Biological adhesive composition and method of promoting adhesion between tissue surfaces

Orthogene, Inc 1996. Biological adhesive composition and method of promoting adhesion between tissue surfaces. US patent 5,549,904. [Patent].

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Abstract

A formulated biological adhesive composition utilizes tissue transglutaminase in a pharmaceutically acceptable aqueous carrier. The tissue transglutaminase is used in an effective catalytic amount to promote adhesion between tissue surfaces upon treatment thereof by catalyzing the reaction between glutaminyl residues and amine donors of the tissue and/or the enzyme. The carrier contains a divalent metal ion such as calcium to promote said reaction.

Item Type:	Patent
Date Type:	Publication
Status:	Published
Schools:	Dentistry
Subjects:	R Medicine > R Medicine (General)
Last Modified:	19 Oct 2022 10:18
URI:	https://orca.cardiff.ac.uk/id/eprint/23911

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