Human induced pluripotent stem cell-derived microglia with 1q21.1 deletion and duplication exhibit aberrant inflammatory response

Singh, Tanya, Trabzonlu, Kubra, Spasova, Aleksandra, Stephens, Phil ORCID: https://orcid.org/0000-0002-0840-4996, Linden, David E. J. ORCID: https://orcid.org/0000-0002-5638-9292, van den Bree, Marianne B. M. ORCID: https://orcid.org/0000-0002-4426-3254, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Neogi, Ujjwal, Harwood, Adrian J. ORCID: https://orcid.org/0000-0003-3124-5169 and Syed, Yasir Ahmed ORCID: https://orcid.org/0000-0001-9495-307X 2026. Human induced pluripotent stem cell-derived microglia with 1q21.1 deletion and duplication exhibit aberrant inflammatory response. Genes & diseases 13 (4) , 101923. 10.1016/j.gendis.2025.101923

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Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Biosciences Schools > Dentistry Schools > Medicine
Publisher:	Elsevier
ISSN:	2352-4820
Funders:	Wellcome Trust, Medical Research Council
Projects:	DEFINE Strategic Award 00202/Z/12/Z, 226709/Z/22Z, MR/L010305/1, MR/NO22572/1, MR/L011166/1, MR/W014416/1, MR/ W028395/1, MR/W020297/1, MR/T033045/1, MR/S037667/ 1
Date of First Compliant Deposit:	9 October 2025
Date of Acceptance:	8 October 2025
Last Modified:	17 Jun 2026 21:53
URI:	https://orca.cardiff.ac.uk/id/eprint/181572

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