Stereoselective synthesis of 3,4-disubstituted tetrahydrofurans and 2,3,4-trisubstituted tetrahydrofurans using an intramolecular allylation strategy employing allylsilanes

Jervis, Peter J., Kariuki, Benson ORCID: https://orcid.org/0000-0002-8658-3897 and Cox, Liam R. 2008. Stereoselective synthesis of 3,4-disubstituted tetrahydrofurans and 2,3,4-trisubstituted tetrahydrofurans using an intramolecular allylation strategy employing allylsilanes. Tetrahedron Letters 49 (16) , pp. 2514-2518. 10.1016/j.tetlet.2008.02.088

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Abstract

A Bronsted acid-mediated intramolecular allylation involving an allylsilane and an aldehyde has been used as the key step in a stereoselective synthesis of 3,4-disubstituted tetrahydrofurans and 2,3,4-trisubstituted tetrahydrofurans.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Chemistry
Subjects:	Q Science > QD Chemistry
Publisher:	Pergamon-Elsevier Science
ISSN:	0040-4039
Last Modified:	19 Oct 2022 10:44
URI:	https://orca.cardiff.ac.uk/id/eprint/25354

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