Perinatal mood episodes in fathers with bipolar disorder.

Brooks, Ruth, Marsden, Jemima, Mahoney, Berenice, Perry, Amy, Jones, Ian ORCID: https://orcid.org/0000-0001-5821-5889, Gordon-Smith, Katherine and Jones, Lisa 2025. Perinatal mood episodes in fathers with bipolar disorder. Journal of Affective Disorders 390 , 119856. 10.1016/j.jad.2025.119856

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Abstract

No published research into perinatal mood episodes (PMEs) among fathers with bipolar disorder (BD) exists despite the perinatal period being a time of high-risk for mothers with BD. This study aims to determine the frequency, polarity and timing of onset of PMEs in a large sample of fathers with BD. Data on PMEs were collected from 196 fathers with a DSM diagnosis of BD. Participants were asked via a self-report questionnaire about the occurrence, type and timing of PMEs during pregnancy up to 6 months postpartum. Findings were compared to data on PMEs collected from mothers with BD using the same method (n = 597). 36.2 % of fathers with BD reported experiencing PMEs, with similar proportions reporting depression and high/mixed mood/psychosis (17 % and 18.6 % respectively). Episode onset was most common during pregnancy (41.9 %) (compared to within 1-week, 1 to 6-weeks, and 6 weeks to 6 months postpartum respectively). Rate of PME in mothers was higher (73.0 %), with high/mixed mood/psychosis more common than depression (44.5 % v 28.1 %), and most common onset within 1-week postpartum (41.3 %). Rates of paternal PMEs in BD in this study are likely inflated due to methodology. PMEs were commonly reported among fathers with BD. Fathers do not undergo the same biological changes as mothers during the perinatal period which may partly explain the different patterns observed in the type and timings of PMEs between fathers and mothers with BD. Prospective longitudinal studies are needed to explore specific potential risk factors. [Abstract copyright: Copyright © 2025 The Authors. Published by Elsevier B.V. All rights reserved.]

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine
Publisher:	Elsevier
ISSN:	0165-0327
Date of First Compliant Deposit:	30 July 2025
Date of Acceptance:	7 July 2025
Last Modified:	30 Jul 2025 09:30
URI:	https://orca.cardiff.ac.uk/id/eprint/180132

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