Coles, Nathan T.  ORCID: https://orcid.org/0000-0001-6190-9080, Groth, Lucie J., Dettling, Lea, Frost, Daniel S., Rigo, Massimo, Neale, Samuel E. and Müller, Christian
2022.
Triple dehydrofluorination as a route to amidine-functionalized, aromatic phosphorus heterocycles.
Chemical Communications
58
(98)
, pp. 13580-13583.
10.1039/D2CC05178H
|
Preview |
PDF
- Published Version
Available under License Creative Commons Attribution Non-commercial. Download (1MB) | Preview |
Official URL: https://doi.org/10.1039/D2CC05178H
Abstract
An unexpected route to hitherto unknown amidine-functionalized phosphinines has been developed that is rapid and simple. Starting from primary amines and CF3-substituted λ3,σ2-phosphinines, a cascade of dehydrofluorination reactions leads selectively to ortho-amidinephosphinines. DFT calculations reveal that this unusual transformation can take place via a series of nucleophilic attacks at the electrophilic, low-coordinate phosphorus atom.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Chemistry |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1364-548X |
| Date of First Compliant Deposit: | 4 December 2024 |
| Date of Acceptance: | 3 November 2022 |
| Last Modified: | 04 Dec 2024 10:21 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/173576 |
Actions (repository staff only)
 |
Edit Item |
Altmetric
Altmetric