Choorakuttil, A. J. X., Pruccoli, A., Winterhalder, M. J., Zirak, P., Gudavicius, Dominykas, Martynaitis, G., Petrulionis, D., Samsonas, D., Kontenis, L. and Zumbusch, A.
2023.
Electronically preresonant stimulated Raman scattering microscopy in the visible.
Applied Physics Letters
123
(16)
, 163701.
10.1063/5.0171725
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Abstract
We report an experimental scheme for stimulated Raman scattering (SRS) microscopy with excitation in the visible spectral region. This allows electronically preresonant (epr) SRS microscopy of a broad range of chromophores with sensitivities as low as 1 μM. Our experiment is based on two synchronously near-infrared pumped optical parametric oscillators (OPO). One of the outputs is modulated at a fourth of the repetition rate with a novel broadband electro-optical modulator. Using a combination of spectral focusing and tuning of the OPO, we show the recording of epr-SRS spectra over the whole range of molecular vibrations at a speed up to 20 times faster than classical wavelength tuning. The imaging capabilities of this setup are demonstrated with material scientific and cellular samples.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Physics and Astronomy |
| Publisher: | American Institute of Physics |
| ISSN: | 0003-6951 |
| Date of First Compliant Deposit: | 30 April 2024 |
| Date of Acceptance: | 30 September 2023 |
| Last Modified: | 30 Apr 2024 09:16 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/168487 |
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