Co-occurrence of substance P-like and Leu-enkephalin-like immunoreactivities in neurones and fibres of avian nervous system [Letter]

Erichsen, Jonathan Thor ORCID: https://orcid.org/0000-0003-1545-9853, Reiner, A. and Karten, H. J. 1982. Co-occurrence of substance P-like and Leu-enkephalin-like immunoreactivities in neurones and fibres of avian nervous system [Letter]. Nature 295 (5848) , pp. 407-410. 10.1038/295407a0

Full text not available from this repository.

Abstract

Neuropeptides are frequently found in neurones that also contain another putative transmitter substance such as a biogenic amine or acetylcholine1–5. Such co-existence has led to the suggestion that the roles of neuropeptides in the nervous system may be diverse and may in some systems include a part in conventional neurotransmission as well as an ancillary, or modulatory, role. Recently, several studies have noted the co-occurrence of two peptides within individual neurones of localized regions of the mammalian nervous system6–9. Here, we present the first evidence, based on an indirect immunofluorescence technique allowing the simultaneous visualization of separate tissue antigens, that substance P (SP) and Leu-enkephalin (L-Enk) co-occur within individual neurones of widespread regions of the avian central nervous system.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Optometry and Vision Sciences
Subjects:	Q Science > QH Natural history > QH301 Biology
Publisher:	NPG
ISSN:	0028-0836
Last Modified:	18 Oct 2022 14:30
URI:	https://orca.cardiff.ac.uk/id/eprint/17783

Citation Data

Cited 101 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item