Gilbert, Sophie J., Soul, Jamie, Hao, Yao, Lin, Hua, Piróg, Katarzyna A., Coxhead, Jonathan, Patel, Krutik, Barter, Matt J., Young, David A. and Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254 2024. Comparative transcriptomic analysis of articular cartilage of post-traumatic osteoarthritis mouse models. Disease Models & Mechanisms 17 (10) , dmm050583. 10.1242/dmm.050583 |
Markov, Petar, Zhu, Hanxing ORCID: https://orcid.org/0000-0002-3209-6831, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547 and Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254 2022. Delayed reorganisation of F-actin cytoskeleton and reversible chromatin condensation in scleral fibroblasts under simulated pathological strain. Biochemistry and Biophysics Reports 32 , 101338. |
Gilbert, Sophie Jane, Bonnet, Cleo Selina and Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2021. Mechanical cues: bidirectional reciprocity in the extracellular matrix drives mechano-signalling in articular cartilage. International Journal of Molecular Sciences 22 (24) , 13595. 10.3390/ijms222413595 |
Markov, Petar, Hayes, Anthony J., Zhu, Hanxing ORCID: https://orcid.org/0000-0002-3209-6831, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547 and Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254 2021. 3D immuno-confocal image reconstruction of fibroblast cytoskeleton and nucleus architecture. Journal of Biophotonics 14 (1) , e202000202. 10.1002/jbio.202000202 |
Stadnik, Paulina S., Gilbert, Sophie J., Tarn, Jessica, Charlton, Sarah, Skelton, Andrew J., Barter, Matthew J., Duance, Victor C. ORCID: https://orcid.org/0000-0002-7555-2016, Young, David A. and Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254 2021. Regulation of microRNA‐221, ‐222, ‐21 and ‐27 in articular cartilage subjected to abnormal compressive forces. Journal of Physiology 599 (1) , pp. 143-155. 10.1113/JP279810 |
Lawrence, Elizabeth A., Hammond, Chrissy L. and Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254 2020. Potential of zebrafish as a model to characterise MicroRNA profiles in mechanically mediated joint degeneration. Histochemistry and Cell Biology 154 , pp. 521-531. 10.1007/s00418-020-01918-1 |
Carter, Jorge and Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254 2019. Effects of Superoxide Dismutase 1 on cartilage chondrocyte metabolism: a protective mechanism against ankle osteoarthritis? The British Student Doctor Journal 3 (3) , pp. 35-37. 10.18573/bsdj.125 |
Pijanka, Jacek K., Markov, Petar P., Midgett, Dan, Paterson, Neil G., White, Nick, Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254, Nguyen, Thao D., Quigley, Harry A. and Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547 2019. Quantification of collagen fiber structure using second harmonic generation imaging and two‐dimensional discrete Fourier transform analysis: application to the human optic nerve head. Journal of Biophotonics 12 (5) , e201800376. 10.1002/jbio.201800376 |
Al-Sabah, Ayesha, Burnell, Stephanie E.A., Simoes, Irina N., Jessop, Zita, Badiei, Nafiseh, Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254 and Whitaker, Iain S. 2019. Structural and mechanical characterization of crosslinked and sterilised nanocellulose-based hydrogels for cartilage tissue engineering. Carbohydrate Polymers 212 , pp. 242-251. 10.1016/j.carbpol.2019.02.057 |
Markov, Petar, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Zhu, Hanxing ORCID: https://orcid.org/0000-0002-3209-6831 and Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254 2019. Building a cell-specific cytoskeletal finite element model of scleral fibroblasts. Presented at: 25th Congress of the European Society of Biomechanics (ESB 2019), Vienna, Austria, 7-10 July 2019. -. |
Markov, Petar, Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547, Zhu, Hanxing ORCID: https://orcid.org/0000-0002-3209-6831 and Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254 2019. Effects of mechanical load on cytoskeletal protein arrangement in scleral fibroblasts. Presented at: The Association for Research in Vision and Ophthalmology Annual Meeting, Vancouver, BC, Canada, 28 April -- 2 May 2019. |
Gilbert, Sophie J., Bonnet, Cleo S., Stadnik, Paulina, Duance, Victor C. ORCID: https://orcid.org/0000-0002-7555-2016, Mason, Deborah J. ORCID: https://orcid.org/0000-0002-8666-6094 and Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254 2018. Inflammatory and degenerative phases resulting from anterior cruciate rupture in a non-invasive murine model of post-traumatic osteoarthritis. Journal of Orthopaedic Research 36 (8) , pp. 2118-2127. 10.1002/jor.23872 |
Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254 and Duance, Victor ORCID: https://orcid.org/0000-0002-7555-2016 2018. Meniscus. Hutson, Mike and Speed, Cathy, eds. Sports Injuries, Oxford UK: Oxford University Press, pp. 45-53. |
Gilbert, Sophie and Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254 2018. Cartilage mechanobiology: how chondrocytes respond to mechanical load. Verbruggen, Stefaan, ed. Mechanobiology in Health and Disease, London UK: Elsevier, pp. 99-126. |
Markov, Peter, Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254 and Zhu, Hanxing ORCID: https://orcid.org/0000-0002-3209-6831 2018. Can particle accelerators help prevent blindness? Presented at: The UCL SenSyT (Sensory Systems, Technologies and Therapies) Symposium 2018, UCL, London, 3 December 2018. |
Wilkinson, David J., Desilets, Antoine, Lin, Hua, Charlton, Sarah, del Carmen Arques, Maria, Falconer, Adrian, Bullock, Craig, Hsu, Yu-Chen, Birchall, Kristian, Hawkins, Alastair, Thompson, Paul, Ferrell, William R., Lockhart, John, Plevin, Robin, Zhang, Yadan, Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254, Lin, Shu-Wha, Leduc, Richard, Milner, Jennifer M. and Rowan, Andrew D. 2017. The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover. Scientific Reports 7 , 16693. 10.1038/s41598-017-17028-3 |
Khatib, Nidal, Metcalfe, Andrew, Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254, Mason, D and Holt, Catherine ORCID: https://orcid.org/0000-0002-0428-8078 2016. Developing an in vitro model of healthy and OA medial knee compartmental loading. Osteoarthritis and Cartilage 24 (Supp 1) , S344. 10.1016/j.joca.2016.01.617 |
Al-Sabah, Ayesha, Stadnik, Paulina, Gilbert, Sophie, Duance, Victor ORCID: https://orcid.org/0000-0002-7555-2016 and Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254 2016. Importance of reference gene selection for articular cartilage mechanobiology studies. Osteoarthritis and Cartilage 24 (4) , pp. 719-730. 10.1016/j.joca.2015.11.007 |
Wyatt, Hayley Louise, Richards, Rosie, Pullin, Rhys ORCID: https://orcid.org/0000-0002-2853-6099, Yang, T. H. Jimmy, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 and Evans, Samuel ORCID: https://orcid.org/0000-0003-3664-2569 2016. Variation in electrosurgical vessel seal quality along the length of a porcine carotid artery. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 230 (3) , pp. 169-174. 10.1177/0954411915621092 |
Ali, Ahmed Y., Yeo, Syn, Ellis, Sadie, Ade, Jamilla, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Esa, Adam, Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254, Bowen, Ifor D. and Martin, Tracey A. ORCID: https://orcid.org/0000-0003-2690-4908 2015. Anti-metastatic and cytotoxic properties of frankincense and scented myrrh. Anticancer Research 35 (7) , pp. 4310-4311. |
Gilbert, Sophie Jane, Meakin, L. B., Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2014. The use of a non-invasive murine knee joint loading model to identify mechano-regulated genes in vivo. International Journal of Experimental Pathology 95 (3) , A11-A12. 10.1111/iep.12078 |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Thomas, Rhian Sara and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2012. Effect of Wnt3A on load-induced markers of chondrocyte matrix metabolism. International Journal of Experimental Pathology 93 (4) , A13-A14. 10.1111/j.1365-2613.2012.00822.x |
Gilbert, Sophie Jane, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Al-Sabah, Ayesha, Zhang, Yadan, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2012. Protein kinase R plays a pivotal role in oncostatin M and interleukin-1 signalling in bovine articular cartilage chondrocytes. European Cells and Materials 23 , pp. 41-57. |
Khan, Ilyas Mahmood, Evans, Samuel Lewin ORCID: https://orcid.org/0000-0003-3664-2569, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Avery, Nick and Archer, Charles William 2011. Fibroblast growth factor 2 and transforming growth factor β1 induce precocious maturation of articular cartilage. Arthritis & Rheumatism 63 (11) , pp. 3417-3427. 10.1002/art.30543 |
Wyatt, Hayley Louise, Richards, R., Evans, Samuel Lewin ORCID: https://orcid.org/0000-0003-3664-2569, Pullin, Rhys ORCID: https://orcid.org/0000-0002-2853-6099, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 and Yang, T. 2011. Relationship of tissue composition on arterial tissue adhesion strength. Presented at: 24th European Conference on Biomaterials ESB2011, Dublin, Ireland, 4-9 September 2011. |
Dachtler, James ORCID: https://orcid.org/0000-0001-6942-7844, Hardingham, Neil Robert, Glazewski, Stanislaw, Wright, Nicholas Fraser, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 and Fox, Kevin Dyson ORCID: https://orcid.org/0000-0002-2563-112X 2011. Experience-dependent plasticity acts via GluR1 and a novel neuronal nitric oxide synthase-dependent synaptic mechanism in adult cortex. Journal of Neuroscience 31 (31) , pp. 11220-11230. 10.1523/JNEUROSCI.1590-11.2011 |
Li, Siyuan, Jia, X., Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2011. The effects of cyclic tensile strain on the organisation and expression of cytoskeletal elements in bovine intervertebral disc cells: an in vitro study. European Cells and Materials 21 , pp. 508-522. |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2011. Tissue injury and repair : meniscus. Hutson, Mike and Speed, Cathy, eds. Sports Injuries, Oxford: Oxford, pp. 45-53. |
Thomas, Rhian Sara, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2011. Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis. Arthritis Research and Therapy 13 (6) , R203. 10.1186/ar3536 |
Wann, Angus K. T., Mistry, Jiten, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Michael-Titus, Adina T. and Knight, Martin M. 2010. Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin-1β-mediated cartilage degradation. Arthritis Research & Therapy 12 (6) , R207. 10.1186/ar3183 |
Li, S., Jia, X., Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2009. The effects of cyclic tensile strain on cytoskeleton in intervertebral disc cell: a preliminary study in vitro [Abstract]. International Journal of Experimental Pathology 90 (2) , A120. 10.1111/j.1365-2613.2008.00644.x |
Harrison, R. J., Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Wardale, R. J. and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2009. Involvement of the cytoskeleton in the regulation of articular chondrocyte phenotype in 3D-culture [Abstract]. International Journal of Experimental Pathology 90 (2) , A112-A113. 10.1111/j.1365-2613.2008.00644.x |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Hughes, N., Kozaci, L. D. and Sutton, C. 2009. Cartilage metabolism and cell based therapies for tissue regeneration [Conference Report]. International Journal of Experimental Pathology 90 (2) , A85-A93. 10.1111/j.1365-2613.2008.00644.x |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2009. The role of the cytoskeleton in articular chondrocyte metabolism [Abstract]. International Journal of Experimental Pathology 90 (1) , A45. 10.1111/j.1365-2613.2008.00612.x |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2009. Involvement of the cytoskeletal elements in articular cartilage homeostasis and pathology. International Journal of Experimental Pathology 90 (1) , pp. 1-15. 10.1111/j.1365-2613.2008.00625.x |
Harrison, R. J., Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Wardale, R. J. and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2009. Comparison of gene expression of human chondrocytes in monolayer and 3D-culture [Abstract]. International Journal of Experimental Pathology 90 (1) , A66. 10.1111/j.1365-2613.2008.00612.x |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2009. BSMB young investigator award abstract the role of the cytoskeleton in articular chondrocyte metabolism. International Journal of Experimental Pathology 90 (1) , A45-A45. 10.1111/j.1365-2613.2008.00612.x |
Davies, Lindsay Catrina ORCID: https://orcid.org/0000-0002-4876-6270, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2008. Chondroitin sulphate impedes the migration of a sub-population of articular cartilage chondrocytes. Osteoarthritis and Cartilage 16 (8) , pp. 855-864. 10.1016/j.joca.2007.12.005 |
Davies, L. C., Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254, Gilbert, Sophie Jane, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Duance, Victor ORCID: https://orcid.org/0000-0002-7555-2016 2008. The potential of IGF-1 and TGFβ1 for promoting “adult” articular cartilage repair: An in vitro study. Tissue Engineering Part A 14 (7) , pp. 1251-1261. 10.1089/ten.tea.2007.0211 |
Li, Siyuan, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2008. Zonal variations in cytoskeletal element organization, mRNA and protein expression in the intervertebral disc. Journal of Anatomy 213 (6) , pp. 725-732. 10.1111/j.1469-7580.2008.00998.x |
Bazou, Despina, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 and Terence Coakley, W. 2008. NCAM and PSA-NCAM dependent membrane spreading and F-actin reorganization in suspended adhering neural cells. Molecular Membrane Biology 25 (2) , pp. 102-114. 10.1080/09687680701618365 |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Li, S. and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2007. F-actin cytoskeletal organization in intervertebral disc health and disease. Biochemical Society Transactions 35 (4) , pp. 683-685. 10.1042/BST0350683 |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2007. Mechanical regulation of matrix metalloproteinases. Frontiers in Bioscience 12 (1) , pp. 507-527. 10.2741/2078 |
Campbell, J. J., Blain, Emma jane ORCID: https://orcid.org/0000-0001-8944-4254, Chowdhury, T. T. and Knight, M. M. 2007. Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes. Biochemical and Biophysical Research Communications 361 (2) , pp. 329-334. 10.1016/j.bbrc.2007.06.185 |
Davies, L., Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2006. Comparing the responsiveness of chondrocytes isolated from young and mature articular cartilage to IGF-1 and TGFβ1. European Cells and Materials 12 (Supp 1) , p. 54. |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2006. Maintenance of chondrocyte phenotype by the vimentin intermediate filaments [Abstract]. European Cells and Materials 12 (S. 1) , p. 53. |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Donaldson, E. and Cheung, F. 2005. British Society for Matrix Biology Spring 2005 meeting. University of Liverpool. Collagen-from genes to fibrils. International Journal of Experimental Pathology 86 (6) , A57-A94. 10.1111/j.0959-9673.2005.00454.x |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Gilbert, Sophie Jane and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2005. An intact cytoskeleton is essential to maintain articular cartilage chondrocyte metabolism. International Journal of Experimental Pathology 86 (3) , A10-A11. 10.1111/j.0959-9673.2005.00426.x |
Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Gilbert, Sophie Jane, Wardale, Robert John, Capper, S. J., Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2001. Up-regulation of matrix metalloproteinase expression and activation following cyclical compressive loading of articular cartilage in vitro. Archives of biochemistry and biophysics 396 (1) , pp. 49-55. 10.1006/abbi.2001.2575 |