Diagnostic criteria for MOGAD

Voase, Sophie and Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 2024. Diagnostic criteria for MOGAD. Journal of Neurology 271 (6) , pp. 3690-3692. 10.1007/s00415-024-12405-1

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Abstract

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare antibody-mediated inflammatory demyelinating disorder of the central nervous system with a broad clinical spectrum. Distinct from multiple sclerosis (MS) and aquaporin-4-seropositive neuromyelitis optica spectrum disorder (AQP4-NMOSD), MOGAD can follow a monophasic or relapsing disease course and is characterised by the presence of antibodies against MOG. Until now, there had been no international consensus on diagnostic criteria for MOGAD and in this month’s journal club, we explore three recent papers on this topic. The first paper outlines the diagnostic criteria laid out by an international expert panel. The second and third papers report the retrospective systematic application of the 2023 MOGAD diagnostic criteria to regional clinic-based cohorts.

Item Type:	Article
Date Type:	Published Online
Status:	Published
Schools:	Medicine
Additional Information:	License information from Publisher: LICENSE 1: URL: http://creativecommons.org/licenses/by/4.0/, Type: open-access
Publisher:	Springer
ISSN:	0340-5354
Date of First Compliant Deposit:	31 May 2024
Date of Acceptance:	4 April 2024
Last Modified:	31 May 2024 08:45
URI:	https://orca.cardiff.ac.uk/id/eprint/169331

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