Some sage advice: A case report of sage burning causing interstitial lung disease

Ayling-Smith, Jonathan, Attanoos, Richard and Hutchinson, Nicola-Xan 2025. Some sage advice: A case report of sage burning causing interstitial lung disease. Clinical Medicine 25 (4) , 100337. 10.1016/j.clinme.2025.100337

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Abstract

Cigarette smoking remains the commonest cause of chronic obstructive pulmonary disease (COPD) and respiratory bronchiolitis-associated interstitial lung disease (RB-ILD). Biomass combustion remains a high risk for causing respiratory disease. We present a case of a 41-year-old woman and never-smoker with worsening breathlessness. It was identified that she made fire pits burning sage and oils for spiritual work, but beyond this had no respiratory risk factors. Radiological evidence of RB-ILD was identified and a bronchoscopic lavage demonstrated the presence of striking green pigmented macrophages, presumed to be chlorophyll uptake. Cessation of burning sage exposure has resulted in a positive outcome. This case highlights the need for an extensive occupational or exposure history in respiratory medicine and describes histological features of interstitial lung disease not previously identified. [Abstract copyright: Copyright © 2025 The Author(s). Published by Elsevier Ltd.. All rights reserved.]

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine
Publisher:	Royal College of Physicians
ISSN:	1473-4893
Date of First Compliant Deposit:	30 June 2025
Date of Acceptance:	1 June 2025
Last Modified:	08 Jul 2025 14:29
URI:	https://orca.cardiff.ac.uk/id/eprint/179425

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