Ensembl 2026

Yates, Andrew D, Austine-Orimoloye, Olanrewaju, Azov, Andrey G, Barba, Matthieu, Barnes, If, Barrera-Enriquez, Vianey Paola, Becker, Arne, Bennett, Ruth, Berry, Andrew, Bhai, Jyothish, Bhurji, Simarpreet Kaur, Branco Lins, Paulo R., Brooks, Lucy, Budhanuru Ramaraju, Shashank, Campbell, Lahcen I., Carbajo Martinez, Manuel, Carpenter, Jack, Charkhchi, Mehrnaz, Cortes, Lucas A., Davidson, Claire, Dickson, Suzanna, Dodiya, Kamalkumar, Donaldson, Sarah, El Houdaigui, Bilal, El Naboulsi, Tamara, Fairbrother-Browne, Aine, Falola, Oluwadamilare, Fatima, Reham, Gonzalez Martinez, Jose, Gurbich, Tatiana, Hall, Holly, Hardy, Matthew, Hollis, Zoe, Hunt, Toby, Kay, Mike, Kaikala, Vinay, Lazar, Anna, Lemos, Diana, Lodha, Disha, Mathlouthi, Nourhen, Merino, Gabriela A., Merritt, Ryan, Mirabueno, Louisse Paola, Mushtaq, Aleena, Nakib Hossain, Syed, Pérez-Silva, José G., Piližota, Ivana, Poppleton, Daniel, Prosovetskaia, Irina, Raj, Shriya, Salam, Ahamed Imran Abdul, Saraf, Shradha, Sinha, Swati, Sipos, Botond, Sitnik, Vasily, Suner, Marie-Marthe, Surapaneni, Likhitha, Tierney, Jack A .S., Urbina-Gómez, David, Veidenberg, Andres, Walsh, Thomas A., Allen, Jamie M., Alvarez-Jarreta, Jorge, Cheema, Jitender, Batista da Rocha, Jorge, De Silva, Nishadi H., Tricomi, Francesca Floriana, Giorgetti, Stefano, Ilsley, Garth R., Keatley, Jon, Loveland, Jane E., Mudge, Jonathan M., Naamati, Guy, Tate, John, Willhoft, Natalie L., Winterbottom, Andrea, Flint, Bethany R., Frankish, Adam, Haggerty, Leanne, Hunt, Sarah E., Clark, Emily L., Dyer, Sarah C., Freeberg, Mallory A., Martin, Fergal J. and Finn, Robert D. 2025. Ensembl 2026. Nucleic Acids Research , gkaf1239. 10.1093/nar/gkaf1239

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Abstract

The Ensembl project (https://www.ensembl.org) is a public and open resource providing access to genomes, annotations, high-quality tools, and methods applicable to species from across the tree of life. This year has witnessed nearly a doubling in our rate of annotation and genome release, with 1927 new genomes released, with the total number of genomes now standing at 37 546. This includes expanded support for the human and barley pangenomes. We also present two new interfaces providing improved mechanisms to explore and interrogate genome regulation annotations. As our focus remains on sustainable scaling, we have archived Ensembl Rapid Release and accelerated the move to the new Ensembl platform. Ensembl release 116 (Q1-2026) will be the last release on the current platform.

Item Type:	Article
Date Type:	Published Online
Status:	In Press
Schools:	Schools > Biosciences
Additional Information:	License information from Publisher: LICENSE 1: URL: https://creativecommons.org/licenses/by/4.0/, Type: cc-by
Publisher:	Oxford University Press
ISSN:	0305-1048
Date of First Compliant Deposit:	2 December 2025
Date of Acceptance:	16 October 2025
Last Modified:	02 Dec 2025 12:30
URI:	https://orca.cardiff.ac.uk/id/eprint/182825

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