Molecular analysis of the sequences surrounding blaOXA-45 reveals acquisition of this gene by pseudomonas aeruginosa via a novel ISCR element, ISCR5

Li, H., Walsh, Timothy Rutland ORCID: https://orcid.org/0000-0003-4315-4096 and Toleman, Mark Alexander Howard ORCID: https://orcid.org/0000-0002-9497-0512 2008. Molecular analysis of the sequences surrounding blaOXA-45 reveals acquisition of this gene by pseudomonas aeruginosa via a novel ISCR element, ISCR5. Antimicrobial Agents and Chemotherapy 53 (3) , pp. 1248-1251. 10.1128/AAC.00480-08

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Abstract

The blaOXA-45 gene of Pseudomonas aeruginosa 07-406 is driven by a promoter found within a truncated ISPme1 insertion sequence. The gene is located between nonidentical repeats of a new ISCR element, ISCR5, which is likely responsible for its acquisition. Sequence analysis indicates that ISCR5 is a chimera of ISCR3 and ISCR16.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine Research Institutes & Centres > Systems Immunity Research Institute (SIURI)
Subjects:	Q Science > QH Natural history > QH426 Genetics Q Science > QR Microbiology
Additional Information:	Pdf uploaded in accordance with publisher's policy at http://www.sherpa.ac.uk/romeo/issn/0066-4804/ (accessed 24/02/2014)
Publisher:	American Society for Microbiology
ISSN:	0066-4804
Date of First Compliant Deposit:	30 March 2016
Last Modified:	08 May 2023 09:37
URI:	https://orca.cardiff.ac.uk/id/eprint/27253

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