Petrik, David  ORCID: https://orcid.org/0000-0003-3026-0770
2025.
Neurogenic hypothesis of anti-obesity action: is it on the horizon?
Obesity and Endocrinology
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, wjaf014.
10.1093/obendo/wjaf014
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License URL: https://creativecommons.org/licenses/by/4.0/
License Start date: 25 November 2025
Official URL: https://doi.org/10.1093/obendo/wjaf014
Abstract
This commentary explores the emerging connection between hypothalamic adult neurogenesis (hAN), obesity, and antiobesity medications (AOMs). It highlights recent findings suggesting that AOMs influence hAN and may act, at least in part, through neurogenic mechanisms. This commentary debates a neurogenic hypothesis of obesity and its treatment, offering a conceptual framework that could open new therapeutic avenues and enhance our understanding of energy homeostasis regulation.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Biosciences |
| Additional Information: | License information from Publisher: LICENSE 1: URL: https://creativecommons.org/licenses/by/4.0/, Start Date: 2025-11-25 |
| Publisher: | Oxford University Press (OUP) |
| Date of First Compliant Deposit: | 9 December 2025 |
| Date of Acceptance: | 20 November 2025 |
| Last Modified: | 15 Jan 2026 11:19 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/183031 |
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