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Nepetalactol oxidoreductase in trichomes of the catmint Nepeta racemosa

Hallahan, David L., West, Jevon M., Smiley, Diane W. M. and Pickett, John A. ORCID: https://orcid.org/0000-0002-8386-3770 1998. Nepetalactol oxidoreductase in trichomes of the catmint Nepeta racemosa. Phytochemistry 48 (3) , pp. 421-427. 10.1016/S0031-9422(98)00006-5

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Abstract

Isomers of (7S)-nepetalactone are the principal constituents of the essential oil accumulated by plants of the genus Nepeta (catmints), with the cis,cis-isomer predominating in the catmint N. racemosa. An enzyme which catalyses the NAD+-dependent oxidation of cis,cis-nepetalactol to cis,cis-nepetalactone has been identified in cell-free extracts of N. racemosa leaves. This enzyme has been partially purified and has been shown to be located within trichomes present on the surface of leaves of this species. Because glandular trichomes have been shown to be the site of accumulation of nepetalactones in N. racemosa and N. cataria, the presence of such activity within the trichomes suggests that nepetalactol may be an intermediate in the biosynthesis of nepetalactone.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Schools > Chemistry
Publisher: Elsevier
ISSN: 0031-9422
Last Modified: 24 Feb 2026 16:15
URI: https://orca.cardiff.ac.uk/id/eprint/185195

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