Management of ALL in adults: 2024 ELN recommendations from a European expert panel

Gökbuget, Nicola, Boissel, Nicolas, Chiaretti, Sabina, Dombret, Hervé, Doubek, Michael, Fielding, Adele, Foà, Robin, Giebel, Sebastian, Hoelzer, Dieter, Hunault, Mathilde, Marks, David I., Martinelli, Giovanni, Ottmann, Oliver ORCID: https://orcid.org/0000-0001-9559-1330, Rijneveld, Anita, Rousselot, Philippe, Ribera, Josep and Bassan, Renato 2024. Management of ALL in adults: 2024 ELN recommendations from a European expert panel. Blood 143 (19) , pp. 1903-1930. 10.1182/blood.2023023568 Item availability restricted.

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Abstract

Abstract Experts from the European Leukemia Net (ELN) working group for adult acute lymphoblastic leukemia have identified an unmet need for guidance regarding management of adult acute lymphoblastic leukemia (ALL) from diagnosis to aftercare. The group has previously summarized their recommendations regarding diagnostic approaches, prognostic factors, and assessment of ALL. The current recommendation summarizes clinical management. It covers treatment approaches, including the use of new immunotherapies, application of minimal residual disease for treatment decisions, management of specific subgroups, and challenging treatment situations as well as late effects and supportive care. The recommendation provides guidance for physicians caring for adult patients with ALL which has to be complemented by regional expertise preferably provided by national academic study groups.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Additional Information:	License information from Publisher: LICENSE 1: URL: http://creativecommons.org/licenses/by-nc-nd/4.0/, Start Date: 2025-05-09
Publisher:	American Society of Hematology (ASH Publications)
ISSN:	0006-4971
Date of First Compliant Deposit:	13 May 2024
Date of Acceptance:	21 January 2024
Last Modified:	13 May 2024 09:15
URI:	https://orca.cardiff.ac.uk/id/eprint/168873

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