3D versus 2D systematic transrectal ultrasound-guided prostate biopsy: higher cancer detection rate in clinical practice

Peltier, Alexandre, Aoun, Fouad, El-Khoury, Fouad, Hawaux, Eric, Limani, Ksenija, Narahari, Krishna ORCID: https://orcid.org/0000-0003-0257-7033, Sirtaine, Nicolas and van Velthoven, Roland 2013. 3D versus 2D systematic transrectal ultrasound-guided prostate biopsy: higher cancer detection rate in clinical practice. Prostate Cancer 2013 (1) , 783243. 10.1155/2013/783243

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Abstract

Objectives. To compare prostate cancer detection rates of extended 2D versus 3D biopsies and to further assess the clinical impact of this method in day-to-day practice. Methods. We analyzed the data of a cohort of 220 consecutive patients with no prior history of prostate cancer who underwent an initial prostate biopsy in daily practice due to an abnormal PSA and/or DRE using, respectively, the classical 2D and the new 3D systems. All the biopsies were done by a single experienced operator using the same standardized protocol. Results. There was no significant difference in terms of age, total PSA, or prostate volume between the two groups. However, cancer detection rate was significantly higher using the 3D versus the 2D system, 50% versus 34% (P < 0.05). There was no statistically significant difference while comparing the 2 groups in term of nonsignificant cancer detection. Conclusion. There is reasonable evidence demonstrating the superiority of the 3D-guided biopsies in detecting prostate cancers that would have been missed using the 2D extended protocol.

Item Type:	Article
Status:	Published
Schools:	Medicine
Publisher:	Hindawi Publishing Corporation
ISSN:	2090-3111
Date of Acceptance:	1 October 2013
Last Modified:	19 Nov 2024 10:45
URI:	https://orca.cardiff.ac.uk/id/eprint/173978

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