Qin, Marong, Mishra, Pawan ORCID: https://orcid.org/0000-0003-1141-3487, Hind, Jasmine, Fallis, Ian ORCID: https://orcid.org/0000-0001-7361-0182 and Tredwell, Matthew ORCID: https://orcid.org/0000-0002-4184-5611
2025.
The synthesis of [18F]SynVesT-1 and [18F]SynVesT-2 from enantioenriched boronic esters.
Chemical Communications
10.1039/D5CC05507E
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Official URL: http://dx.doi.org/10.1039/D5CC05507E
Abstract
Enantioenrcihed [18F]SynVesT-1 and [18F]SynVesT-2 are prepared from the corresponding enantioenriched arylboronic esters and [18F]fluoride mediated by (Py)4Cu(OTf)2. The 18F-reaction is optimised on an automated synthesiser to produce multi-GBq quantites of both radiotracers to support (pre)clinical imaging.
| Item Type: | Article |
|---|---|
| Date Type: | Published Online |
| Status: | In Press |
| Schools: | Schools > Chemistry |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1359-7345 |
| Date of First Compliant Deposit: | 14 October 2025 |
| Date of Acceptance: | 8 October 2025 |
| Last Modified: | 07 Nov 2025 22:19 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/181605 |
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