EndoCompass project: Research roadmap for thyroid endocrinology.

Piekielko-Witkowska, Agnieszka, Elisei, Rossella, Léger, Juliane, Bendlova, Bela, Bulanová Pekova, Barbora, Caron, Philippe, Durante, Cosimo, Fassnacht, Martin, Feldt-Rasmussen, Ulla, Filipsson Nyström, Helena, Jansen, Heleen, Köhrle, Josef, Kus, Aleksander, Ludgate, Marian, Mertens, Jonathan, Oczko-Wojciechowska, Małgorzata, Peters, Catherine, Schoenmakers, Nadia, Stoupa, Athanasia, van Santen, Hanneke, Trimboli, Pierpaolo, van Trotsenburg, Paul and Visser, W Edward 2025. EndoCompass project: Research roadmap for thyroid endocrinology. Hormone Research in Paediatrics 98 (Suppl.) , pp. 144-157. 10.1159/000549075

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Abstract

Endocrine science remains underrepresented in European Union research programs despite the fundamental role of hormone health in human well-being. Analysis of the CORDIS database reveals a persistent gap between the societal impact of endocrine disorders and their research prioritization. At national funding level, endocrine societies report limited or little attention of national research funding toward endocrinology. The EndoCompass project - a joint initiative between the European Society of Endocrinology and the European Society of Paediatric Endocrinology, aimed to identify and promote strategic research priorities in endocrine science to address critical hormone-related health challenges. Research priorities were established through comprehensive analysis of the EU CORDIS database covering the Horizon 2020 framework period (2014-2020). Expert consultation in thyroid endocrinology was conducted to identify key research priorities, followed by broader stakeholder engagement including society members and patient advocacy groups. For thyroid disorders, research priorities encompass neoplastic and nonneoplastic conditions, focusing on disease mechanisms, improved diagnostics and treatments, and the impact of environmental and metabolic factors. Key areas include personalized medicine approaches, artificial intelligence applications, and the establishment of pan-European registries to advance understanding of rare thyroid conditions. The thyroid component of the EndoCompass project provides an evidence-based roadmap for strategic research investment. This framework identifies crucial investigation areas into thyroid disease pathophysiology, prevention, and treatment strategies, ultimately aimed at reducing the burden of thyroid disorders on individuals and society. The findings support the broader EndoCompass objective of aligning research funding with areas of highest potential impact in endocrine health. [Abstract copyright: © 2025 The Author(s). Published by S. Karger AG, Basel.]

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine
Publisher:	Karger Publishers
ISSN:	1663-2818
Date of First Compliant Deposit:	18 December 2025
Date of Acceptance:	14 October 2025
Last Modified:	18 Dec 2025 12:30
URI:	https://orca.cardiff.ac.uk/id/eprint/183371

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