Oyibo, Prosper  ORCID: https://orcid.org/0000-0003-4316-0883, Meulah, Brice, Agbana, Temitope, van Lieshout, Lisette, Oyibo, Wellington, Vdovine, Gleb and Diehl, Jan Carel
2025.
Deep learning-based automated detection and multiclass classification of soil-transmitted helminths and Schistosoma mansoni eggs in fecal smear images.
Scientific Reports
15
(1)
, 21495.
10.1038/s41598-025-02755-9
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Abstract
In this work, we developed an automated system for the detection and classification of soil-transmitted helminths (STH) and Schistosoma (S.) mansoni eggs in microscopic images of fecal smears. We assembled an STH and S. mansoni dataset comprising over 3,000 field-of-view (FOV) images containing parasite eggs, extracted from more than 300 fecal smear prepared using the Kato-Katz technique. These images were acquired using Schistoscope—a cost-effective automated digital microscope. After annotating the STH and S. mansoni eggs, we employed a transfer learning approach to train an EfficientDet deep learning model, using 70% of the dataset for training, 20% for validation, and 10% for testing. The developed model successfully identified STH and S. mansoni eggs in the FOV images, achieving weighted average scores of 95.9% (±1.1%) Precision, 92.1% (±3.5%) Sensitivity, 98.0 (±0.76%) Specificity, and 94.0% (±1.98%) F-Score across four classes of helminths (A. lumbricoides, T. trichiura, hookworm, and S. mansoni). Our system highlights the potential of the Schistoscope, enhanced with artificial intelligence, for detecting STH and S. mansoni infections in remote, resource-limited settings and for supporting the monitoring and evaluation of neglected tropical disease (NTD) control programs.
| Item Type: | Article |
|---|---|
| Date Type: | Published Online |
| Status: | Published |
| Schools: | Schools > Engineering |
| Subjects: | Q Science > QA Mathematics > QA75 Electronic computers. Computer science Q Science > QL Zoology R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine T Technology > TJ Mechanical engineering and machinery |
| Publisher: | Nature Research |
| ISSN: | 2045-2322 |
| Date of First Compliant Deposit: | 4 July 2025 |
| Date of Acceptance: | 15 May 2025 |
| Last Modified: | 08 Jul 2025 14:45 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/179546 |
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