Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery.

Varghese, Oommen P., Liu, Jianping, Sundaram, Karthi, Hilborn, Jöns and Oommen, Oommen P. ORCID: https://orcid.org/0000-0003-2768-0133 2016. Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery. Biomaterials Science 4 (9) , pp. 1310-1313. 10.1039/c6bm00335d

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Abstract

Glycosaminoglycan derived nanoparticles are a promising delivery system owing to their unique tumour targeting ability. Exploiting fluorescein for inducing amphiphilicity in these biopolymers provides inherent imaging and drug stabilization capabilities by π–π stacking interactions with aromatic antineoplastic agents. This offers a versatile and highly customizable nanocarrier with narrow size distribution and high drug loading efficiency (80%) with sustained drug release.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Pharmacy
Publisher:	Royal Society of Chemistry
ISSN:	2047-4830
Date of Acceptance:	8 July 2016
Last Modified:	19 Oct 2024 01:16
URI:	https://orca.cardiff.ac.uk/id/eprint/173018

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