Steps on the path to clinical translation—a British and Irish chapter ISMRM workshop survey of the UK MRI community

Markus, Julia E., Hubbard Cristinacce, Penny L., Punwani, Shonit, O'Connor, James P. B., Mills, Rebecca, Yanez Lopez, Maria, Grech‐Sollars, Matthew, Fasano, Fabrizio, Waterton, John C., Thrippleton, Michael J., Hall, Matt G., Francis, Susan T., Statton, Ben, Murphy, Kevin ORCID: https://orcid.org/0000-0002-6516-313X, So, Po‐Wah and Hyare, Harpreet 2025. Steps on the path to clinical translation—a British and Irish chapter ISMRM workshop survey of the UK MRI community. Magnetic Resonance in Medicine , mrm.70225. 10.1002/mrm.70225

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Abstract

Our goal was to understand the barriers and challenges to clinical translation of quantitative MR (qMR) as perceived by stakeholders in the UK. We conducted an electronic survey on seven key areas related to clinical translation of qMR, developed at the BIC‐ISMRM workshop: “Steps on the path to clinical translation”. Based on the seven areas identified: (i) clinical workflow, (ii) changes in clinical practice, (iii) improving validation, (iv) standardization of data acquisition and analysis, (v) sharing of data and code, (vi) improving quality management, and (vii) end‐user engagement, a 40‐question survey was developed. Members of BIC‐ISMRM, MR‐PHYSICS, BSNR and institutional mailing lists were invited to respond to the online survey over a 5‐week period between September and October 2022. The responses were analysed via descriptive statistics of multiple‐choice questions, Likert scores and a thematic analysis of free text questions. A total of 69 responses were received from predominantly research imaging scientists (69%) in numerous centres across the UK. Three main themes were identified: (1) Consensus; the need to develop in terminology, decision making and validation; (2) Context Dependency; an appreciation of the uniqueness of each clinical situation, and (3) Product Profile; a clear description of the imaging biomarker and its intended use. Effective translation of qMR imaging and spectroscopic biomarkers to achieve their full clinical potential must address the differing needs and expectations of a wide range of stakeholders.

Item Type:	Article
Date Type:	Published Online
Status:	In Press
Schools:	Schools > Physics and Astronomy Research Institutes & Centres > Cardiff University Brain Research Imaging Centre (CUBRIC)
Additional Information:	License information from Publisher: LICENSE 1: URL: http://creativecommons.org/licenses/by/4.0/, Start Date: 2025-12-19
Publisher:	Wiley
ISSN:	0740-3194
Date of First Compliant Deposit:	7 January 2026
Date of Acceptance:	21 November 2025
Last Modified:	07 Jan 2026 15:00
URI:	https://orca.cardiff.ac.uk/id/eprint/183686

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