Emery, Kirsty and Eberl, Matthias ![]() |
Official URL: https://doi.org/10.1016/bs.ai.2025.05.001
Abstract
Vaccination is arguably the most effective intervention in reducing the impact of infectious diseases. However, many vaccines provide only partial or transient protection, prompting the need for more effective solutions based on our growing understanding of the pivotal role of CD4+ T follicular helper (Tfh) cells in humoral immunity and how they interact with B cells. Here we review how γδ T cells can boost antibody responses via crosstalk with both Tfh and B cells, which could lead to new adjuvant strategies to improve vaccination efficacy, achieve long-lasting protective immunity and prevent major infectious diseases of global importance.
Item Type: | Book Section |
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Date Type: | Published Online |
Status: | In Press |
Schools: | Schools > Medicine Research Institutes & Centres > Systems Immunity Research Institute (SIURI) |
Publisher: | Elsevier |
ISBN: | 978-0-443-34495-4 |
Date of First Compliant Deposit: | 27 May 2025 |
Last Modified: | 05 Jun 2025 11:15 |
URI: | https://orca.cardiff.ac.uk/id/eprint/178532 |
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