First description of klebsiella pneumoniae clinical isolates carrying both qnrA and qnrB genes in Portugal

Ferreira, Sonia, Toleman, Mark Alexander Howard ORCID: https://orcid.org/0000-0002-9497-0512, Ramalheira, Elmano, Da Silva, Gabriela J., Walsh, Timothy Rutland ORCID: https://orcid.org/0000-0003-4315-4096 and Mendo, Sónia 2010. First description of klebsiella pneumoniae clinical isolates carrying both qnrA and qnrB genes in Portugal. International Journal of Antimicrobial Agents 35 (6) , pp. 584-586. 10.1016/j.ijantimicag.2010.01.019

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Abstract

In the present study, 21 multidrug-resistant Klebsiella pneumoniae isolates were recovered from patients hospitalised in the Intensive Care Unit of Hospital Infante D. Pedro in Aveiro, Portugal. Fifteen isolates carried qnr genes. Four strains harboured the quinolone resistance genes qnrA and qnrB, both located on a large plasmid in two strains (KP4 and KP10) and on different plasmids in two strains (KP5 and KP6). These findings indicate an extremely high prevalence of qnr genes associated with various mobile elements such as ISCR1 and class 1 integrons.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine Systems Immunity Research Institute (SIURI)
Subjects:	Q Science > QH Natural history > QH426 Genetics R Medicine > R Medicine (General)
Uncontrolled Keywords:	qnr genes, quinolone resistance, klebsiella pneumoniae
Publisher:	Elsevier
ISSN:	0924-8579
Last Modified:	19 Oct 2022 10:42
URI:	https://orca.cardiff.ac.uk/id/eprint/25288

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