491 - yoda1-mediated piezo1 activation and proinflammatory il-6 induces catabolic signalling in a human STEM cell derived osteochondral model [Abstract]

Gilbert, Sophie, Church, Matthew, Plant, Stanley and Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254 2026. 491 - yoda1-mediated piezo1 activation and proinflammatory il-6 induces catabolic signalling in a human STEM cell derived osteochondral model [Abstract]. Osteoarthritis and Cartilage 34 (S) , S341. 10.1016/j.joca.2026.01.489

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Abstract

Purpose (the aim of the study): To use a chondrocyte-osteocyte co-culture model of the osteochondral interface to gain mechanistic insight into mechano- and inflammatory signaling in early-stage osteoarthritis.

Item Type:	Short Communication
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine Schools > Biosciences
Publisher:	Elsevier
ISSN:	1063-4584
Last Modified:	01 Jun 2026 07:44
URI:	https://orca.cardiff.ac.uk/id/eprint/186754

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