Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

Naghavi, Mohsen, Kyu, Hmwe, Bhoomadevi, A., Aalipour, Mohammad Amin, Aalruz, Hasan, Ababneh, Hazim S., Abafita, Bedru J., Abarogu, Ukachukwu O., Abbafati, Cristina, Abbasi, Mardineh, Abbaspour, Faezeh, Abbastabar, Hedayat, Abd Al Magied, Abdallah H. A., Abd ElHafeez, Samar, Abdalla, Ashraf Nabiel, Abdalla, Mohammed Altigani, Abdalla, Emad M., Abdeeq, Barkhad Aden, GBD 2023 Causes of Death Collaborators and Sha'aban, A. ORCID: https://orcid.org/0000-0002-5491-9851 2025. Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023. The Lancet 406 (10513) , pp. 1811-1872. 10.1016/S0140-6736(25)01917-8

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Abstract

Background Timely and comprehensive analyses of causes of death stratified by age, sex, and location are essential for shaping effective health policies aimed at reducing global mortality. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023 provides cause-specific mortality estimates measured in counts, rates, and years of life lost (YLLs). GBD 2023 aimed to enhance our understanding of the relationship between age and cause of death by quantifying the probability of dying before age 70 years (70q0) and the mean age at death by cause and sex. This study enables comparisons of the impact of causes of death over time, offering a deeper understanding of how these causes affect global populations.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine
Additional Information:	For the full list of authors, please refer to the article webpage at https://doi.org/10.1016/S0140-6736(25)01917-8
Publisher:	Elsevier
ISSN:	0140-6736
Date of First Compliant Deposit:	21 October 2025
Last Modified:	22 Oct 2025 09:00
URI:	https://orca.cardiff.ac.uk/id/eprint/181813

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