 (5) , pp. 639-673. 10.1016/S1350-9462(01)00007-6

Quantock, Andrew James, Meek, Keith Michael Andrew and Chakravarti, Shukti 2001. An X-ray diffraction investigation of corneal structure in lumican-deficient mice. Investigative Ophthalmology and Visual Science 42 (8) , pp. 1750-1756.

Sugita, J., Yokoi, N., Fullwood, N. J., Quantock, Andrew James, Takada, Y., Nakamura, Y. and Kinoshita, S. 2001. The detection of bacteria and bacterial biofilms in punctal plug holes. Cornea 20 (4) , pp. 362-365.