Adaptive versus fixed designs in confirmatory clinical trials: centering the choice on ethics

Baas, Stef, Pin, Lukas, Robertson, David S, Bretz, Frank, Cho, Hearn Jay, Flight, Laura, van der Graaf, Rieke, Graham, Mackenzie, Jacko, Peter, Jaki, Thomas, Kimmelman, Jonathan, Manfrin, Andrea, Milne, Richard, Mozgunov, Pavel, Pallmann, Philip ORCID: https://orcid.org/0000-0001-8274-9696, Parke, Tom, Parmar, Mahesh K B, Pirard, Vincaine, Sahan, Kate, Singh, Jerome, Tom, Brian D M, Whittaker, John C, Wozniak, Kate, Wright, David, Zheng, Haiyan, London, Alex John, Sheehan, Mark and Villar, Sofia 2025. Adaptive versus fixed designs in confirmatory clinical trials: centering the choice on ethics. SSRN , 5937835.

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Item Type:	Article
Date Type:	Published Online
Status:	Submitted
Schools:	Research Institutes & Centres > Centre for Trials Research (CNTRR)
Related URLs:	Publisher
Last Modified:	23 Dec 2025 16:15
URI:	https://orca.cardiff.ac.uk/id/eprint/183429

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