Research priorities for physical activity and exercise management of people with knee and hip osteoarthritis: a multi-stage international priority-setting study from the OARSI Rehabilitation Discussion Group

Bennell, Kim L., Nelligan, Rachel K., Pardo, Jesse J., Stratulate, Sarah, Holden, Melanie A., Lawford, Belinda J., Thoma, Louise M., White, Daniel K., Wellsandt, Elizabeth, Master, Hiral, Larsen, Jesper Bie, Button, Kate ORCID: https://orcid.org/0000-0003-1073-9901, Collins, Natalie J., Skou, Søren T., Henrotin, Yves and Hinman, Rana S. 2025. Research priorities for physical activity and exercise management of people with knee and hip osteoarthritis: a multi-stage international priority-setting study from the OARSI Rehabilitation Discussion Group. Osteoarthritis and Cartilage 10.1016/j.joca.2025.07.006

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Abstract

Objective To identify research priorities for physical activity and exercise management of knee and hip osteoarthritis (OA). Design We used a multi-stage process involving an international multi-disciplinary panel of 276 experts (150 consumers, 69 clinicians spanning 5 disciplines, 54 researchers, and 3 funder/consumer organisation representatives) from 26 countries. The process included: 1) compiling a list of unanswered research questions from existing research; 2) assembling the panel and generating additional questions from members via an online survey; 3) consolidating research questions (eg. removing duplicates); 4) scoring questions for priority by the panel on an 11-point numeric rating scale (0=‘not a priority at all; 10=‘highest priority’) via another online survey; and 5) ranking the top 20 priority questions by the panel via an online discrete choice experiment (1000Minds). Results A list of 61 research questions was compiled from the literature and the panel generated an additional 346 questions. Following consolidation, 178 questions remained and were scored by 150 of the original panelists (54%), with mean priority scores from 5.0 to 8.4. 153 (55%) panelists completed the discrete choice experiment. The top three research priorities were: 1) investigating the impact of physical activity and exercise on delaying/avoiding joint replacement, 2) developing effective interventions to promote long-term exercise adherence, and 3) stratifying people to the most appropriate form of exercise support. Conclusion We identified research priorities about physical activity and exercise management of knee and hip OA. These will guide the international research agenda with the aim of improving outcomes for people with OA.

Item Type:	Article
Date Type:	Published Online
Status:	In Press
Schools:	Schools > Healthcare Sciences
Additional Information:	License information from Publisher: LICENSE 1: Title: This article is under embargo with an end date yet to be finalised.
Publisher:	Elsevier
ISSN:	1063-4584
Date of First Compliant Deposit:	17 July 2025
Date of Acceptance:	4 July 2025
Last Modified:	17 Jul 2025 09:00
URI:	https://orca.cardiff.ac.uk/id/eprint/179883

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