Modelling the response of whispering-gallery-mode optical resonators for biosensing applications

Langbein, Wolfgang Werner ORCID: https://orcid.org/0000-0001-9786-1023, Chantada, Laura, Nikolaev, Nikolay Irmanov, Ivanov, Alexei and Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314 2009. Modelling the response of whispering-gallery-mode optical resonators for biosensing applications. Presented at: Nanoscale imaging, sensing, and actuation for biomedical applications 6, San Jose, CA, USA, 27-28 January 2009. Published in: Cartwright, A. N. and Nicolau, D. V. eds. Proceedings of the Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VI conference, San Jose, USA, 27 January 2009. Proceedings of SPIE (7188) Bellingham, WA: SPIE, 71880G. 10.1117/12.808790

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Abstract

We present a theoretical analysis of the response of whispering gallery modes for biosensing applications, studied numerically in microcylinders and semi-analytically in microspheres. The effect of single and multiple particles is calculated, simulating biological analytes of different sizes and polarizabilities attached to the microresonator surface. Besides whispering-gallery-mode frequency shifts, we find that also broadenings and splittings (from lifted rotational symmetry) appear due to particles attachment and/or the vicinity to a planar coupler. For a single analyte, both particle size and refractive index can be determined from the broadening and shift, opening the perspective to a new biosensing modality.

Item Type:	Conference or Workshop Item (Paper)
Date Type:	Publication
Status:	Published
Schools:	Physics and Astronomy Biosciences
Subjects:	Q Science > QC Physics Q Science > QH Natural history > QH301 Biology
Uncontrolled Keywords:	Biosensing ; Microresonators ; Modeling ; Optical resonators ; Particles ; Polarizability ; Refractive index
Publisher:	SPIE
ISBN:	9780819474346
Last Modified:	06 Oct 2024 15:05
URI:	https://orca.cardiff.ac.uk/id/eprint/27363

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