Establishing the content validity of a stroke specific Patient Reported Outcome Measure (PROM) in people living with stroke: a mixed methods content validity study

Gething, Stephanie 2025. Establishing the content validity of a stroke specific Patient Reported Outcome Measure (PROM) in people living with stroke: a mixed methods content validity study. Cardiff University. Item availability restricted.

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Abstract

Introduction: A stroke-specific 15-item Patient Reported Outcome Measure (PROM) has been recommended by the International Consortium for Health Outcomes Measurement (ICHOM) to measure health-related quality of life (HRQoL) in people living with stroke, as part of a standard set of stroke outcome measures. The PROM-15 has not been validated in this population. This study aimed to establish the content validity of the PROM-15 in people living with stroke, using the evidence-based COnsensus‐based Standards for the selection of health Measurement INstruments (COSMIN) methodology. Method: A mixed-methods, convergent study design was employed. A purposive sample was recruited of six people living with stroke, two informal carers and eight Health Care Professionals (HCPs) specialising in stroke in South Wales. The HCPs completed an on-line survey to rate the relevance of the PROM-15’s items to people living with stroke. Cognitive interviews were carried out with patients with stroke and their informal carers, to elicit their views on the comprehensibility, comprehensiveness and relevance of the PROM-15’s items to HRQoL following a stroke. Analysis of the survey data employed the Content Validity Index (CVI) and thematic analysis was carried out on the interview data and survey free-text comments. The results were integrated for final analysis. Results: The Scale CVI for the PROM-15 indicated excellent content validity (S- CVI/Ave=0.96/0.1). Deductive thematic analysis found that the PROM-15 met the COSMIN criteria for content validity. Integration of the findings indicated that the PROM-15 demonstrates content validity in this study sample, with complementarity across data sets. Conclusion: This study provides supporting evidence that the PROM-15 has satisfactory content validity to measure HRQoL in people living with stroke. Results are limited to a small sample of patients with minimal post-stroke impairments, their informal carers and HCPs. Further psychometric testing of the PROM- 15 with a larger, more diverse sample is recommended.

Item Type:	Thesis (Other)
Date Type:	Completion
Status:	Unpublished
Schools:	Schools > Healthcare Sciences
Date of First Compliant Deposit:	17 July 2025
Last Modified:	17 Jul 2025 15:48
URI:	https://orca.cardiff.ac.uk/id/eprint/179903

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