| Van Hecke, Wim, Sijbers, Jan, D'Agostino, Emiliano, Maes, Frederik, De Backer, Steve, Vandervliet, Evert, Parizel, Paul M. and Leemans, Alexander 2008. On the construction of an inter-subject diffusion tensor magnetic resonance atlas of the healthy human brain. NeuroImage 43 (1) , pp. 69-80. 10.1016/j.neuroimage.2008.07.006 |
Abstract
Voxel based morphometry (VBM) has been increasingly applied to detect diffusion tensor (DT) image abnormalities in patients for different pathologies. An important requisite for a robust VBM analysis is the availability of a high-dimensional non-rigid coregistration technique that is able to align both the spatial and the orientational DT information. Consequently, there is a need for an inter-subject DTI atlas as a group specific reference frame that also contains this orientational DT information. In this work, a population based DTI atlas has been developed that incorporates such orientational DT information with high accuracy and precision. The proposed methodology for constructing such an atlas is compared with a subject based DTI atlas, in which a single subject is selected as the reference image. Our results demonstrate that the population based atlas framework is more accurate with respect to the underlying diffusion information.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Cardiff University Brain Research Imaging Centre (CUBRIC) Psychology |
| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Uncontrolled Keywords: | Diffusion tensor imaging; Non-rigid coregistration; Inter-subject group atlas; Diffusion tensor tractography |
| Publisher: | Elsevier |
| ISSN: | 1053-8119 |
| Last Modified: | 12 Jun 2019 02:28 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/26668 |
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