A novel method for the genome-wide high resolution analysis of DNA damage

Teng, Yumin, Bennett, Mark Richard, Evans, Katie Ellen, Zhuang Jackson, Huayun, Higgs, Andy, Reed, Simon Huw ORCID: https://orcid.org/0000-0002-4711-0560 and Waters, Raymond 2011. A novel method for the genome-wide high resolution analysis of DNA damage. Nucleic Acids Research 39 (2) , e10. 10.1093/nar/gkq1036

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Abstract

DNA damage occurs via endogenous and exogenous genotoxic agents and compromises a genome’s integrity. Knowing where damage occurs within a genome is crucial to understanding the repair mechanisms which protect this integrity. This paper describes a new development based on microarray technology which uses ultraviolet light induced DNA damage as a paradigm to determine the position and frequency of DNA damage and its subsequent repair throughout the entire yeast genome.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine
Subjects:	Q Science > QH Natural history > QH426 Genetics R Medicine > R Medicine (General)
Publisher:	Oxford University Press
ISSN:	0305-1048
Last Modified:	06 Jun 2024 17:50
URI:	https://orca.cardiff.ac.uk/id/eprint/27752

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