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Evaluating progesterone receptor agonist megestrol plus letrozole for women with early-stage estrogen-receptor-positive breast cancer: the window-of-opportunity, randomized, phase 2b, PIONEER trial

Burrell, Rebecca A., Kumar, Sanjeev, Provenzano, Elena, Pike, Cleopatra, Dayimu, Alimu, McIntosh, Stuart A., Pitsinis, Vassilis, King, Polly, Elsberger, Beatrix, Govindarajulu, Sasi, Satherley, Lucy, Hadad, Sirwan, Schmid, Peter, Agrawal, Amit, Akpuluma, Bodiere, Bell, Steven, Benson, John R., Caldas, Carlos, Cheeseman, Danya, Chernukhin, Igor, Forouhi, Parto, Gulsen, Tulay, Kleidi, Eleftheria, Pinilla, Karen, Qian, Wendi, Abraham, Jean E., Carroll, Jason S. and Baird, Richard D. 2026. Evaluating progesterone receptor agonist megestrol plus letrozole for women with early-stage estrogen-receptor-positive breast cancer: the window-of-opportunity, randomized, phase 2b, PIONEER trial. Nature Cancer 10.1038/s43018-025-01087-x

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Item Type: Article
Date Type: Publication
Status: In Press
Schools: Schools > Medicine
Publisher: Nature Research
ISSN: 2662-1347
Date of First Compliant Deposit: 12 January 2026
Last Modified: 12 Jan 2026 16:15
URI: https://orca.cardiff.ac.uk/id/eprint/183815

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