Harwood, Adrian J. ORCID: https://orcid.org/0000-0003-3124-5169, Petrakis, Spyros, Oktay, Yavuz and Pasterkamp, R. Jeroen 2023. Editorial: Mental health: cell models to mechanisms. Frontiers in Cell and Developmental Biology 11 , 1244425. 10.3389/fcell.2023.1244425 |
Polit, Lucia Dutan, Eidhof, Ilse, McNeill, Rhiannon V., Warre-Cornish, Katherine M., Ohki, Cristine Marie Yde, Walter, Natalie Monet, Sala, Carlo, Verpelli, Chiara, Radtke, Franziska, Galderisi, Silvana, Mucci, Armida, Collo, Ginetta, Edenhofer, Frank, Castrén, Maija L., Réthelyi, János M., Ejlersen, Morten, Hohmann, Sonja Simone, Ilieva, Mirolyuba S., Lukjanska, Renate, Matuleviciute, Rugile, Michel, Tanja Maria, de Vrij, Femke M.S., Kushner, Steven A., Lendemeijer, Bas, Kittel-Schneider, Sarah, Ziegler, Georg C., Gruber-Schoffnegger, Doris, Pasterkamp, R. Jeroen, Kasri, Amal, Potier, Marie-Claude, Knoblich, Jürgen A., Brüstle, Oliver, Peitz, Michael, Pich, Emilio Merlo, Harwood, Adrian J. ORCID: https://orcid.org/0000-0003-3124-5169, Abranches, Elsa, Falk, Anna, Vernon, Anthony C., Grünblatt, Edna and Srivastava, Deepak P. 2023. Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders. Neuroscience Applied 2 , 101125. 10.1016/j.nsa.2023.101125 |
Robinson, Jessica, Uzun, Orhan, Ron Loh, Ne, Harris, Isabelle Rose, Woolley, Thomas E. ORCID: https://orcid.org/0000-0001-6225-5365, Harwood, Adrian ORCID: https://orcid.org/0000-0003-3124-5169, Gardner, Jennifer Frances and Syed, Yasir Ahmed ORCID: https://orcid.org/0000-0001-9495-307X 2022. The association of neurodevelopmental abnormalities, congenital heart and renal defects in a Tuberous Sclerosis Complex patient cohort. BMC Medicine 20 , 123. 10.1186/s12916-022-02325-0 |
Stewart, Balint, Gruenheit, Nicole, Baldwin, Amy ORCID: https://orcid.org/0000-0002-2162-3771, Chisholm, Rex, Rozen, Daniel, Harwood, Adrian ORCID: https://orcid.org/0000-0003-3124-5169, Wolf, Jason B. and Thompson, Christopher R. L. 2022. The genetic architecture underlying prey-dependent performance in a microbial predator. Nature Communications 13 (1) , 319. 10.1038/s41467-021-27844-x |
Gruenheit, Nicole, Baldwin, Amy ORCID: https://orcid.org/0000-0002-2162-3771, Stewart, Balint, Jaques, Sarah, Keller, Thomas, Parkinson, Katie, Salvidge, William, Baines, Robert, Brimson, Chris, Wolf, Jason B., Chisholm, Rex, Harwood, Adrian J. ORCID: https://orcid.org/0000-0003-3124-5169 and Thompson, Christopher R. L. 2021. Mutant resources for functional genomics in Dictyostelium discoideum using REMI-seq technology. BMC Biology 19 (1) , 172. 10.1186/s12915-021-01108-y |
Oliva-Teles, Natália, de Stefano, Maria Chiara, Gallagher, Louise, Rakic, Severin, Jorge, Paula, Cuturilo, Goran, Markovska-Simoska, Silvana, Borg, Isabella, Wolstencroft, Jeanne, Tümer, Zeynep, Harwood, Adrian J. ORCID: https://orcid.org/0000-0003-3124-5169, Kodra, Yllka and Skuse, David 2020. Rare pathogenic copy number variation in the 16p11.2 (BP4–BP5) region associated with neurodevelopmental and neuropsychiatric disorders: a review of the literature. International Journal of Environmental Research and Public Health 17 (24) , 9253. 10.3390/ijerph17249253 |
Davis, Brittany, David, Francois, O’Regan, Ciara, Adam, Manal, Harwood, Adrian ORCID: https://orcid.org/0000-0003-3124-5169, Crunelli, Vincenzo ORCID: https://orcid.org/0000-0001-7154-9752 and Isles, Anthony ORCID: https://orcid.org/0000-0002-7587-5712 2020. Impairments in sensory-motor gating and information processing in a mouse model of Ehmt1 haploinsufficiency. Brain and Neuroscience Advances 4 10.1177/2398212820928647 |
Drakulic, Danijela, Djurovic, Srdjan, Syed, Yasir Ahmed ORCID: https://orcid.org/0000-0001-9495-307X, Trattaro, Sebastiano, Caporale, Nicolò, Falk, Anna, Ofir, Rivka, Heine, Vivi M., Chawner, Samuel J. R. A., Rodriguez-Moreno, Antonio, van den Bree, Marianne B. M. ORCID: https://orcid.org/0000-0002-4426-3254, Testa, Giuseppe, Petrakis, Spyros and Harwood, Adrian J. ORCID: https://orcid.org/0000-0003-3124-5169 2020. Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD. Molecular Autism 11 (1) , 42. 10.1186/s13229-020-00343-4 |
Perry, Christopher J., Finch, Paul, Müller-Taubenberger, Annette, Leung, Kit-Yi, Warren, Eleanor C., Damstra-Oddy, Joseph, Sharma, Devdutt, Patra, Pabitra H., Glyn, Sarah, Boberska, Joanna, Stewart, Balint, Baldwin, Amy ORCID: https://orcid.org/0000-0002-2162-3771, Piscitelli, Fabiana, Harvey, Robert J., Harwood, Adrian ORCID: https://orcid.org/0000-0003-3124-5169, Thompson, Christopher, Claus, Sandrine P., Greene, Nicholas D. E., McNeish, Alister J., Williams, Claire M., Whalley, Benjamin J. and Williams, Robin S. B. 2020. A new mechanism for cannabidiol in regulating the one-carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models. British Journal of Pharmacology 177 (4) , pp. 912-928. 10.1111/bph.14892 |
Plumbly, William, Brandon, Nick, Deeb, Tarek Z., Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Harwood, Adrian J. ORCID: https://orcid.org/0000-0003-3124-5169 2019. L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks. Scientific Reports 9 , 13810. 10.1038/s41598-019-50226-9 |
Nadadhur, Aishwarya G., Alsaqati, Mouhamed, Gasparotto, Lisa, Cornelissen-Steijger, Paulien, van Hugte, Eline, Dooves, Stephanie, Harwood, Adrian J. ORCID: https://orcid.org/0000-0003-3124-5169 and Heine, Vivi M. 2019. Neuron-glia interactions increase neuronal phenotypes in tuberous sclerosis complex patient iPSC-derived models. Stem Cell Reports 12 (1) , pp. 42-56. 10.1016/j.stemcr.2018.11.019 |
Harwood, Adrian ORCID: https://orcid.org/0000-0003-3124-5169 and Baldwin, Amy ORCID: https://orcid.org/0000-0002-2162-3771 2018. Dictyostelium. Encyclopedia of Microbiology (Fourth Edition), Elsevier, pp. 18-27. (10.1016/B978-0-12-809633-8.13033-X) |
Cocorocchio, Marco, Baldwin, Amy ORCID: https://orcid.org/0000-0002-2162-3771, Stewart, Balint, Kim, Lou, Harwood, Adrian ORCID: https://orcid.org/0000-0003-3124-5169, Thompson, Christopher R. L., Andrews, Paul L. R. and Williams, Robin S. B. 2018. Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum. Disease Models & Mechanisms 11 , 032375. 10.1242/dmm.032375 |
Platt, James L., Kent, Nicholas A. ORCID: https://orcid.org/0000-0002-4114-1307, Kimmel, Alan R. and Harwood, Adrian J. ORCID: https://orcid.org/0000-0003-3124-5169 2017. Regulation of nucleosome positioning by a CHD Type III chromatin remodeler and its relationship to developmental gene expression in Dictyostelium. Genome Research 27 , pp. 591-600. 10.1101/gr.216309.116 |
Falk, A, Heine, V M, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Sullivan, P F, Peitz, M, Brüstle, O, Shen, S, Sun, Y-M, Glover, J C, Posthuma, D and Djurovic, S 2016. Modeling psychiatric disorders: from genomic findings to cellular phenotypes. Molecular Psychiatry 21 (9) , pp. 1167-1179. 10.1038/mp.2016.89 |
Tarrés, Màrius, Canetta, Elisabetta, Paul, Eleanor, Forbes, Jordan, Azzouni, Karima, Viñas, Clara, Teixidor, Francesc and Harwood, Adrian J. ORCID: https://orcid.org/0000-0003-3124-5169 2015. Biological interaction of living cells with COSAN-based synthetic vesicles. Scientific Reports 5 , 7804. 10.1038/srep07804 |
Tarrés, Màrius, Canetta, Elisabetta, Viñas, Clara, Teixidor, Francesc and Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 2014. Imaging in living cells using νB–H Raman spectroscopy: monitoring COSAN uptake. Chemical Communications 50 (25) , pp. 3370-3372. 10.1039/c3cc49658a |
Platt, James Louis, Rogers, Benjamin James, Rogers, Kelley C., Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 and Kimmel, Alan R. 2013. Different CHD chromatin remodelers are required for expression of distinct gene sets and specific stages during development of Dictyostelium discoideum. Development 140 (24) , pp. 4926-4936. 10.1242/dev.099879 |
Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Forde -Thomas, Josephine, Williams, Hazel, Samereier, Matthias and Müller-Taubenberger, Annette 2013. Aberrant spindle dynamics and cytokinesis in Dictyostelium discoideum cells that lack glycogen synthase kinase 3. European Journal of Cell Biology 92 (6-7) , pp. 222-228. 10.1016/j.ejcb.2013.05.001 |
Fox, Michael A., Kreis, Patricia, Hendricusdottir, Rita, Kay, Louise, Papageorgiou, Ismini E., van Diepen, Michiel, Mack, Till, Ryves, Jonny, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Leslie, Nicholas R., Kann, Oliver, Parsons, Maddy and Eickholt, Britta J. 2013. Phosphorylation of the Actin Binding Protein Drebrin at S647 Is Regulated by Neuronal Activity and PTEN. PLoS ONE 8 (8) , e71957. 10.1371/journal.pone.0071957 |
Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 2011. Prolyl oligopeptidase, inositol phosphate signalling and lithium sensitivity. CNS & Neurological Disorders - Drug Targets 10 (3) , pp. 333-339. 10.2174/187152711794653779 |
Perrins, Richard D., Orchard, Craig B., Zavodszky, Maria, Kasry, Amal, Nikolaev, Nikolay, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314 and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2011. Doing more with less: a method for low total mass, affinity measurement using variable-length nanotethers. Analytical Chemistry 83 (23) , pp. 8900-8905. 10.1021/ac2012569 |
Teo, Regina Mei Mei, Lewis, Kimberley, Forde, Josephine E., Ryves, William Jonathan, Reddy, Jonathan Venkat, Rogers, Benjamin James and Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 2010. Glycogen synthase kinase-3 is required for efficient 'Dictyostelium' chemotaxis. Molecular Biology of the Cell 21 (15) , pp. 2788-2796. 10.1091/mbc.E09-10-0891 |
King, Jason, Keim, Melanie, Teo, Regina, Weening, Karin Esther, Kapur, Mridu, McQuillan, Karina, Ryves, William Jonathan, Rogers, Benjamin James, Dalton, Emma Charlotte ORCID: https://orcid.org/0000-0002-3517-0742, Williams, Robin S. B. and Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 2010. Genetic control of lithium sensitivity and regulation of inositol biosynthetic genes. PLoS ONE 5 (6) , e11151. 10.1371/journal.pone.0011151 |
Rey, Sara M., Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Povazay, Boris, Hofer, Bernd, Unterhuber, Angelika ORCID: https://orcid.org/0000-0002-1251-3001 and Drexler, Wolfgang 2010. Mutant and wild type cell chemotaxis in 3D and 4D with ultrahigh- resolution optical coherence tomography. Presented at: Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV, San Francisco, CA, USA, 25-27 January 2010. Published in: Izatt, Joseph A., Fujimoto, James G. and Tuchin, Valery V. eds. Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV. Proceedings of SPIE (7554) Bellingham, WA: SPIE, pp. 505-509. 10.1117/12.843244 |
Kasry, Amal, Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314, Davies, Philip Rosser ORCID: https://orcid.org/0000-0003-4394-766X, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Thomas, Nick, Lofas, Stefan and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2009. Comparison of methods for generating planar DNA-modified surfaces for hybridization studies. ACS Applied Materials & Interfaces 1 (8) , pp. 1793-1798. 10.1021/am9003073 |
Rey, Sara Maria, Považay, Boris, Hofer, Bernd, Unterhuber, A., Hermann, Boris ORCID: https://orcid.org/0000-0001-8658-485X, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 and Drexler, Wolfgang 2009. Three- and four-dimensional visualization of cell migration using optical coherence tomography. Journal of Biophotonics 2 (6-7) , pp. 370-379. 10.1002/jbio.200910027 |
Rey, Sara Maria, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Povazay, Boris, Hofer, Bernd, Unterhuber, Angelika ORCID: https://orcid.org/0000-0002-1251-3001, Hermann, Boris ORCID: https://orcid.org/0000-0001-8658-485X and Drexler, Wolfgang 2009. Visualization of 3D cell migration using high speed ultrahigh resolution optical coherence tomography. Presented at: Optics in tissue engineering and regenerative medicine III, San Jose, CA, USA, 24 January 2009. Published in: Kirkpatrick, Sean J. and Wang, Ruikang eds. Optics in Tissue Engineering and Regenerative Medicine III, 24 January 2009, San Jose, CA, USA. Proceedings of SPIE (7179) Bellingham, WA: SPIE - International Society for Optical Engineering, pp. 505-509. 10.1117/12.809178 |
Shimshoni, J. A., Dalton, Emma Charlotte ORCID: https://orcid.org/0000-0002-3517-0742, Watson, Peter Duncan ORCID: https://orcid.org/0000-0003-0250-7852, Yagen, B., Bialer, M. and Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 2009. Evaluation of the effects of propylisopropylacetic acid (PIA) on neuronal growth cone morphology. Neuropharmacology 56 (4) , pp. 831-837. 10.1016/j.neuropharm.2009.01.014 |
King, Jason, Teo, Regina, Ryves, William Jonathan, Reddy, Jonathan Venkat, Peters, Owen Morgan ORCID: https://orcid.org/0000-0002-6824-0663, Orabi, Ben, Hoeller, Oliver, Williams, Robin S. B. and Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 2009. The mood stabiliser lithium suppresses PIP3 signalling in 'Dictyostelium' and human cells. Disease Models & Mechanisms 2 (5-6) , pp. 306-312. 10.1242/dmm.001271 |
Teo, Regina Mei Mei, King, J., Dalton, Emma Charlotte ORCID: https://orcid.org/0000-0002-3517-0742, Ryves, William Jonathan, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 and Williams, R. S. B. 2009. Ptdins (3,4,5)P-3 and inositol depletion as a cellular target of mood stabilizers. Biochemical Society Transactions 37 (5) , pp. 1110-1114. 10.1042/BST0371110 |
Peineau, Stéphane, Nicolas, Céline, Bortolotto, Zuner, Bhat, Ratan, Ryves, William Jonathan, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Dournaud, Pascal, Fitzjohn, Stephen and Collingridge, Graham 2009. A systematic investigation of the protein kinases involved in NMDA receptor-dependent LTD: evidence for a role of GSK-3 but not other serine/threonine kinases. Molecular Brain 2 (1) , 22. 10.1186/1756-6606-2-22 |
Cho, Jalesoon, King, Jason, Qian, Xun, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 and Shears, Stephen B. 2008. Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt. Proceedings of the National Academy of Sciences of the United States of America 105 (16) , pp. 5998-6003. 10.1073/pnas.0710980105 |
Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 2008. Dictyostelium development: a prototypic Wnt pathway? Vincan, E., ed. Wnt Signaling, Vol. 2. Methods in Molecular Biology, vol. 469. New York, NY: Humana Press, pp. 21-32. (10.1007/978-1-60327-469-2_2) |
Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 2008. Monitoring patterns of gene expression in Dictyostelium by beta-galacotsidase staining. Vincan, E., ed. Wnt signaling- Pathway models, Vol. 2. Methods in Molecular Biology, vol. 469. Totowa, N.J.: Humana, pp. 33-37. |
Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 2008. Use of the Dictyostelium stalk cell assay to monitor GSK-3 regulation. Vincan, Elizabeth, ed. Wnt Signaling, Vol. 469. Methods in Molecular Biology, Springer, pp. 39-43. (10.1007/978-1-60327-469-2_4) |
University College Cardiff Consultants, Ltd. 2008. Method of measuring the affinity of biomolecules. EP1949104A2. [Patent]. |
Shaltiel, Galit, Dalton, Emma Charlotte ORCID: https://orcid.org/0000-0002-3517-0742, Belmaker, Robert H., Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 and Agam, Galila 2007. Specificity of mood stabilizer action on neuronal growth cones. Bipolar Disorders 9 (3) , pp. 281-289. 10.1111/j.1399-5618.2007.00400.x |
Strmecki, L., Bloomfield, G., Araki, T., Dalton, Emma Charlotte ORCID: https://orcid.org/0000-0002-3517-0742, Skelton, J., Schilde, C., Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Williams, J. G., Ivens, A. and Pears, C. 2007. Proteomic and microarray analyses of the Dictyostelium Zak1-GSK-3 signaling pathway reveal a role in early development. Eukaryotic Cell 6 (2) , pp. 245-252. 10.1128/EC.00204-06 |
Shimshoni, J. A., Dalton, Emma Charlotte ORCID: https://orcid.org/0000-0002-3517-0742, Jenkins, A., Eyal, S., Ewan, Kenneth Burnside Ramsay ORCID: https://orcid.org/0000-0001-6622-9009, Williams, R. S. B., Pessah, N., Yagen, B., Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 and Bialer, M. 2006. The effects of central nervous system-active valproic acid constitutional isomers, cyclopropyl analogs, and amide derivatives on neuronal growth cone behavior. Molecular Pharmacology 71 (3) , pp. 884-892. 10.1124/mol.106.030601 |
Ryves, William Jonathan, Dalton, Emma Charlotte ORCID: https://orcid.org/0000-0002-3517-0742, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 and Williams, Robin S. B. 2005. GSK-3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid. Bipolar Disorders , pp. 260-265. 10.1111/j.1399-5618.2005.00194.x |
Schilde, Christina, Araki, Tsuyoshi, Williams, Hazel, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 and Williams, Jeffrey G. 2004. GSK-3 is a multi-functional regulator of Dictyostelium development. Development 131 (18) , pp. 4555-4565. 10.1242/dev.01330 |
Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Kim, L. and Kimmel, A.R. 2002. Receptor-dependent and tyrosine phosphatase-mediated inhibition of GSK3 regulates cell fate choice. Developmental Cell , pp. 523-532. 10.1016/S1534-5807(02)00269-1 |
Williams, Robin S. B., Cheng, Lili, Mudge, Anne W. and Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 2002. A common mechanism of action for three mood-stabilizing drugs. Nature 417 (6886) , pp. 292-295. 10.1038/417292a |
Fraser, Elizabeth, Young, N., Dajani, R., Franca-Koh, J., Ryves, William Jonathan, Williams, R. S. B., Yeo, M., Webster, M.-T., Richardson, C., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Pearl, L. H., Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2002. Identification of the Axin and Frat binding region of glycogen synthase kinase-3. Journal of Biological Chemistry 277 (3) , pp. 2176-2185. 10.1074/jbc.M109462200 |