Objective Assessment of progression in Huntington's Disease: a 3 year follow-up study

Reilmann, R., Kirsten, F., Quinn, Lori ORCID: https://orcid.org/0000-0002-2982-923X, Henningsen, H., Marder, K. and Gordon, A. M. 2001. Objective Assessment of progression in Huntington's Disease: a 3 year follow-up study. Neurology 57 (5) , pp. 920-924.

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Abstract

Objective measures to assess progression of Huntington’s disease (HD) are desirable. The authors have previously found that patients with HD with higher Unified Huntington’s Disease Rating Scale (UHDRS) motor scores exhibited higher variability of isometric grip forces while grasping an object. Therefore, the authors assessed grip force variability during this task in 10 HD patients with a 3-year follow-up. Grip force variability increased in all patients at the follow-up. Thus, grip force variability during grasping might be an objective and quantitative measure to assess motor deficits associated with the progression of HD.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Healthcare Sciences
Subjects:	R Medicine > RC Internal medicine
Publisher:	American Academy of Neurology
ISSN:	0028-3878
Last Modified:	19 Oct 2022 08:59
URI:	https://orca.cardiff.ac.uk/id/eprint/19675

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