Browse by Current Cardiff authors

Bhat, Mohd Akbar, Huang, Weiran, Matsushita, Kenji, Kawashima, Rumi, Hara, Susumu, Yasukura, Yuichi, Yamaguchi, Kaito, Usui, Shinichi, Baba, Koichi, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, Kohji 2025. Transient ocular hypertension remodels astrocytes through S100B. PLoS ONE 20 (2) , e0313556. 10.1371/journal.pone.0313556

Maeno, Sayo, Lewis, Philip N. ORCID: https://orcid.org/0000-0002-3353-0708, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Oie, Yoshinori, Nishida, Kohji and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2024. Imaging pathology in archived cornea with Fuchs' endothelial corneal dystrophy including tissue reprocessing for volume electron microscopy. Scientific Reports 14 (1) , 31786. 10.1038/s41598-024-82888-5

Soma, Takeshi, Oie, Yoshinori, Takayanagi, Hiroshi, Matsubara, Shoko, Yamada, Tomomi, Nomura, Masaki, Yoshinaga, Yu, Maruyama, Kazuichi, Watanabe, Atsushi, Takashima, Kayo, Mao, Zaixing, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Hayashi, Ryuhei and Nishida, Kohji 2024. Induced pluripotent stem-cell-derived corneal epithelium for transplant surgery: a single-arm, open-label, first-in-human interventional study in Japan. The Lancet 404 (10466) , pp. 1929-1939. 10.1016/S0140-6736(24)01764-1

Howard, Laura, Ishikawa, Yuki, Katayama, Tomohiko, Park, Sung-Joon, Hill, Matthew J. ORCID: https://orcid.org/0000-0001-6776-8709, Blake, Derek J. ORCID: https://orcid.org/0000-0002-5005-4731, Nishida, Kohji, Hayashi, Ryuhei and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2024. Single-cell transcriptomics reveals the molecular basis of human iPS cell differentiation into ectodermal ocular lineages. Communications Biology 7 (1) , 1495. 10.1038/s42003-024-07130-4

Regini, Justyn W. ORCID: https://orcid.org/0000-0001-6149-5893, Yagi, Naoto, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Tanioka, Hidetoshi, Kinoshita, Shigeru, Hoshino, Masato, Uesugi, Kentaro, Meek, Keith M. ORCID: https://orcid.org/0000-0002-9948-7538, Augousti, Andy T., Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252, Pierscionek, Barbara K., Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Elliott, Gerald F. 2024. Membrane structures and functional correlates in the bi-segmented eye lens of the cephalopod. Biology Open 13 (9) , bio060445. 10.1242/bio.060445

Bu, Jinghua, Guo, Yuli, Wu, Yang, Zhang, Rongrong, Zhuang, Jingbin, Zhao, Jiankai, Sun, Le, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Liu, Zuguo and Li, Wei 2024. Models for Meibomian gland dysfunction: In vivo and in vitro. The Ocular Surface 32 , pp. 154-165. 10.1016/j.jtos.2024.03.003

Bains, Kiranjit K. ORCID: https://orcid.org/0000-0001-6617-5768, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Koudouna, Elena, Lewis, Philip N. ORCID: https://orcid.org/0000-0002-3353-0708 and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2023. Cell–cell and cell–matrix interactions at the presumptive stem cell niche of the chick corneal limbus. Cells 12 (19) , 2334. 10.3390/cells12192334

Oie, Yoshinori, Sugita, Seiichiro, Yokokura, Shunji, Nakazawa, Toru, Tomida, Daisuke, Satake, Yoshiyuki, Shimazaki, Jun, Hara, Yuko, Shiraishi, Atsushi, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Ogasawara, Takahiro, Inoie, Masukazu and Nishida, Kohji 2023. Clinical trial of autologous cultivated limbal epithelial cell sheet transplantation for patients with limbal stem cell deficiency. Ophthalmology 130 (6) , pp. 608-614. 10.1016/j.ophtha.2023.01.016

Matsushita, Kenji, Kawashima, Rumi, Hashida, Noriyasu, Hamano, Yuki, Harada, Kazuo, Higashisaka, Kazuma, Baba, Koichi, Sato, Shigeru, Huang, Weiran, Matsumoto, Hiroshi, Hamanaka, Teruhiko, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, Kohji 2023. Barium-induced toxic anterior segment syndrome. European Journal of Ophthalmology 33 (3) , NP31-NP35. 10.1177/11206721211069223

Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Ralphs, James R. ORCID: https://orcid.org/0000-0002-5367-0732 2023. Developmental changes in patterns of distribution of fibronectin and tenascin-C in the chicken cornea: evidence for distinct and independent functions during corneal development and morphogenesis. International Journal of Molecular Sciences 24 (4) , 3555. 10.3390/ijms24043555

Bains, Kiranjit K. ORCID: https://orcid.org/0000-0001-6617-5768, Ashworth, Sean, Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Hughes, Clare E. ORCID: https://orcid.org/0000-0003-4726-5877 and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2023. Chondroitin sulphate/dermatan sulphate proteoglycans: potential regulators of corneal stem/progenitor cell phenotype in vitro. International Journal of Molecular Sciences 24 (3) , 2095. 10.3390/ijms24032095

Wong, Anepmete, Fallon, Melissa, Celiksoy, Vildan, Ferla, Salvatore, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Whitaker, David ORCID: https://orcid.org/0000-0002-8271-7552, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777 2022. A composite system based upon hydroxypropyl cyclodextrins and soft hydrogel contact lenses for the delivery of therapeutic doses of econazole to the cornea, in vitro. Pharmaceutics 14 (8) , e1631. 10.3390/pharmaceutics14081631

Hashida, Noriyasu, Asao, Kazunobu, Hara, Chikako, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Saita, Ryotaro, Kurakami, Hiroyuki, Maruyama, Kazuichi and Nishida, Kohji 2022. Mitochondrial DNA as a biomarker for acute central serous chorioretinopathy: A case-control study. Frontiers in Medicine 9 , 938600. 10.3389/fmed.2022.938600

Hayashi, Ryuhei, Okubo, Toru, Kudo, Yuji, Ishikawa, Yuki, Imaizumi, Tsutomu, Suzuki, Kenji, Shibata, Shun, Katayama, Tomohiko, Park, Sung-Joon, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, Kohji 2022. Generation of 3D lacrimal gland organoids from human pluripotent stem cells. Nature 605 (7908) , pp. 126-131. 10.1038/s41586-022-04613-4

Wang, Shaopan, He, Xin, Li, Qingmin, Zhang, Yuhan, Hu, Jiaoyue, Zong, Rongrong, Zhuang, Jingyi, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Gao, Yingying, Li, Wei and Liu, Zuguo 2022. Obstructive sleep apnea affects lacrimal gland function. Investigative Ophthalmology & Visual Science 63 (3) , 3. 10.1167/iovs.63.3.3

Shiraki, Nobuhiko, Maruyama, Kazuichi, Hayashi, Ryuhei, Oguchi, Akiko, Murakawa, Yasuhiro, Katayama, Tomohiko, Takigawa, Toru, Sakimoto, Susumu, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Tsujikawa, Motokazu and Nishida, Kohji 2022. PAX6-positive microglia evolve locally in hiPSC-derived ocular organoids. Stem Cell Reports 17 (2) , pp. 221-230. 10.1016/j.stemcr.2021.12.009

Maruyama, Kazuichi, Mei, Song, Sakaguchi, Hirokazu, Hara, Chikako, Miki, Atsuya, Mao, Zaixing, Kawasaki, Ryo, Wang, Zhenguo, Sakimoto, Susumu, Hashida, Noriyasu, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Chan, Kinpui and Nishida, Kohji 2022. Diagnosis of choroidal disease with deep learning-based image enhancement and volumetric quantification of optical coherence tomography. Translational Vision Science & Technology 11 (1) , 22. 10.1167/tvst.11.1.22

Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Mikula, Eric, Brown, Donald J., Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Jester, James V. 2021. Response to letter to Editor “comments on ‘cell regulation of collagen fibril macrostructure during corneal morphogenesis’ by Koudouna et al.”. Acta Biomaterialia 136 , pp. 594-595. 10.1016/j.actbio.2021.09.061 Item availability restricted.

Lewis, Philip N. ORCID: https://orcid.org/0000-0002-3353-0708, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Souza, R. B., Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Meek, Keith M. ORCID: https://orcid.org/0000-0002-9948-7538 2021. Contrast-enhanced tissue processing of fibrillin-rich elastic fibres for 3D visualization by volume scanning electron microscopy. Methods and Protocols 4 (3) , 56. 10.3390/mps4030056

Watanabe, Shinya, Hayashi, Ryuhei, Sasamoto, Yuzuru, Tsujikawa, Motokazu, Ksander, Bruce R., Frank, Markus H., Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Frank, Natasha Y. and Nishida, Kohji 2021. Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities. iScience 24 (6) , 102688. 10.1016/j.isci.2021.102688

Nomi, Kimihito, Hayashi, Ryuhei, Ishikawa, Yuki, Kobayashi, Yuki, Katayama, Tomohiko, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, Kohji 2021. Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs. Cell Reports 34 (5) , 108715. 10.1016/j.celrep.2021.108715

Ashworth, Sean, Harrington, Jodie, Hammond, Greg M., Bains, Kiranjit K. ORCID: https://orcid.org/0000-0001-6617-5768, Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Hayes, Anthony J., Ralphs, James R. ORCID: https://orcid.org/0000-0002-5367-0732, Regini, Justyn W. ORCID: https://orcid.org/0000-0001-6149-5893, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Hayashi, Ryuhei, Nishida, Kohji, Hughes, Clare E. ORCID: https://orcid.org/0000-0003-4726-5877 and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2021. Chondroitin sulfate as a potential modulator of the stem cell niche in cornea. Frontiers in Cell and Developmental Biology 8 , 567358. 10.3389/fcell.2020.567358

Baba, Koichi, Hashida, Noriyasu, Tujikawa, Motokazu, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, Kohji 2021. The generation of fluorometholone nanocrystal eye drops, their metabolization to dihydrofluorometholone and penetration into rabbit eyes. International Journal of Pharmaceutics 592 , 120067. 10.1016/j.ijpharm.2020.120067

Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252, Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Ralphs, James R. ORCID: https://orcid.org/0000-0002-5367-0732, Ma, Yanhui, Lwigale, Peter Y., Jester, James V. and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2020. Observations on nascent matrix structures in embryonic cornea: Important in cell interactions, or merely vestiges of the lens surface? Archives of Clinical and Experimental Ophthalmology 2 (2) , pp. 67-72. 10.46439/ophthalmology.2.014

Hammond, Greg M., Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Muir, Duncan D. and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2020. The microanatomy of Bowman’s layer in the cornea of the pig: changes in collagen fibril architecture at the corneoscleral limbus. European Journal of Anatomy 24 (5) , pp. 399-406.

He, Xin, Zhao, Zhongyang, Wang, Shaopan, Kang, Jie, Zhang, Minjie, Bu, Jinghua, Cai, Xiaoxin, Jia, Changkai, Li, Yixuan, Li, Kechun, Reinach, Peter Sol, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Liu, Zuguo and Li, Wei 2020. High-fat diet-induced functional and pathologic changes in lacrimal gland. The American Journal of Pathology 190 (12) , P2387-P2402. 10.1016/j.ajpath.2020.09.002

Wang, Kehao, Hoshino, Masato, Uesugi, Kentaro, Yagi, Naoto, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Frost, Bethany E., Regini, Justyn W. ORCID: https://orcid.org/0000-0001-6149-5893, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Pierscionek, Barbara K. 2020. Cell compaction is not required for the development of gradient refractive index profiles in the embryonic chick lens. Experimental Eye Research 197 , 108112. 10.1016/j.exer.2020.108112

Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Spurlin, James, Babushkina, Anna, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Jester, James V. and Lwigale, Peter 2020. Recapitulation of normal collagen architecture in embryonic wounded corneas. Scientific Reports 10 (1) , 13815. 10.1038/s41598-020-70658-y

Kobayashi, Yuki, Hayashi, Ryuhei, Shibata, Shun, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, Kohji 2020. Ocular surface ectoderm instigated by WNT inhibition and BMP4. Stem Cell Research 46 , 101868. 10.1016/j.scr.2020.101868

Meek, Keith M. ORCID: https://orcid.org/0000-0002-9948-7538, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108 and Bell, James ORCID: https://orcid.org/0000-0001-8371-9851 2020. X-ray diffraction imaging of corneal ultrastructure. Ahearne, Mark, ed. Corneal Regeneration: Methods and Protocols, Vol. 2145. Methods in Molecular Biology, New York, NY, USA: Humana, pp. 231-247. (10.1007/978-1-0716-0599-8_16)

Baba, Koichi, Sasaki, Kei, Morita, Mio, Tanaka, Tomoyo, Teranishi, Yosuke, Ogasawara, Takahiro, Oie, Yoshinori, Kusumi, Izumi, Inoie, Masukazu, Hata, Ken-ichiro, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Kino-oka, Masahiro and Nishida, Kohji 2020. Cell jamming, stratification and p63 expression in cultivated human corneal epithelial cell sheets. Scientific Reports 10 (1) , 9282. 10.1038/s41598-020-64394-6

Wu, Yang, Wu, Jieli, Bu, Jinghua, Tang, Liying, Yang, Yiran, Ouyang, Weijie, Lin, Xiang, Liu, Zhaolin, Huang, Caihong, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Ma, Xiaoping, Li, Wei, Zhou, Yueping and Liu, Zuguo 2020. High-fat diet induces dry eye-like ocular surface damages in murine. The Ocular Surface 18 (2) , pp. 267-276. 10.1016/j.jtos.2020.02.009

Morgan, Sian R., Pilia, Nicole, Hewitt, Melissa, Moses, Rachael L., Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Lewis, Philip N. ORCID: https://orcid.org/0000-0002-3353-0708, Morrison, Peter W. J. ORCID: https://orcid.org/0000-0002-3712-7908, Kelly, Steven L., Parker, Josie E., Whitaker, David ORCID: https://orcid.org/0000-0002-8271-7552, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777 2020. Controlled in vitro delivery of voriconazole and diclofenac to the cornea using contact lenses for the treatment of Acanthamoeba keratitis. International Journal of Pharmaceutics 579 , 119102. 10.1016/j.ijpharm.2020.119102

Hewitt, Melissa G., Morrison, Peter W. J. ORCID: https://orcid.org/0000-0002-3712-7908, Boostrom, Hannah M. ORCID: https://orcid.org/0000-0002-7367-3631, Morgan, Siân R., Fallon, Melissa ORCID: https://orcid.org/0000-0002-0267-3829, Lewis, Philip N. ORCID: https://orcid.org/0000-0002-3353-0708, Whitaker, David ORCID: https://orcid.org/0000-0002-8271-7552, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Burton, Matthew J. and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777 2020. In Vitro Topical Delivery of Chlorhexidine to the Cornea: Enhancement Using Drug-Loaded Contact Lenses and β-Cyclodextrin Complexation, and the Importance of Simulating Tear Irrigation. Molecular Pharmaceutics 17 (4) , pp. 1428-1441. 10.1021/acs.molpharmaceut.0c00140

Bu, Jinghua, Yu, Jingwen, Wu, Yang, Cai, Xiaoxin, Li, Kechun, Tang, Liying, Jiang, Nan, Jeyalatha, M. Vimalin, Zhang, Minjie, Sun, Huimin, He, Hui, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Chen, Yongxiong, Liu, Zuguo and Li, Wei 2020. Hyperlipidemia affects tight junctions and pump function in the corneal endothelium. The American Journal of Pathology 190 (3) , pp. 563-576. 10.1016/j.ajpath.2019.11.008

Matsushita, Kenji, Kawashima, Rumi, Uesugi, Koji, Okada, Haruka, Sakaguchi, Hirokazu, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, Kohji 2020. Assessment of a self-assembling peptide gel, SPG-178, in providing a clear operative field for trabeculectomy surgery for glaucoma in an animal model. Scientific Reports 10 (1) , 11326. 10.1038/s41598-020-68171-3

Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252, Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Ralphs, James R. ORCID: https://orcid.org/0000-0002-5367-0732, Ma, Yanhui, Lwigale, Peter Y., Jester, James V. and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2019. Cell-independent matrix configuration in early corneal development. Experimental Eye Research 187 , 107772. 10.1016/j.exer.2019.107772

Bains, Kiranjit Kaur ORCID: https://orcid.org/0000-0001-6617-5768, Fukuoka, Hideki, Hammond, Greg M., Sotozono, Chie and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2019. Recovering vision in corneal epithelial stem cell deficient eyes. Contact Lens and Anterior Eye 42 (4) , pp. 350-358. 10.1016/j.clae.2019.04.006

Bu, Jinghua, Wu, Yang, Cai, Xiaoxin, Jiang, Nan, Jeyalatha, M. Vimalin, Yu, Jingwen, He, Xin, He, Hui, Guo, Yuli, Zhang, Mingjie, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Liu, Zuguo and Li, Wei 2019. Hyperlipidemia induces meibomian gland dysfunction. The Ocular Surface 17 (4) , pp. 777-786. 10.1016/j.jtos.2019.06.002

Hayashi, Ryuhei, Ishikawa, Yuki, Katayama, Tomohiko, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, Kohji 2018. CD200 facilitates the isolation of corneal epithelial cells derived from human pluripotent stem cells. Scientific Reports 8 (1) , 16550. 10.1038/s41598-018-34845-2

Shibata, Shun, Hayashi, Ryuhei, Okubo, Toru, Kudo, Yuji, Katayama, Tomohiko, Ishikawa, Yuki, Toga, Junko, Yagi, Emiko, Honma, Yoichi, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Sekiguchi, Kiyotoshi and Nishida, Kohji 2018. Selective laminin-directed differentiation of human induced pluripotent stem cells into distinct ocular lineages. Cell Reports 25 (6) , pp. 1668-1679. 10.1016/j.celrep.2018.10.032

Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Mikula, Eric, Brown, Donald J., Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Jester, James V. 2018. Cell regulation of collagen fibril macrostructure during corneal morphogenesis. Acta Biomaterialia 79 , pp. 96-112. 10.1016/j.actbio.2018.08.017

Morgan, Sian, Hieda, O., Nakai, Y., Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Kinoshita, S., Meek, Keith ORCID: https://orcid.org/0000-0002-9948-7538 and Quantock, Andrew ORCID: https://orcid.org/0000-0002-2484-3120 2018. Microwave treatment of the cornea leads to localised disruption of the extracellular matrix. Scientific Reports 8 , 13742. 10.1038/s41598-018-32110-0

Littlechild, Stacy, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Yoshida, H., Yamazaki, M., Sakimura, K., Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Akama, T.O. 2018. Keratan sulfate phenotype in the β-1,3-N-acetylglucosaminyltransferase-7-null mouse cornea. Investigative Ophthalmology and Visual Science 59 , pp. 1641-1651. 10.1167/iovs.17-22716

Kobayashi, Y., Hayashi, R., Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, K. 2017. Generation of a TALEN-mediated, p63 knock-in in human induced pluripotent stem cells. Stem Cell Research 25 , pp. 256-265. 10.1016/j.scr.2017.10.015

Soma, T., Koh, S., Maeda, N., Mitomo, K., Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, K. 2017. A new graft insertion device for descemet stripping automated endothelial keratoplasty. Cornea 36 (11) , pp. 1432-1436. 10.1097/ICO.0000000000001302

Okumura, Naoki, Kitahara, Miu, Okuda, Hirokazu, Hashimoto, Keisuke, Ueda, Emi, Nakahara, Makiko, Kinoshita, Shigeru, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich and Koizumi, Noriko 2017. Sustained activation of the unfolded protein response induces cell death in Fuchs' endothelial corneal dystrophy. Investigative Ophthalmology & Visual Science 58 (9) , pp. 3697-3707. 10.1167/iovs.16-21023

Akhbanbetova, Alina, Nakano, Shinichiro, Littlechild, Stacy, Young, Robert ORCID: https://orcid.org/0000-0002-8300-8002, Zvirgzdina, Madara, Fullwood, Nigel J., Weston, Ian, Weston, Philip, Kinoshita, Shigeru, Okumura, Naoki, Koizumi, Noriko and Quantock, Andrew ORCID: https://orcid.org/0000-0002-2484-3120 2017. A surgical cryoprobe for targeted transcorneal freezing and endothelial cell removal. Journal of Ophthalmology 2017 , 5614089. 10.1155/2017/5614089

Hayashi, Ryuhei, Ishikawa, Yuki, Katori, Ryousuke, Sasamoto, Yuzuru, Taniwaki, Yuki, Takayanagi, Hiroshi, Tsujikawa, Motokazu, Sekiguchi, Kiyotoshi, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, Kohji 2017. Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells. Nature Protocols 12 (4) , pp. 683-696. 10.1038/nprot.2017.007

Chan, Wendy, Akhbanbetova, Alina, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777 2016. Topical delivery of a Rho-kinase inhibitor to the cornea via mucoadhesive film. European Journal of Pharmaceutical Sciences 91 , pp. 256-264. 10.1016/j.ejps.2016.05.016

Hayashi, Ryuhei, Ishikawa, Yuki, Sasamoto, Yuzuru, Katori, Ryosuke, Nomura, Naoki, Ichikawa, Tatsuya, Araki, Saori, Soma, Takeshi, Kawasaki, Satoshi, Sekiguchi, Kiyotoshi, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Tsujikawa, Motokazu and Nishida, Kohji 2016. Co-ordinated ocular development from human iPS cells and recovery of corneal function. Nature 531 , pp. 376-380. 10.1038/nature17000

Sasamoto, Yuzuru, Hayashi, Ryuhei, Park, Sung-Joon, Saito-Adachi, Mihoko, Suzuki, Yutaka, Kawasaki, Satoshi, Quantock, Andrew J ORCID: https://orcid.org/0000-0002-2484-3120, Nakai, Kenta, Tsujikawa, Motokazu and Nishida, Kohji 2016. PAX6 isoforms, along with reprogramming factors, differentially regulate the induction of cornea-specific genes. Scientific Reports 6 , 20807. 10.1038/srep20807

Yamada, Keiko, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Lewis, Philip ORCID: https://orcid.org/0000-0002-3353-0708, Shinomiya, Katsuhiko, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Kinoshita, S., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2015. Mesenchymal-epithelial cell interactions and proteoglycan matrix composition in the presumptive stem cell niche of the rabbit corneal limbus. Molecular Vision 21 , pp. 1328-1329.

Okumura, Naoki, Minamiyama, Ryuki, Ho, Leona TY, Kay, EunDuck P., Kawasaki, Satoshi, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich E., Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Kinoshita, Shigeru and Koizumi, Noriko 2015. Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy. Laboratory Investigation 95 , pp. 1291-1304. 10.1038/labinvest.2015.111

Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Winkler, Moritz, Parfitt, Geraint J ORCID: https://orcid.org/0000-0002-8704-7906, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Brown, Donald J., Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547 and Jester, James V. 2015. From nano to macro: Studying the hierarchical structure of the corneal extracellular matrix. Experimental Eye Research 133 , pp. 81-99. 10.1016/j.exer.2014.07.018

Ho, Leona T. Y., Harris, Anthony M., Tanioka, Hidetoshi, Yagi, Naoto, Kinoshita, Shigeru, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002 and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2014. A comparison of glycosaminoglycan distributions, keratan sulphate sulphation patterns and collagen fibril architecture from central to peripheral regions of the bovine cornea. Matrix Biology 38 , pp. 59-68. 10.1016/j.matbio.2014.06.004

Forrest, Marc, Hill, Matthew J., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Martin-Rendon, Enca and Blake, Derek J. ORCID: https://orcid.org/0000-0002-5005-4731 2014. The emerging roles of TCF4 in disease and development. Trends in Molecular Medicine 20 (6) , pp. 322-331. 10.1016/j.molmed.2014.01.010

Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252, Pinali, Christian, Png, Kenneth M. Y., Ralphs, James R. ORCID: https://orcid.org/0000-0002-5367-0732, Bushby, Andrew J., Starborg, Tobias, Kadler, Karl E. and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2014. Three-dimensional aspects of matrix assembly by cells in the developing cornea. Proceedings of the National Academy of Sciences 111 (2) , pp. 687-692. 10.1073/pnas.1313561110

Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Kamma-Lorger, Christina S., Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Rost, Anika, Khatib, Yasmeen, Harris, Jonathan, Yagi, Naoto, Terrill, Nicholas and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2013. The effect of Riboflavin/UVA collagen cross-linking therapy on the structure and hydrodynamic behaviour of the ungulate and rabbit corneal stroma. PLoS ONE 8 (1) , e52860. 10.1371/journal.pone.0052860

Doutch, James J., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Joyce, Nancy C. and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2012. Ultraviolet transmission through the human corneal stroma. Biophysical Journal 102 (6) , pp. 1258-1264. 10.1016/j.bpj.2012.02.023

Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Pinali, Cristian, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Palka, Barbara, Ueno, Morio, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2011. Preliminary electron microscopical studies of connective tissue in the human lamina cribrosa [Abstract]. International Journal of Experimental Pathology 92 (6) , A26. 10.1111/j.1365-2613.2011.00780.x

Khan, Ilyas Mahmood, Evans, Samuel Lewin ORCID: https://orcid.org/0000-0003-3664-2569, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Avery, Nick and Archer, Charles William 2011. Fibroblast growth factor 2 and transforming growth factor β1 induce precocious maturation of articular cartilage. Arthritis & Rheumatism 63 (11) , pp. 3417-3427. 10.1002/art.30543

Veronesi, G., Salome, M., Fayard, B., Castillo-Michel, H., Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Cotte, M. 2011. X-ray spectro-microscopy at ID21: mapping of elements and chemical states at subcellular level [Abstract]. European Biophysics Journal 40 (S1) , S130-S131. 10.1007/s00249-011-0734-z

Bushby, Andrew J., P'ng, Kenneth M. Y., Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Pinali, Christian, Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2011. Imaging three-dimensional tissue architectures by focused ion beam scanning electron microscopy. Nature Protocols 6 (6) , pp. 845-858. 10.1038/nprot.2011.332

Parfitt, Geraint ORCID: https://orcid.org/0000-0002-8704-7906, Pinali, Christian, Akama, Tomoya O., Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Nishida, Kohji, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252 2011. Electron tomography reveals multiple self-association of chondroitin sulphate/dermatan sulphate proteoglycans in Chst5-null mouse corneas. Journal of Structural Biology 174 (3) , pp. 536-541. 10.1016/j.jsb.2011.03.015

Jones, Frances E., Hatanaka, H., Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Koizumi, N., Kinoshita, S., Okumura, N. and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2011. Investigation into endothelial cell morphology following new methods of posterior corneal surgery [Abstract]. International Journal of Experimental Pathology 92 (3) , A24. 10.1111/j.1365-2613.2010.00759.x

Tanaka, Yuji, Babac, Koichi, Duncan, Thomas, Kubota, Akira, Asahif, Toru, Quantock, Andrew ORCID: https://orcid.org/0000-0002-2484-3120, Yamatob, Masayuki, Okanob, Teruo and Nishida, Kohji 2011. Transparent, tough collagen laminates prepared by oriented flow casting, multi-cyclic vitrification and chemical cross-linking. Biomaterials 32 (13) , pp. 3358-3366. 10.1016/j.biomaterials.2010.11.011

Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Kamma-Lorger, Christina S., Rajan, Madhavan S., Harris, Jonathan L., Dooley, Erin Patricia, Hawksworth, Nicholas, Hiller, Jennifer, Terill, Nick J., Hafezi, Farhad, Brahma, Arun K., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2011. Riboflavin/UVA Collagen Cross-Linking-Induced Changes in Normal and Keratoconus Corneal Stroma. PLoS ONE 6 (8) , e22405. 10.1371/journal.pone.0022405

Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Liskova, P., Pinali, Cristian, Palka, Barbara Paulina, Palos, M., Jirsova, K., Hrdlickova, E., Tesarova, M., Elleder, M., Zeman, J., Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2011. Large Proteoglycan Complexes and Disturbed Collagen Architecture in the Corneal Extracellular Matrix of Mucopolysaccharidosis Type VII (Sly Syndrome). Investigative Ophthalmology & Visual Science 52 (9) , pp. 6720-6728. 10.1167/iovs.11-7377

Tanaka, Yuji, Kubota, Akira, Matsusaki, Michiyra, Duncan, Thomas, Hatakeyama, Yoshikiyo, Fukuyama, Katsuya, Quantock, Andrew ORCID: https://orcid.org/0000-0002-2484-3120, Yamato, Masayuki, Akashi, Mitsuru and Nishida, Kohji 2011. Anisotropic mechanical properties of collagen hydrogels induced by uniaxial-flow for ocular applications. Journal of Biomaterials Science. Polymer Edition 22 (11) , pp. 1427-1442. 10.1163/092050610X510542

Duncan, Thomas, Tanaka, Yuji, Shi, Dong, Kubota, Akira, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Nishida, Kohji 2010. Flow-manipulated, crosslinked collagen gels for use as corneal equivalents. Biomaterials 31 (34) , pp. 8996-9005. 10.1016/j.biomaterials.2010.08.042

Parfitt, Geraint John ORCID: https://orcid.org/0000-0002-8704-7906, Pinali, Cristian, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252 2010. Three-dimensional reconstruction of collagen-proteoglycan interactions in the mouse corneal stroma by electron tomography. Journal of Structural Biology 170 (2) , pp. 392-397. 10.1016/j.jsb.2010.01.019

Liles, Melody, Palka, Barbara Paulina, Harris, Anthony, Kerr, Briedgeen, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2010. Differential relative sulfation of keratan sulfate glycosaminoglycan in the chick cornea during embryonic development. Investigative Ophthalmology and Visual Science 51 (3) , pp. 1365-1372. 10.1167/iovs.09-4004

Lewis, Philip ORCID: https://orcid.org/0000-0002-3353-0708, Pinali, Christian, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252 2010. Structural interactions between collagen and proteoglycans are elucidated by three-dimensional electron tomography of bovine cornea. Structure 18 (2) , pp. 239-245. 10.1016/j.str.2009.11.013

Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002 and Akama, Tomoya O. 2010. Structural and biochemical aspects of keratan sulphate in the cornea. Cellular and Molecular Life Sciences 67 (6) , pp. 891-906. 10.1007/s00018-009-0228-7

Palka, Barbara Paulina, Sotozono, Chie, Tanioka, Hidetoshi, Akama, Tomoya O., Yagi, Naoto, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Kinoshita, Shigeru and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2010. Structural Collagen Alterations in Macular Corneal Dystrophy Occur Mainly in the Posterior Stroma. Current Eye Research 35 (7) , pp. 580-586. 10.3109/02713681003760150

Kamma-Lorger, Christina S., Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Moger, Julian, Burghammer, Manfred, Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Sorensen, Thomas, Di Cola, Emanuela, White, Nicholas, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002 and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2010. Collagen and mature elastic fibre organisation as a function of depth in the human cornea and limbus. Journal of Structural Biology 169 (3) , pp. 424-430. 10.1016/j.jsb.2009.11.004

Palka, Barbara P., Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Tanioka, H., Kinoshita, S., Yagi, N. and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2009. Depth-profiled synchrotron microbeam analysis of collagen fibril ultrastructure in the developing chick cornea [Abstract]. International Journal of Experimental Pathology 90 (2) , A126. 10.1111/j.1365-2613.2009.00644.x

Gealy, Elizabeth Claire, Hayes, Anthony Joseph, Buckwell, Rebecca, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Ralphs, James Robert ORCID: https://orcid.org/0000-0002-5367-0732 2009. Actin and type I collagen propeptide distribution in the developing chick cornea. Investigative Ophthalmology & Visual Science 50 (4) , 1653 -1658. 10.1167/iovs.08-2554

Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Swamynathan, S. K., Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Mann, M., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Piatigorsky, J., Funderburgh, J. L. and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2009. Stromal Edema in Klf4 Conditional Null Mouse Cornea Is Associated with Altered Collagen Fibril Organization and Reduced Proteoglycans. Investigative Ophthalmology & Visual Science 50 (9) , pp. 4155-4161. 10.1167/iovs.09-3561

Knupp, Carlo ORCID: https://orcid.org/0000-0001-9127-2252, Pinali, Christian, Lewis, Philip ORCID: https://orcid.org/0000-0002-3353-0708, Parfitt, Geraint John ORCID: https://orcid.org/0000-0002-8704-7906, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2009. The architecture of the cornea and structural basis of its transparency. McPherson, A., ed. Advances in Protein Chemistry and Structural Biology, Vol. 78. London: Academic Press, pp. 25-49. (10.1016/S1876-1623(08)78002-7)

Doutch, James John, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Smith, Valerie A. and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2008. Light transmission in the human cornea as a function of position across the ocular surface: theoretical and experimental aspects. Biophysical Journal 95 (11) , pp. 5092-5099. 10.1529/biophysj.108.132316

Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Jones, Simon, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Hocking, Paul M., Inglehearn, Chris F., Ali, Manir and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2008. Collagen organization in the chicken cornea and structural alterations in the retinopathy, globe enlarged (rge) phenotype - An X-ray diffraction study. Journal of Structural Biology 161 (1) , pp. 1-8. 10.1016/j.jsb.2007.08.015

Yamasaki, K., Kawasaki, S., Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Fukuoka, H., Tanioka, H., Nakatsukasa, M., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Kinoshita, S. 2008. Genomic Aberrations and Cellular Heterogeneity in SV40-Immortalized Human Corneal Epithelial Cells. Investigative Ophthalmology & Visual Science 50 (2) , pp. 604-613. 10.1167/iovs.08-2239

Saito, T., Nishida, K., Nakayama, J., Akama, T. O., Fukuda, M. N., Watanabe, K., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Maeda, N., Watanabe, H. and Tano, Y. 2008. Sulfation patterns of keratan sulfate in different macular corneal dystrophy immunophenotypes using three different probes [Letter]. British Journal of Ophthalmology 92 (10) , pp. 1434-1436. 10.1136/bjo.2008.139527

Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002 2008. Development of the corneal stroma, and the collagen-proteoglycan associations that help define its structure and function. Developmental Dynamics 237 (10) , pp. 2607-2621. 10.1002/dvdy.21579

Connon, Che J., Nakamura, T., Hopkinson, A., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Yagi, N., Doutch, James J. and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2007. The biomechanics of amnion rupture: An X-Ray diffraction study. PLoS ONE 2 (11) , e1147. 10.1371/journal.pone.0001147

Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Gealy, Elizabeth Claire, Liles, M., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Ralphs, James Robert ORCID: https://orcid.org/0000-0002-5367-0732 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2007. Keratan sulfate glycosaminoglycan and the association with collagen fibrils in rudimentary lamellae in the developing avian cornea. Investigative Ophthalmology and Visual Science 48 (7) , pp. 3083-3088. 10.1167/iovs.06-1323

Regini, Justyn Wiktor ORCID: https://orcid.org/0000-0001-6149-5893, Grossmann, J. Gunter, Timmins, Peter, Harding, John J., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Hodson, Stuart Arthur and Elliott, Gerald 2007. X-Ray- and Neutron-Scattering Studies of α-Crystallin and Evidence That the Target Protein Sits in the Fenestrations of the α-Crystallin Shell. Investigative Ophthalmology & Visual Science 48 (6) , pp. 2695-2700. 10.1167/iovs.06-0559

Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Lewis, Jennifer, Sheppard, Jack, Abahussin, Mohammad, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Purslow, Christine, Votruba, Marcela ORCID: https://orcid.org/0000-0002-7680-9135 and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2007. Comparative Study of Fibrillar Collagen Arrangement in the Corneas of Primates and Other Mammals. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology 290 (12) , pp. 1542-1550. 10.1002/ar.20613

Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Akama, T. O., Liskova, P., Ebenezer, N. D., Allan, B., Kerr, Briedgeen, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Fukuda, M. N. and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2007. Differential immunogold localisation of sulphated and unsulphated keratan sulphate proteoglycans in normal and macular dystrophy cornea using sulphation motif-specific antibodies. Histochemistry and Cell Biology 127 (1) , pp. 115-120. 10.1007/s00418-006-0228-8

Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Tuft, Stephen J., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2007. A study of corneal thickness, shape and collagen organisation in keratoconus using videokeratography and X-ray scattering techniques. Experimental Eye Research 84 (3) , pp. 423-434. 10.1016/j.exer.2006.10.014

Doutch, James John, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2007. Changes in visible light transmission across the corneal stroma - art. no. 65350Q. Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII 6535 , Q5350-Q5350.

Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Tanioka, H., Kawasaki, S., Ohta, N., Iida, T., Yagi, N., Kinoshita, S. and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2007. Small-angle fibre diffraction studies of corneal matrix structure: a depth profiled investigation of the human eye-bank cornea. Journal of Applied Crystallography 40 (S1) , S335-S340. 10.1107/S0021889807005523

Gealy, Elizabeth Claire, Kerr, Briedgeen, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Tudor, Debbie, Hayes, Anthony Joseph, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Ralphs, James Robert ORCID: https://orcid.org/0000-0002-5367-0732 2007. Differential expression of the keratan sulphate proteoglycan, keratocan, during chick corneal embryogenesis. Histochemistry and Cell Biology 128 (6) , pp. 551-555. 10.1007/s00418-007-0332-4

Hayashida, Yasutaka, Akama, Tomoya O., Beecher, Nicola, Lewis, Philip ORCID: https://orcid.org/0000-0002-3353-0708, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Kerr, Briedgeen, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Tanigami, Akira, Nakayama, Jun, Fukada, Michiko N., Tano, Yasuo, Nishida, Kohji and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2006. Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase. PNAS 103 (36) , pp. 13333-13338. 10.1073/pnas.0605441103

Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Sotozono, C., Koizumi, N. and Kinoshita, S. 2006. Sulphation patterns of keratan sulphate proteoglycan in sclerocornea resemble cornea rather than sclera [Letter]. British Journal of Ophthalmology 90 (3) , pp. 391-393. 10.1136/bjo.2005.085803

Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Akama, T. O., Liskova, P., Ebenezer, N. O., Allan, B., Kerr, Briedgeen, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Fukuda, M. N. and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2006. Immunogold localization of keratan sulphate in macular corneal dystrophy using monoclonal antibodies to specific sulphation motifs [Abstract]. International Journal of Experimental Pathology 87 (1) , A49-A50. 10.1111/j.0959-9673.2006.00458.x

Gealy, Elizabeth Claire, Buckwell, B., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Ralphs, James Robert ORCID: https://orcid.org/0000-0002-5367-0732 2006. Association between the cytoskeleton and collagen secretion in the developing cornea [Abstract]. International Journal of Experimental Pathology 87 (1) , A43-A44. 10.1111/j.0959-9673.2006.00458.x

Doutch, James J., Tucker, Carole ORCID: https://orcid.org/0000-0002-1851-3918, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Ade, Peter A. R. ORCID: https://orcid.org/0000-0002-5127-0401 and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2006. Propagation of infrared wavelengths through the corneal stroma with reference to hydration changes. Presented at: Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII, Saratov, Russia, 26-29 September 2006. Published in: Tuchin, Valery V. ed. Saratov Fall Meeting 2006: optical technologies in biophysics and medicine VIII. Proceedings of the SPIE (6535) Bellingham, WA: SPIE, 10.1117/12.740963

Beecher, Nicola, Chakravarti, S., Joyce, S., Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2006. Neonatal development of the corneal stroma in wild-type and lumican-null mice. Investigative Ophthalmology and Visual Science 47 (1) , pp. 146-150. 10.1167/iovs.05-0907

Assiri, Abdullah Ali, Yousuf, B. I., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Murphy, Paul James 2005. Incidence and severity of keratoconus in Asir province, Saudi Arabia. British Journal of Ophthalmology 89 (11) , pp. 1403-1406. 10.1136/bjo.2005.074955

Beecher, N., Carlson, C., Allen, Bridget, Kipchumba, R., Conrad, G. W., Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2005. An x-ray diffraction study of corneal structure in mimecan-deficient mice. Investigative Ophthalmology and Visual Science 46 (11) , pp. 4046-4049. 10.1167/iovs.05-0325

Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Sano, Y., Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002 and Kinoshita, S. 2005. Stromal architecture and immune tolerance in additive corneal xenografts in rodents. Acta Ophthalmologica Scandinavica 83 (4) , pp. 462-466. 10.1111/j.1600-0420.2005.00509.x

Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Tudor, D., Hayes, Anthony Joseph, Kerr, Briedgeen, Hayashida, Y., Nishida, K., Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2005. Atypical composition and ultrastructure of proteoglycans in the mouse corneal stroma. Investigative Ophthalmology and Visual Science 46 (6) , pp. 1973-1978. 10.1167/iovs.04-1309

Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Huang, Yifei, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2005. Lamellar orientation in human cornea in relation to mechanical properties. Journal of Structural Biology 149 (1) , pp. 1-6. 10.1016/j.jsb.2004.08.009

Connon, Che J., Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Kinoshita, S. and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2004. Spatial and temporal alterations in the collagen fibrillar array during the onset of transparency in the avian cornea. Experimental Eye Research 78 (5) , pp. 909-915. 10.1016/j.exer.2004.01.005

Connon, C. J., Kawasaki, S., Yamasaki, K., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Kinoshita, S. 2004. Understanding the function and location of a calcium activated chloride channel in ocular surface epithelium [Abstract]. Investigative Ophthalmology and Visual Science 45 , U388-U388.

Connon, Che J., Siegler, V., Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Hodson, Stuart Arthur, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Kinoshita, S. and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2003. Proteoglycan alterations and collagen reorganisation in the secondary avian cornea during development. Ophthalmic Research 35 (4) , pp. 177-184. 10.1159/000071168

Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Akhtar, S., Liu, C. Y. and Kao, W. 2003. Collagen fibril disorganisation in the corneas of keratocan-deficient mice as revealed by synchrotron X-ray diffraction [Abstract]. Investigative Ophthalmology and Visual Science 44 , U245-U245.

Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Adachi, Wakako, Matsushima, Yoshibumi, Tachibana, Masayoshi, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Kinoshita, Shigeru and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2003. Ultrastructural Changes in Keratoconic-like Mice Corneas [Abstract]. Fibre Diffraction Review 11 , p. 135.

Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Adachi, Wakako, Kinoshita, Shigeru, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Matsushima, Yoshibumi and Tachibana, Masayoshi 2003. Annulus of collagen fibrils in mouse cornea and structural matrix alterations in a murine-specific keratopathy. Investigative Ophthalmology & Visual Science 44 (5) , pp. 1906-1911. 10.1167/iovs.02-0884

Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Siegler, Veronique and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2003. Collagen organization in the secondary chick cornea during development. Investigative Ophthalmology and Visual Science 44 (1) , pp. 130-136.

Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Siegler, Veronique, Meek, Keith ORCID: https://orcid.org/0000-0002-9948-7538 and Quantock, Andrew ORCID: https://orcid.org/0000-0002-2484-3120 2003. Collagen orientation during development of the embryonic avian cornea. Fibre Diffraction Review 11 (1) , p. 130.

Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Siegler, Veronique, Meek, Keith ORCID: https://orcid.org/0000-0002-9948-7538 and Quantock, Andrew ORCID: https://orcid.org/0000-0002-2484-3120 2003. A wide-angle x-ray diffraction study of the developing embryonic chicken cornea. Fibre Diffraction Review 11 (1) , pp. 123-129.

Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Siegler, Veronique and Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 2003. Collagen Organization in the Secondary Chick Cornea during Development. Investigative Ophthalmology & Visual Science 44 (1) , pp. 130-136. 10.1167/iovs.02-0544

Kostyuk, O., Nalovina, O., Mubard, T. M., Regini, Justyn Wiktor ORCID: https://orcid.org/0000-0001-6149-5893, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Elliott, Gerald and Hodson, Stuart Arthur 2002. Transparency of the bovine corneal stroma at physiological hydration and its dependence on concentration of the ambient anion. The Journal of Physiology 543 (2) , pp. 633-642. 10.1113/jphysiol.2002.021527

Quantock, Andrew ORCID: https://orcid.org/0000-0002-2484-3120, Koizumi, Noriko and Kinoshita, Shigeru 2002. Limbal stem cell deficiencies and ocular surface reconstruction. Optometry Today 30 , pp. 27-30.

Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Siegler, Veronique, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2002. Collagen orientation during development of the embryonic avian cornea [Abstract]. Investigative Ophthalmology and Visual Science 43 , E-Abstract 3214.

Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Siegler, Veronique, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2002. Keratan sulphate levels during development of the embryonic avian cornea. Investigative Ophthalmology and Visual Science 43 (E-Abst)

Kinoshita, S., Adachi, W., Sotozono, C., Nishida, K., Yokoi, N., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Okubo, K. 2001. Characteristics of the human ocular surface epithelium. Progress in Retinal and Eye Research 20 (5) , pp. 639-673. 10.1016/S1350-9462(01)00007-6

Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 and Chakravarti, Shukti 2001. An X-ray diffraction investigation of corneal structure in lumican-deficient mice. Investigative Ophthalmology and Visual Science 42 (8) , pp. 1750-1756.

Sugita, J., Yokoi, N., Fullwood, N. J., Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Takada, Y., Nakamura, Y. and Kinoshita, S. 2001. The detection of bacteria and bacterial biofilms in punctal plug holes. Cornea 20 (4) , pp. 362-365.