The association between academic pressure and adolescent depressive symptoms and self-harm: a longitudinal, prospective study in England

Guo, Xuchen, Mueller, Marie A. E., Armitage, Jessica M., Bonell, Chris, Ford, Tamsin J., John, Ann, Lewis, Glyn, Murphy, Simon ORCID: https://orcid.org/0000-0003-3589-3681, Ploubidis, George, Rice, Frances ORCID: https://orcid.org/0000-0002-9484-1729, Sullivan, Alice and Lewis, Gemma 2026. The association between academic pressure and adolescent depressive symptoms and self-harm: a longitudinal, prospective study in England. The Lancet Child & Adolescent Health 10.1016/s2352-4642(25)00342-6

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Abstract

Background: Academic pressure could increase the risk of adolescent depression and self-harm. However, there are few longitudinal studies of this association, and those that exist have limitations. We aimed to investigate associations between perceived levels of academic pressure and subsequent depressive symptoms and self-harm from adolescence to early adulthood. Our hypothesis was that higher levels of academic pressure would be associated with higher levels of depressive symptoms and self-harm. Methods: In this longitudinal study, we used data from the Avon Longitudinal Study of Parents and Children (Avon, UK) that includes adolescents born in 1991–92. Our primary exposure of interest was academic pressure measured at age 15 years, using items from a school experiences questionnaire (total scores 0–9). Outcomes were depressive symptoms assessed with the Short Mood and Feelings Questionnaire at five timepoints between age 16 years and 22 years (total scores 0–26), and a self-harm questionnaire at four timepoints between age 16 years and 24 years. Analyses were linear (depressive symptoms) and logistic (self-harm in the previous year) multilevel models in samples with multiply imputed data, before and after adjustments. Findings: We included 4714 adolescents (2725 [57·8%] female, 1989 [42·2%] male). In fully adjusted models, a 1-point increase in academic pressure at age 15 years was associated with a 0·43 (95% CI 0·36–0·51) point increase in depressive symptoms. This association was largest when depressive symptoms were assessed at age 16 years (0·53, 0·42–0·64), but remained at age 22 years (0·35, 0·23–0·47). For self-harm, in fully adjusted models, each 1-point increase in academic pressure was associated with an 8% higher odds of self-harm (adjusted odds ratio 1·08, 1·01–1·16), with no differences over time. Interpretation: Our findings support the hypothesis that academic pressure is a potential modifiable risk factor for adolescent depressive symptoms, and possibly self-harm. Interventions to reduce academic pressure could be developed and evaluated.

Item Type:	Article
Date Type:	Published Online
Status:	In Press
Schools:	Schools > Social Sciences (Includes Criminology and Education) Schools > Medicine Research Institutes & Centres > Centre For Development and Evaluation of Complex Interventions for Public Health Improvement (DECIPHer)
Publisher:	Elsevier BV
ISSN:	2352-4642
Date of First Compliant Deposit:	23 February 2026
Date of Acceptance:	13 November 2025
Last Modified:	23 Feb 2026 14:41
URI:	https://orca.cardiff.ac.uk/id/eprint/185112

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