Observational cohort study exploring MediEmo smartphone app use, live birth and IVF treatment return rates.

Robertson, Isla F., Harrison, China R., Morey, Richard D. ORCID: https://orcid.org/0000-0001-9220-3179, Boivin, Jacky ORCID: https://orcid.org/0000-0001-9498-1708 and Cheong, Ying 2025. Observational cohort study exploring MediEmo smartphone app use, live birth and IVF treatment return rates. F&S Reports 10.1016/j.xfre.2025.04.003

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Abstract

Objective To explore the associations between the use of the MediEmo smartphone application and IVF live birth and treatment return rates. Design A three-year observational cohort study Subjects Patients undergoing IVF were classified as users if they used the medication or emotion features of the MediEmo. Patients who did not use the two key features or declined to use the app were classified as non-users. Exposure The use of the MediEmo smartphone application. Main outcome measures Outcomes of interest were rate of live birth per fresh index cycle, live birth per complete cycle and treatment return for a stimulated cycle of treatment within 12 months of the unsuccessful stimulated index cycle. Results A total 1081 patients were eligible to use MediEmo app, 863 were categorised as users and 218 as non-users. MediEmo use was associated with a higher live birth rate per index cycle compared to non-users (27.81% [n=240/863] vs 19.26% [n=42/218], respectively, OR=1.248 95% CI: 1.041, 1.509) and treatment return rate compared to non-users (46.00% [n=169/363] vs 31.37% [n=32/102] respectively, OR=1.339 95% CI: 1.092, 1.656). It was not associated with live birth rate per complete cycle. Conclusion The observed positive association between MediEmo use and live birth and treatment return rates suggests benefits to patients and clinics. Further research and replication using a randomised controlled trial design is warranted as is investment in development of digital tools for use during IVF treatment.

Item Type:	Article
Date Type:	Published Online
Status:	In Press
Schools:	Schools > Psychology
Additional Information:	License information from Publisher: LICENSE 1: URL: http://creativecommons.org/licenses/by-nc-nd/4.0/, Start Date: 2025-04-08
Publisher:	Elsevier
ISSN:	2666-3341
Date of First Compliant Deposit:	14 April 2025
Date of Acceptance:	7 April 2025
Last Modified:	14 Apr 2025 08:45
URI:	https://orca.cardiff.ac.uk/id/eprint/177629

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