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Number of items: 48.

Robinson, Jessica, Uzun, Orhan, Ron Loh, Ne, Harris, Isabelle Rose, Woolley, Thomas E., Harwood, Adrian, Gardner, Jennifer Frances and Syed, Yasir Ahmed 2022. The association of neurodevelopmental abnormalities, congenital heart and renal defects in a Tuberous Sclerosis Complex patient cohort. BMC Medicine 20 , 123. 10.1186/s12916-022-02325-0

Chapman, Gareth, Alsaqati, Mouhamed, Lunn, Sharna, Singh, Tanya, Linden, Stephanie C., Linden, David E.J., van den Bree, Marianne B. V., Ziller, Mike, Owen, Michael J., Hall, Jeremy, Harwood, Adrian J. and Syed, Yasir Ahmed 2022. Using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion and duplication syndrome. Molecular Psychiatry 27 , pp. 819-830. 10.1038/s41380-021-01182-2

Stewart, Balint, Gruenheit, Nicole, Baldwin, Amy, Chisholm, Rex, Rozen, Daniel, Harwood, Adrian, Wolf, Jason B. and Thompson, Christopher R. L. 2022. The genetic architecture underlying prey-dependent performance in a microbial predator. Nature Communications 13 (1) , 319. 10.1038/s41467-021-27844-x

Sanders, Bret, D'Andrea, Daniel, Collins, Mark O., Rees, Elliott, Steward, Tom G. J., Zhu, Ying, Chapman, Gareth, Legge, Sophie E., Pardinas, Antonio F., Harwood, Adrian J., Gray, William P., O'Donovan, Michael C., Owen, Michael J., Errington, Adam C., Blake, Derek J., Whitcomb, Daniel J., Pocklington, Andrew J. and Shin, Eunju 2022. Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants. Nature Communications 13 (1) , 27. 10.1038/s41467-021-27601-0

Gruenheit, Nicole, Baldwin, Amy, Stewart, Balint, Jaques, Sarah, Keller, Thomas, Parkinson, Katie, Salvidge, William, Baines, Robert, Brimson, Chris, Wolf, Jason B., Chisholm, Rex, Harwood, Adrian J. and Thompson, Christopher R. L. 2021. Mutant resources for functional genomics in Dictyostelium discoideum using REMI-seq technology. BMC Biology 19 (1) , 172. 10.1186/s12915-021-01108-y

Oliva-Teles, Natália, de Stefano, Maria Chiara, Gallagher, Louise, Rakic, Severin, Jorge, Paula, Cuturilo, Goran, Markovska-Simoska, Silvana, Borg, Isabella, Wolstencroft, Jeanne, Tümer, Zeynep, Harwood, Adrian J., Kodra, Yllka and Skuse, David 2020. Rare pathogenic copy number variation in the 16p11.2 (BP4–BP5) region associated with neurodevelopmental and neuropsychiatric disorders: a review of the literature. International Journal of Environmental Research and Public Health 17 (24) , 9253. 10.3390/ijerph17249253

Alsaqati, Mouhamed, Heine, Vivi M. and Harwood, Adrian J. 2020. Pharmacological intervention to restore connectivity deficits of neuronal networks derived from ASD patient iPSC with a TSC2 mutation. Molecular Autism 11 , 80. 10.1186/s13229-020-00391-w

Davis, Brittany, David, Francois, O’Regan, Ciara, Adam, Manal, Harwood, Adrian, Crunelli, Vincenzo and Isles, Anthony 2020. Impairments in sensory-motor gating and information processing in a mouse model of Ehmt1 haploinsufficiency. Brain and Neuroscience Advances 4 10.1177/2398212820928647

Drakulic, Danijela, Djurovic, Srdjan, Syed, Yasir Ahmed, Trattaro, Sebastiano, Caporale, Nicolò, Falk, Anna, Ofir, Rivka, Heine, Vivi M., Chawner, Samuel J. R. A., Rodriguez-Moreno, Antonio, van den Bree, Marianne B. M., Testa, Giuseppe, Petrakis, Spyros and Harwood, Adrian J. 2020. Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD. Molecular Autism 11 (1) , 42. 10.1186/s13229-020-00343-4

Perry, Christopher J., Finch, Paul, Müller-Taubenberger, Annette, Leung, Kit-Yi, Warren, Eleanor C., Damstra-Oddy, Joseph, Sharma, Devdutt, Patra, Pabitra H., Glyn, Sarah, Boberska, Joanna, Stewart, Balint, Baldwin, Amy, Piscitelli, Fabiana, Harvey, Robert J., Harwood, Adrian, Thompson, Christopher, Claus, Sandrine P., Greene, Nicholas D. E., McNeish, Alister J., Williams, Claire M., Whalley, Benjamin J. and Williams, Robin S. B. 2020. A new mechanism for cannabidiol in regulating the one-carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models. British Journal of Pharmacology 177 (4) , pp. 912-928. 10.1111/bph.14892

Plumbly, William, Brandon, Nick, Deeb, Tarek Z., Hall, Jeremy and Harwood, Adrian J. 2019. L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks. Scientific Reports 9 , 13810. 10.1038/s41598-019-50226-9

Harwood, Janet C., Kent, Nicholas A., Allen, Nicholas D. and Harwood, Adrian J. 2019. Nucleosome dynamics of human iPSC during neural differentiation. EMBO reports 20 (6) , e46960. 10.15252/embr.201846960

Nadadhur, Aishwarya G., Alsaqati, Mouhamed, Gasparotto, Lisa, Cornelissen-Steijger, Paulien, van Hugte, Eline, Dooves, Stephanie, Harwood, Adrian J. and Heine, Vivi M. 2019. Neuron-glia interactions increase neuronal phenotypes in tuberous sclerosis complex patient iPSC-derived models. Stem Cell Reports 12 (1) , pp. 42-56. 10.1016/j.stemcr.2018.11.019

Harwood, Adrian and Baldwin, Amy 2018. Dictyostelium. Encyclopedia of Microbiology (Fourth Edition), Elsevier, pp. 18-27. (10.1016/B978-0-12-809633-8.13033-X)

Cocorocchio, Marco, Baldwin, Amy, Stewart, Balint, Kim, Lou, Harwood, Adrian, Thompson, Christopher R. L., Andrews, Paul L. R. and Williams, Robin S. B. 2018. Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum. Disease Models & Mechanisms 11 , 032375. 10.1242/dmm.032375

Platt, James L., Kent, Nicholas A., Kimmel, Alan R. and Harwood, Adrian J. 2017. Regulation of nucleosome positioning by a CHD Type III chromatin remodeler and its relationship to developmental gene expression in Dictyostelium. Genome Research 27 , pp. 591-600. 10.1101/gr.216309.116

Falk, A, Heine, V M, Harwood, Adrian John, Sullivan, P F, Peitz, M, Brüstle, O, Shen, S, Sun, Y-M, Glover, J C, Posthuma, D and Djurovic, S 2016. Modeling psychiatric disorders: from genomic findings to cellular phenotypes. Molecular Psychiatry 21 (9) , pp. 1167-1179. 10.1038/mp.2016.89

Tarrés, Màrius, Canetta, Elisabetta, Paul, Eleanor, Forbes, Jordan, Azzouni, Karima, Viñas, Clara, Teixidor, Francesc and Harwood, Adrian J. 2015. Biological interaction of living cells with COSAN-based synthetic vesicles. Scientific Reports 5 , 7804. 10.1038/srep07804

Tarrés, Màrius, Canetta, Elisabetta, Viñas, Clara, Teixidor, Francesc and Harwood, Adrian John 2014. Imaging in living cells using νB–H Raman spectroscopy: monitoring COSAN uptake. Chemical Communications 50 (25) , pp. 3370-3372. 10.1039/c3cc49658a

Platt, James Louis, Rogers, Benjamin James, Rogers, Kelley C., Harwood, Adrian John and Kimmel, Alan R. 2013. Different CHD chromatin remodelers are required for expression of distinct gene sets and specific stages during development of Dictyostelium discoideum. Development 140 (24) , pp. 4926-4936. 10.1242/dev.099879

Harwood, Adrian John, Forde -Thomas, Josephine, Williams, Hazel, Samereier, Matthias and Müller-Taubenberger, Annette 2013. Aberrant spindle dynamics and cytokinesis in Dictyostelium discoideum cells that lack glycogen synthase kinase 3. European Journal of Cell Biology 92 (6-7) , pp. 222-228. 10.1016/j.ejcb.2013.05.001

Fox, Michael A., Kreis, Patricia, Hendricusdottir, Rita, Kay, Louise, Papageorgiou, Ismini E., van Diepen, Michiel, Mack, Till, Ryves, Jonny, Harwood, Adrian John, Leslie, Nicholas R., Kann, Oliver, Parsons, Maddy and Eickholt, Britta J. 2013. Phosphorylation of the Actin Binding Protein Drebrin at S647 Is Regulated by Neuronal Activity and PTEN. PLoS ONE 8 (8) , e71957. 10.1371/journal.pone.0071957

Harwood, Adrian John 2011. Prolyl oligopeptidase, inositol phosphate signalling and lithium sensitivity. CNS & Neurological Disorders - Drug Targets 10 (3) , pp. 333-339. 10.2174/187152711794653779

Perrins, Richard D., Orchard, Craig B., Zavodszky, Maria, Kasry, Amal, Nikolaev, Nikolay, Harwood, Adrian John, Borri, Paola and Dale, Trevor Clive 2011. Doing more with less: a method for low total mass, affinity measurement using variable-length nanotethers. Analytical Chemistry 83 (23) , pp. 8900-8905. 10.1021/ac2012569

Teo, Regina Mei Mei, Lewis, Kimberley, Forde, Josephine E., Ryves, William Jonathan, Reddy, Jonathan Venkat, Rogers, Benjamin James and Harwood, Adrian John 2010. Glycogen synthase kinase-3 is required for efficient 'Dictyostelium' chemotaxis. Molecular Biology of the Cell 21 (15) , pp. 2788-2796. 10.1091/mbc.E09-10-0891

King, Jason, Keim, Melanie, Teo, Regina, Weening, Karin Esther, Kapur, Mridu, McQuillan, Karina, Ryves, William Jonathan, Rogers, Benjamin James, Dalton, Emma Charlotte, Williams, Robin S. B. and Harwood, Adrian John 2010. Genetic control of lithium sensitivity and regulation of inositol biosynthetic genes. PLoS ONE 5 (6) , e11151. 10.1371/journal.pone.0011151

Rey, Sara M., Harwood, Adrian John, Povazay, Boris, Hofer, Bernd, Unterhuber, Angelika and Drexler, Wolfgang 2010. Mutant and wild type cell chemotaxis in 3D and 4D with ultrahigh- resolution optical coherence tomography. Presented at: Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV, San Francisco, CA, USA, 25-27 January 2010. Published in: Izatt, Joseph A., Fujimoto, James G. and Tuchin, Valery V. eds. Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV. Proceedings of SPIE , vol. 7554. Bellingham, WA: SPIE, pp. 505-509. 10.1117/12.843244

Kasry, Amal, Borri, Paola, Davies, Philip Rosser, Harwood, Adrian John, Thomas, Nick, Lofas, Stefan and Dale, Trevor Clive 2009. Comparison of methods for generating planar DNA-modified surfaces for hybridization studies. ACS Applied Materials & Interfaces 1 (8) , pp. 1793-1798. 10.1021/am9003073

Rey, Sara Maria, Považay, Boris, Hofer, Bernd, Unterhuber, A., Hermann, Boris, Harwood, Adrian John and Drexler, Wolfgang 2009. Three- and four-dimensional visualization of cell migration using optical coherence tomography. Journal of Biophotonics 2 (6-7) , pp. 370-379. 10.1002/jbio.200910027

Rey, Sara Maria, Harwood, Adrian John, Povazay, Boris, Hofer, Bernd, Unterhuber, Angelika, Hermann, Boris and Drexler, Wolfgang 2009. Visualization of 3D cell migration using high speed ultrahigh resolution optical coherence tomography. Presented at: Optics in tissue engineering and regenerative medicine III, San Jose, CA, USA, 24 January 2009. Published in: Kirkpatrick, Sean J. and Wang, Ruikang eds. Optics in Tissue Engineering and Regenerative Medicine III, 24 January 2009, San Jose, CA, USA. Proceedings of SPIE , vol. 7179. Bellingham, WA: SPIE - International Society for Optical Engineering, pp. 505-509. 10.1117/12.809178

Shimshoni, J. A., Dalton, Emma Charlotte, Watson, Peter Duncan, Yagen, B., Bialer, M. and Harwood, Adrian John 2009. Evaluation of the effects of propylisopropylacetic acid (PIA) on neuronal growth cone morphology. Neuropharmacology 56 (4) , pp. 831-837. 10.1016/j.neuropharm.2009.01.014

King, Jason, Teo, Regina, Ryves, William Jonathan, Reddy, Jonathan Venkat, Peters, Owen Morgan, Orabi, Ben, Hoeller, Oliver, Williams, Robin S. B. and Harwood, Adrian John 2009. The mood stabiliser lithium suppresses PIP3 signalling in 'Dictyostelium' and human cells. Disease Models & Mechanisms 2 (5-6) , pp. 306-312. 10.1242/dmm.001271

Teo, Regina Mei Mei, King, J., Dalton, Emma Charlotte, Ryves, William Jonathan, Harwood, Adrian John and Williams, R. S. B. 2009. Ptdins (3,4,5)P-3 and inositol depletion as a cellular target of mood stabilizers. Biochemical Society Transactions 37 (5) , pp. 1110-1114. 10.1042/BST0371110

Peineau, Stéphane, Nicolas, Céline, Bortolotto, Zuner, Bhat, Ratan, Ryves, William Jonathan, Harwood, Adrian John, Dournaud, Pascal, Fitzjohn, Stephen and Collingridge, Graham 2009. A systematic investigation of the protein kinases involved in NMDA receptor-dependent LTD: evidence for a role of GSK-3 but not other serine/threonine kinases. Molecular Brain 2 (1) , 22. 10.1186/1756-6606-2-22

Cho, Jalesoon, King, Jason, Qian, Xun, Harwood, Adrian John and Shears, Stephen B. 2008. Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt. Proceedings of the National Academy of Sciences of the United States of America 105 (16) , pp. 5998-6003. 10.1073/pnas.0710980105

Harwood, Adrian John 2008. Dictyostelium development: a prototypic Wnt pathway? In: Vincan, E. ed. Wnt Signaling, Vol. 2. Methods in Molecular Biology, vol. 469. New York, NY: Humana Press, pp. 21-32. (10.1007/978-1-60327-469-2_2)

Harwood, Adrian John 2008. Monitoring patterns of gene expression in Dictyostelium by beta-galacotsidase staining. In: Vincan, E. ed. Wnt signaling- Pathway models, Vol. 2. Methods in Molecular Biology, vol. 469. Totowa, N.J.: Humana, pp. 33-37.

Harwood, Adrian John 2008. Use of the Dictyostelium stalk cell assay to monitor GSK-3 regulation. In: Vincan, Elizabeth ed. Wnt Signaling, Vol. 469. Methods in Molecular Biology, Springer, pp. 39-43. (10.1007/978-1-60327-469-2_4)

University College Cardiff Consultants, Ltd. 2008. Method of measuring the affinity of biomolecules. EP1949104A2. [Patent].

Shaltiel, Galit, Dalton, Emma Charlotte, Belmaker, Robert H., Harwood, Adrian John and Agam, Galila 2007. Specificity of mood stabilizer action on neuronal growth cones. Bipolar Disorders 9 (3) , pp. 281-289. 10.1111/j.1399-5618.2007.00400.x

Strmecki, L., Bloomfield, G., Araki, T., Dalton, Emma Charlotte, Skelton, J., Schilde, C., Harwood, Adrian John, Williams, J. G., Ivens, A. and Pears, C. 2007. Proteomic and microarray analyses of the Dictyostelium Zak1-GSK-3 signaling pathway reveal a role in early development. Eukaryotic Cell 6 (2) , pp. 245-252. 10.1128/EC.00204-06

Shimshoni, J. A., Dalton, Emma Charlotte, Jenkins, A., Eyal, S., Ewan, Kenneth Burnside Ramsay, Williams, R. S. B., Pessah, N., Yagen, B., Harwood, Adrian John and Bialer, M. 2006. The effects of central nervous system-active valproic acid constitutional isomers, cyclopropyl analogs, and amide derivatives on neuronal growth cone behavior. Molecular Pharmacology 71 (3) , pp. 884-892. 10.1124/mol.106.030601

Ryves, William Jonathan, Dalton, Emma Charlotte, Harwood, Adrian John and Williams, Robin S. B. 2005. GSK-3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid. Bipolar Disorders , pp. 260-265. 10.1111/j.1399-5618.2005.00194.x

Schilde, Christina, Araki, Tsuyoshi, Williams, Hazel, Harwood, Adrian John and Williams, Jeffrey G. 2004. GSK-3 is a multi-functional regulator of Dictyostelium development. Development 131 (18) , pp. 4555-4565. 10.1242/dev.01330

Harwood, Adrian John, Kim, L. and Kimmel, A.R. 2002. Receptor-dependent and tyrosine phosphatase-mediated inhibition of GSK3 regulates cell fate choice. Developmental Cell , pp. 523-532. 10.1016/S1534-5807(02)00269-1

Williams, Robin S. B., Cheng, Lili, Mudge, Anne W. and Harwood, Adrian John 2002. A common mechanism of action for three mood-stabilizing drugs. Nature , pp. 292-295. 10.1038/417292a

Fraser, Elizabeth, Young, N., Dajani, R., Franca-Koh, J., Ryves, William Jonathan, Williams, R. S. B., Yeo, M., Webster, M.-T., Richardson, C., Smalley, Matthew John, Pearl, L. H., Harwood, Adrian John and Dale, Trevor Clive 2002. Identification of the Axin and Frat binding region of glycogen synthase kinase-3. Journal of Biological Chemistry 277 (3) , pp. 2176-2185. 10.1074/jbc.M109462200

Williams, Robin S. B., Cheng, Lili, Mudge, Anne W. and Harwood, Adrian 2002. A common mechanism of action for three mood stabilizing drugs. Nature 417 (6886) , pp. 292-295. 10.1038/417292a

This list was generated on Thu Sep 29 04:20:18 2022 BST.