The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation

Kosch, Tiffany A, Torres-Sanchez, Maria, Liedtke, H Christoph, Summers, Kyle, Yun, Maximina H, Crawford, Andrew J, Maddock, Simon T, Ahammed, Md. Sabbir, Araujo, Victor L N, Bertola, Lorenzo V, Bucciarelli, Gary M, Carne, Albert, Carneiro, Celine M, Chan, Kin Onn, Chen, Ying, Crottini, Angelica, da Silva, Jessica M, Denton, Robert D, Dittrich, Carolin, Themudo, Goncalo Espregueira, Farquharson, Katherine A, Forsdick, Natalie J, Gilbert, Edward, Che, Jing, Katzenback, Barbara A, Kotharambath, Ramachandran, Levis, Nicholas A, Marquez, Roberto, Mazepa, Glib, Mulder, Kevin P, Muller, Hendrik, O'Connell, Mary J, Orozco Ter Wengel, Pablo ORCID: https://orcid.org/0000-0002-7951-4148, Palomar, Gemma, Petzold, Alice, Pfennig, David W, Pfennig, Karin S, Reichert, Michael S, Robert, Jacques, Scherz, Mark D, Siu-Ting, Karen, Snead, Anthony A, Stock, Matthias, Stuckert, Adam M M, Stynoski, Jennifer L, Tarvin, Rebecca D and Wollenberg Valero, Katharina C 2024. The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation. BMC Genomics 25 , 1025. 10.1186/s12864-024-10899-7

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Abstract

Amphibians represent a diverse group of tetrapods, marked by deep divergence times between their three systematic orders and families. Studying amphibian biology through the genomics lens increases our understanding of the features of this animal class and that of other terrestrial vertebrates. The need for amphibian genomic resources is more urgent than ever due to the increasing threats to this group. Amphibians are one of the most imperiled taxonomic groups, with approximately 41% of species threatened with extinction due to habitat loss, changes in land use patterns, disease, climate change, and their synergistic efects. Amphibian genomic resources have provided a better understanding of ontogenetic diversity, tissue regeneration, diverse life history and reproductive modes, anti-predator strategies, and resilience and adaptive responses. They also serve as essential models for studying broad genomic traits, such as evolutionary genome expansions and contractions, as they exhibit the widest range of genome sizes among all animal taxa and possess multiple mechanisms of genetic sex determination. Despite these features, genome sequencing of amphibians has signifcantly lagged behind that of other vertebrates, primarily due to the challenges of assembling their large, repeat-rich genomes and the relative lack of societal support. The emergence of long-read sequencing technologies, combined with advanced molecular and computational techniques.

Item Type:	Article
Date Type:	Published Online
Status:	Published
Schools:	Biosciences
Publisher:	BioMed Central
ISSN:	1471-2164
Date of First Compliant Deposit:	24 October 2024
Date of Acceptance:	14 October 2024
Last Modified:	04 Nov 2024 11:00
URI:	https://orca.cardiff.ac.uk/id/eprint/173311

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