Lewis, Sam G., Warren, Mark R. and Hatcher, Lauren E.  ORCID: https://orcid.org/0000-0002-1549-9727
2025.
The impact of x‐ray damage in chemical crystalline materials and new opportunities for small molecule serial crystallography.
Chemistry - A European Journal
, e01711.
10.1002/chem.202501711
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Abstract
In line with the dramatic and continuing improvements in X‐ray generation technologies for laboratory and accelerator sources around the world, reports of X‐ray‐induced processes in chemical crystalline materials are on the rise. These observations are challenging the traditional viewpoint that radiation damage is only of significant concern for protein structure determinations, encouraging small molecule crystallographers to identify and address X‐ray‐induced effects in a broadening range of susceptible materials. This review explores the recent investigations into X‐ray damage and X‐ray‐induced transformations in chemical crystalline materials and discusses state‐of‐the‐art methodologies to quantify and mitigate the effects of the X‐ray probe on single‐crystal and microcrystalline powder samples.
| Item Type: | Article |
|---|---|
| Date Type: | Published Online |
| Status: | In Press |
| Schools: | Schools > Chemistry |
| Additional Information: | License information from Publisher: LICENSE 1: URL: http://creativecommons.org/licenses/by/4.0/ |
| Publisher: | Wiley |
| ISSN: | 0947-6539 |
| Date of First Compliant Deposit: | 3 September 2025 |
| Date of Acceptance: | 8 July 2025 |
| Last Modified: | 16 Sep 2025 13:40 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/180227 |
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