Low physical activity level in out-of-hospital cardiac arrest survivors with obesity, mobility problems and cognitive impairment: Results from the TTM2 trial

Heimburg, Katarina, Blennow Nordström, Erik, Dankiewicz, Josef, Friberg, Hans, Grejs, Anders M., Hänggi, Matthias, Keeble, Thomas R., Kirkegaard, Hans, Nielsen, Niklas, Rylander, Christian, Tornberg, Åsa B., Ullén, Susann, Wise, Matthew P., Cronberg, Tobias and Lilja, Gisela 2024. Low physical activity level in out-of-hospital cardiac arrest survivors with obesity, mobility problems and cognitive impairment: Results from the TTM2 trial. Resuscitation 204 , 110407. 10.1016/j.resuscitation.2024.110407

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Abstract

To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity. Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and New Zeeland were invited to a follow-up. The participants answered two questions on self-reported physical activity. Answers were categorized as a low, moderate, or high level of physical activity and further dichotomized into a low versus moderate/high level of physical activity. Potential risk factors for a low level of physical activity were collected and investigated by univariable and multivariable logistic regression. At 6 months, 807 of 939 (86%) OHCA survivors answered the two questions of physical activity; 34% reported a low, 44% moderate and 22% high level of physical activity. Obesity (OR = 1.75, 95% CI 1.10-2.77, p = 0.018), mobility problems by EuroQol 5 dimensions 5 levels (OR = 1.73, 95% CI 1.06-2.84, p = 0.029), and cognitive impairment by Symbol Digit Modalities Test (OR = 1.78, 95% CI 1.13-2.82, p = 0.013) were significantly associated with a low level of physical activity in the multivariable analysis. One third of the OHCA survivors reported a low level of physical activity. Obesity, mobility problems, and cognitive impairment were associated with a low level of physical activity. NCT02908308. [Abstract copyright: Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.]

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	Elsevier
ISSN:	0300-9572
Date of First Compliant Deposit:	21 October 2024
Date of Acceptance:	28 September 2024
Last Modified:	21 Oct 2024 14:15
URI:	https://orca.cardiff.ac.uk/id/eprint/173188

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